<SEC-DOCUMENT>0001209191-19-010097.txt : 20190214
<SEC-HEADER>0001209191-19-010097.hdr.sgml : 20190214
<ACCEPTANCE-DATETIME>20190214160214
ACCESSION NUMBER:		0001209191-19-010097
CONFORMED SUBMISSION TYPE:	5
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20181231
FILED AS OF DATE:		20190214
DATE AS OF CHANGE:		20190214

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			TANG KEVIN C
		CENTRAL INDEX KEY:			0001178579

	FILING VALUES:
		FORM TYPE:		5
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		19605905

	MAIL ADDRESS:	
		STREET 1:		4747 EXECUTIVE DRIVE
		STREET 2:		SUITE 510
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
		CENTRAL INDEX KEY:			0000818033
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				942875566
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		8582514400

	MAIL ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
		DATE OF NAME CHANGE:	20010511

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
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<DESCRIPTION>FORM 5 SUBMISSION
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    <footnotes>
        <footnote id="F1">The gifted securities were held by Tang Capital Partners, LP and were donated to a charitable organization.</footnote>
        <footnote id="F2">The securities are held by Tang Capital Partners, LP (&quot;TCP&quot;). Kevin Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of TCP. Mr. Tang has a pecuniary interest in a portion of the shares beneficially held by TCP.</footnote>
        <footnote id="F3">The securities are held by Kevin Tang as custodian for his minor children, as Trustee of the KCT Family Trust, and as Trustee of the
Tang Advisors, LLC Profit Sharing Plan.</footnote>
        <footnote id="F4">2,147 of these securities are held by Kevin Tang's IRA.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Kevin Tang</signatureName>
        <signatureDate>2019-02-14</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</SEC-DOCUMENT>
