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Note 4 - Balance Sheet Details (Details Textual) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Jan. 01, 2018
Other-than-temporary Impairment Loss, Debt Securities, Available-for-sale, Total $ 0 $ 0    
Inventory, Net, Total 39,032 10,108   $ 9,910
Depreciation, Total 1,500 1,500 $ 1,100  
Construction in Progress, Gross 10,300 2,000    
SUSTOL [Member]        
Inventory, Net, Total 6,700 7,100    
CINVANTI [Member]        
Inventory, Net, Total $ 32,300 $ 3,000