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Stockholders' Equity (Tables)

6 Months Ended

Jun. 30, 2020

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of Stock Option Activity

The following table summarizes the stock option activity for the six months ended June 30, 2020:

		Shares (in thousands)				Weighted- average Exercise Price				Weighted- average Remaining Contractual Term (Years)
Balance at December 31, 2019			16,665			$	20.47				7.87
Granted			249			$	19.24
Exercised			(124	)		$	10.57
Expired and forfeited			(484	)		$	22.57
Balance at June 30, 2020			16,306			$	20.46				7.31

Summary of Stock-Based Compensation Expense related to Stock-Based Payment Awards Granted

The following table summarizes stock-based compensation expense related to stock-based payment awards granted pursuant to all of our equity compensation arrangements (in thousands):

		Three Months Ended June 30,								Six Months Ended June 30,
		2020				2019				2020				2019
Research and development		$	4,681			$	4,434			$	9,968			$	9,758
General and administrative			3,304				3,714				6,735				7,394
Sales and marketing			3,129				4,558				6,385				13,456
Total stock-based compensation expense		$	11,114			$	12,706			$	23,088			$	30,608

Summary of Fair Value of Option Grant on Grant Date Using Black-Scholes Option Pricing Model

We estimated the fair value of each option grant on the grant date using the Black-Scholes option pricing model with the following weighted-average assumptions:

		June 30,
		2020				2019
Risk-free interest rate			1.1	%			2.4	%
Dividend yield			0.0	%			0.0	%
Volatility			66.7	%			68.0	%
Expected life (years)			6				6

1997 Employee Stock Purchase Plan

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of Fair Value of Option Grant on Grant Date Using Black-Scholes Option Pricing Model

We estimated the fair value of each purchase right granted under our 1997 Employee Stock Purchase Plan, as amended, at the beginning of each new offering period using the Black-Scholes option pricing model with the following weighted-average assumptions:

		June 30,
		2020				2019
Risk-free interest rate			0.1	%			2.4	%
Dividend yield			0.0	%			0.0	%
Volatility			63.3	%			58.4	%
Expected life (months)			6				6

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