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Note 4 - Fair Value Measurements (Tables)
6 Months Ended
Jun. 30, 2018
Notes Tables  
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
         
Fair Value Measurements at Reporting Date Using
 
   
 
 
 
 
Quoted Prices in
   
Significant
   
 
 
 
   
 
 
 
 
Active Markets
   
Other
   
Significant
 
   
Balance at
   
for Identical
   
Observable
   
Unobservable
 
   
June 30
,
   
Assets
   
Inputs
   
Inputs
 
   
201
8
   
(Level 1)
   
(Level 2)
   
(Level 3)
 
Money market funds
  $
237,705
    $
237,705
    $
    $
 
U.S. treasury bills
   
39,771
     
39,771
     
     
 
U.S. corporate debt securities
   
19,153
     
     
19,153
     
 
U.S. commercial paper
   
59,788
     
     
59,788
     
 
Foreign commercial paper
   
63,304
     
     
63,304
     
 
Total
  $
419,721
    $
277,476
    $
142,245
    $
 
         
Fair Value Measurements at Reporting Date Using
 
   
 
 
 
 
Quoted Prices in
   
Significant
   
 
 
 
   
 
 
 
 
Active Markets
   
Other
   
Significant
 
   
Balance at
   
for Identical
   
Observable
   
Unobservable
 
   
December
31,
   
Assets
   
Inputs
   
Inputs
 
   
201
7
   
(Level 1)
   
(Level 2)
   
(Level 3)
 
Money market funds
  $
91,386
    $
91,386
    $
    $
 
U.S. corporate debt securities
   
17,520
     
     
17,520
     
 
U.S. commercial paper
   
39,863
     
     
39,863
     
 
Foreign commercial paper
   
19,854
     
     
19,854
     
 
Total
  $
168,623
    $
91,386
    $
77,237
    $