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Inventory - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Inventory [Line Items]          
Total inventory $ 24,172   $ 24,172   $ 39,032
Cost of product sales 17,195 $ 7,576 45,745 $ 15,940  
SUSTOL          
Inventory [Line Items]          
Total inventory 1,200   1,200   6,700
Cost of product sales 1,700   3,300    
CINVANTI          
Inventory [Line Items]          
Total inventory $ 23,000   $ 23,000   $ 32,300