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Note 3 - Accounting Policies - Percentage of Net Product Sales and Accounts Receivable Balance (Details) - Customer Concentration Risk [Member]	3 Months Ended
	Mar. 31, 2019
Revenue Benchmark [Member]
Concentration risk percentage	97.70%
Revenue Benchmark [Member] | Largest Customer [Member]
Concentration risk percentage	40.70%
Revenue Benchmark [Member] | Second Largest Customer [Member]
Concentration risk percentage	36.60%
Revenue Benchmark [Member] | Third Largest Customer [Member]
Concentration risk percentage	20.40%
Accounts Receivable [Member]
Concentration risk percentage	99.00%
Accounts Receivable [Member] | Largest Customer [Member]
Concentration risk percentage	42.30%
Accounts Receivable [Member] | Second Largest Customer [Member]
Concentration risk percentage	39.20%
Accounts Receivable [Member] | Third Largest Customer [Member]
Concentration risk percentage	17.50%

X

- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 275
-SubTopic 10
-Section 50
-Paragraph 18
-URI http://asc.fasb.org/extlink&oid=99393423&loc=d3e6351-108592

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 825
-SubTopic 10
-Section 50
-Paragraph 20
-URI http://asc.fasb.org/extlink&oid=118260190&loc=d3e13531-108611

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 825
-SubTopic 10
-Section 50
-Paragraph 21
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=118260190&loc=d3e13537-108611

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 275
-SubTopic 10
-Section 50
-Paragraph 20
-URI http://asc.fasb.org/extlink&oid=99393423&loc=d3e6404-108592

+ Details

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- Details

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- Details

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