    <SEC-DOCUMENT>0001193125-18-140991-index.html : 20180430
    <SEC-HEADER>0001193125-18-140991.hdr.sgml : 20180430
    <ACCEPTANCE-DATETIME>20180430083655
    ACCESSION NUMBER:		0001193125-18-140991
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		3
    FILED AS OF DATE:		20180430
    DATE AS OF CHANGE:		20180430
    EFFECTIVENESS DATE:		20180430

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
    		CENTRAL INDEX KEY:			0000818033
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				942875566
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33221
    		FILM NUMBER:		18786831

    	BUSINESS ADDRESS:
    		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		6503662626

    	MAIL ADDRESS:
    		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
    		DATE OF NAME CHANGE:	20010511

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
    		DATE OF NAME CHANGE:	19920703
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>d554102ddefa14a.htm
    <DESCRIPTION>DEFA14A
    <TEXT>
    Document 1 - file: d554102ddefa14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g554102img01.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g554102img01.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g554102img02.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g554102img02.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>