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Stockholders' Equity - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended		3 Months Ended						9 Months Ended
	Jun. 30, 2018	Apr. 30, 2018	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Sep. 30, 2019	Sep. 30, 2018
Class Of Stock [Line Items]
Payments of stock issuance costs									$ 110
Proceeds from issuance of common stock	$ 194,400	$ 168,700								$ 363,128
Shares of common stock issued pursuant to exercise of stock options									1,793,000
Proceeds from stock option exercises									$ 20,239	$ 15,771
Total unrecognized compensation cost related to non-vested, stock-based payment awards			$ 80,200						$ 80,200
Total unrecognized compensation cost, expect to recognize over weighted average period									2 years 7 months 6 days
Common Stock
Class Of Stock [Line Items]
Number of shares issued	5,100,000	6,900,000					11,963,000
Share price	$ 39.50	$ 26.00					$ 39.50
Payments of stock issuance costs	$ 5,600	$ 10,700
Shares of common stock issued pursuant to exercise of stock options			251,000	810,000	732,000	393,000	504,000	435,000

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