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Stockholders' Equity - Summary of Stock-Based Compensation Expense related to Stock-Based Payment Awards Granted (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense $ 9,704 $ 8,050 $ 40,312 $ 23,572
Research and Development Expense        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense 4,365 3,212 14,123 9,363
General and Administrative Expense        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense 2,939 2,366 10,333 6,950
Selling and Marketing Expense        
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]        
Stock-based compensation expense $ 2,400 $ 2,472 $ 15,856 $ 7,259