<SEC-DOCUMENT>0001214659-20-009760.txt : 20201119
<SEC-HEADER>0001214659-20-009760.hdr.sgml : 20201119
<ACCEPTANCE-DATETIME>20201119160009
ACCESSION NUMBER:		0001214659-20-009760
CONFORMED SUBMISSION TYPE:	SC 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20201119
DATE AS OF CHANGE:		20201119
GROUP MEMBERS:		KEVIN TANG
GROUP MEMBERS:		TANG CAPITAL MANAGEMENT, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
		CENTRAL INDEX KEY:			0000818033
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				942875566
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-39444
		FILM NUMBER:		201328796

	BUSINESS ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		8582514400

	MAIL ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
		DATE OF NAME CHANGE:	20010511

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TANG CAPITAL PARTNERS LP
		CENTRAL INDEX KEY:			0001191935
		IRS NUMBER:				680517277
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G

	BUSINESS ADDRESS:	
		STREET 1:		4747 EXECUTIVE DRIVE
		STREET 2:		SUITE 210
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		858-200-3830

	MAIL ADDRESS:	
		STREET 1:		4747 EXECUTIVE DRIVE
		STREET 2:		SUITE 210
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G
<SEQUENCE>1
<FILENAME>g86201sc13g.htm
<TEXT>
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<P STYLE="margin: 0">&nbsp;</P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0"></P>


<P STYLE="font: 14pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Securities
and Exchange Commission</B></FONT></P>

<P STYLE="font: 12pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="font-variant: small-caps"><B>Washington,
DC 20549</B></FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman; margin: 0pt 0; text-align: center"><B>SCHEDULE 13G</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="font-variant: small-caps"><B>Under the Securities
Exchange Act of 1934</B></FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="font-variant: small-caps"><B>Schedule 13G
to amend the Schedule 13D filed by Tang Capital Partners, LP and related parties on October 14, 2008</B></FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 24pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B><U>Heron Therapeutics, Inc.</U></B></P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Name of Issuer)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><B><U>Common Stock, par value $0.01 per share</U></B></P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Title of Class of Securities)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B><U>427746102</U></B></P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(CUSIP Number)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><B><U>August 4, 2020</U></B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center">(Date of Event Which Requires Filing of This Statement)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: justify">Check the appropriate box to designate the rule pursuant
to which this Schedule is filed:</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><tr style="vertical-align: top">
<td style="width: 36pt"></td><td style="width: 36pt; text-align: left"><font style="font-family: Times New Roman, Times, Serif">&#9744;</font></td><td>Rule 13d-1(b)</td>
</tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><tr style="vertical-align: top">
<td style="width: 36pt"></td><td style="width: 36pt; text-align: left"><font style="font-family: Wingdings">&yacute;</font></td><td>Rule 13d-1(c)</td>
</tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><tr style="vertical-align: top">
<td style="width: 36pt"></td><td style="width: 36pt; text-align: left"><font style="font-family: Times New Roman, Times, Serif">&#9744;</font></td><td>Rule 13d-1(d)</td>
</tr></table>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: justify">*The remainder of this cover page shall be filled out
for a reporting person&rsquo;s initial filing on this form with respect to the subject class of securities, and for any subsequent
amendment containing information which would alter the disclosures provided in a prior cover page.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: justify">The information required in the remainder of this cover
page shall not be deemed to be &ldquo;filed&rdquo; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&ldquo;Act&rdquo;)
or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,
see the Notes).</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 12pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; border-bottom: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0"></P>

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    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->1<!-- Field: /Sequence --> of 10 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 39%">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><B>CUSIP No. 427746102</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P></TD>
    <TD STYLE="width: 30%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt"><B>13G</B></FONT></TD>
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 31%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>Page 2 of 10 Pages</B></FONT></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>1</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">NameS of Reporting
        Persons<BR>
        I.R.S. Identification NOS. of Above Persons (ENTITIES ONLY)</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">TANG CAPITAL PARTNERS,
        LP</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt; width: 6%"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>2</B></FONT></TD>
    <TD STYLE="text-align: left; font-size: 12pt; width: 84%"><FONT STYLE="font-size: 10pt; text-transform: uppercase">Check
the Appropriate Box if a Member of a Group*</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: left; font-size: 12pt; width: 10%">        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;<font style="font-family: Wingdings">&uml;</font></p>
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;<font style="font-family: Wingdings">&yacute;</font></p></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>3</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; background-color: #CCCCCC">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">SEC Use Only</FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>4</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Citizenship or Place
        of Organization</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">DELAWARE</FONT></P>

</TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="vertical-align: bottom; width: 24%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Number of</FONT></TD>
    <TD STYLE="vertical-align: top; width: 7%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>5</B></FONT></TD>
    <TD STYLE="vertical-align: top; width: 69%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">Shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">BENEFICIALLY<BR>
        Owned by</FONT></P></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>6</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Each Reporting <BR>
Person with</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>7</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt">&nbsp;</TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>8</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 7%; border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>9</B></FONT></TD>
    <TD STYLE="width: 93%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Aggregate Amount
        Beneficially Owned by each Reporting Person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>10</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Check Box if the
        Aggregate Amount in Row (9) excludes certain shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Wingdings; margin: 0pt 34.7pt 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&uml;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>11</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Percent of Class
        represented by amount in row 9</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">9.86%</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>12</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">type of reporting
        person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">pN</FONT></P>

</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>


<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 39%">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><B>CUSIP No. 427746102</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P></TD>
    <TD STYLE="width: 30%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt"><B>13G</B></FONT></TD>
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 31%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>Page 3 of 10 Pages</B></FONT></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>1</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">NameS of Reporting
        Persons<BR>
        I.R.S. Identification NOS. of Above Persons (ENTITIES ONLY)</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Tang Capital Management,
        LLC</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt; width: 6%"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>2</B></FONT></TD>
    <TD STYLE="text-align: left; font-size: 12pt; width: 84%"><FONT STYLE="font-size: 10pt; text-transform: uppercase">Check
the Appropriate Box if a Member of a Group*</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: left; font-size: 12pt; width: 10%">        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;<font style="font-family: Wingdings">&uml;</font></p>
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;<font style="font-family: Wingdings">&yacute;</font></p></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>3</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; background-color: #CCCCCC">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">SEC Use Only</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>4</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Citizenship or Place
        of Organization</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">DELAWARE</FONT></P>

</TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="vertical-align: bottom; width: 24%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Number of</FONT></TD>
    <TD STYLE="vertical-align: top; width: 7%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>5</B></FONT></TD>
    <TD STYLE="vertical-align: top; width: 69%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">Shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">BENEFICIALLY<BR>
        Owned by</FONT></P></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>6</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Each Reporting <BR>
Person with</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>7</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt">&nbsp;</TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>8</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 7%; border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>9</B></FONT></TD>
    <TD STYLE="width: 93%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Aggregate Amount
        Beneficially Owned by each Reporting Person </FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>10</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Check Box if the
        Aggregate Amount in Row (9) excludes certain shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Wingdings; margin: 0pt 34.7pt 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&uml;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>11</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Percent of Class
        represented by amount in row 9</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">9.86%</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>12</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">type of reporting
        person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">OO</FONT></P>

</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 3 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->3<!-- Field: /Sequence --> of 10 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 39%">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><B>CUSIP No. 427746102</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P></TD>
    <TD STYLE="width: 30%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt"><B>13G</B></FONT></TD>
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 31%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>Page
    4 of 10 Pages</B></FONT></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>1</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">NameS of Reporting
        Persons<BR>
        I.R.S. Identification NOS. of Above Persons (ENTITIES ONLY)</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Kevin Tang</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt; width: 6%"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>2</B></FONT></TD>
    <TD STYLE="text-align: left; font-size: 12pt; width: 84%"><FONT STYLE="font-size: 10pt; text-transform: uppercase">Check
the Appropriate Box if a Member of a Group*</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: left; font-size: 12pt; width: 10%">        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;<font style="font-family: Wingdings">&uml;</font></p>
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;<font style="font-family: Wingdings">&yacute;</font></p></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>3</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; background-color: #CCCCCC">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">SEC Use Only</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>4</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Citizenship or Place
        of Organization</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">united states</FONT></P>

</TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="vertical-align: bottom; width: 24%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Number of</FONT></TD>
    <TD STYLE="vertical-align: top; width: 7%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>5</B></FONT></TD>
    <TD STYLE="vertical-align: top; width: 69%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">126,658</FONT></FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">Shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">BENEFICIALLY<BR>
        Owned by</FONT></P></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>6</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Each Reporting <BR>
Person with</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>7</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">126,658</FONT></FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt">&nbsp;</TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>8</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,622,686</FONT></FONT></P></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 7%; border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>9</B></FONT></TD>
    <TD STYLE="width: 93%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Aggregate Amount
        Beneficially Owned by each Reporting Person </FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase"><FONT STYLE="text-transform: uppercase">9,749,344</FONT></FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>10</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Check Box if the
        Aggregate Amount in Row (9) excludes certain shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Wingdings; margin: 0pt 34.7pt 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&uml;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>11</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Percent of Class
        represented by amount in row 9</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">9.99%</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>12</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">type of reporting
        person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">IN</FONT></P>

</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

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    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0"><B>Explanatory Note:</B> This Schedule 13G is being filed in accordance with
Rule 13d-1(h) to reflect that (i) Tang Capital Partners, LP, (ii) Tang Capital Management, LLC and (iii) Kevin Tang (the &ldquo;Reporting
Persons&rdquo;) no longer hold the securities with a purpose or effect of changing or influencing control of the Issuer due to
Kevin Tang&rsquo;s resignation from the Company&rsquo;s Board of Directors effective as of August 4, 2020. This Schedule 13G is
being filed as Amendment No. 20 to the Schedule 13D originally filed on Schedule 13G with the Securities and Exchange Commission
(the &ldquo;SEC&rdquo;) on October 14, 2008, as amended on November 10, 2008, November 24, 2008, December 29, 2008, February 18,
2009, October 26, 2009, June 3, 2010, May 3, 2011, July 7, 2011, May 11, 2012, July 30, 2012, May 9, 2013, November 22, 2013,
June 27, 2014, June 12, 2015, April 14, 2016, August 10, 2016, January 24, 2017, September 13, 2018 and January 7, 2020 (as amended,
the &ldquo;Statement&rdquo;), with respect to the Common Stock, $0.01 par value (the &ldquo;Common Stock&rdquo;), of Heron Therapeutics,
Inc., a Delaware corporation (the &ldquo;Issuer&rdquo; or &ldquo;Company&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 1(a).</B></TD><TD STYLE="text-align: left">Name of Issuer:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left; text-indent: 1in">Heron Therapeutics, Inc., a Delaware corporation
(the &ldquo;Issuer&rdquo;)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 1(b).</B></TD><TD STYLE="text-align: left">Address of Issuer&rsquo;s Principal Executive Offices:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left; text-indent: 1in">4242 Campus Point Court, Suite 200, San
Diego, CA 92121</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(a).</B></TD><TD STYLE="text-align: left">Name of Person Filing:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">This Statement on Schedule 13G (this &ldquo;Statement&rdquo;)
is filed by Tang Capital Partners, LP (&ldquo;Tang Capital Partners&rdquo;); Tang Capital Management, LLC, the general partner
of Tang Capital Partners (&ldquo;Tang Capital Management&rdquo;); and Kevin Tang, the manager of Tang Capital Management.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(b).</B></TD><TD STYLE="text-align: left"><B>A</B>ddress of Principal Business Office or, if none, Residence:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">4747 Executive Drive, Suite 210, San Diego, CA 92121</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(c).</B></TD><TD STYLE="text-align: left">Citizenship:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Tang Capital Partners is a Delaware limited partnership.
Tang Capital Management is a Delaware limited liability company. Mr. Tang is a United States citizen.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(d).</B></TD><TD STYLE="text-align: left">Title of Class of Securities:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Common Stock, par value $0.01 per share (the &ldquo;Common
Stock&rdquo;)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(e).</B></TD><TD STYLE="text-align: left">CUSIP Number: 427746102</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 3.</B></TD><TD STYLE="text-align: left"><B>Not applicable.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 4.</B></TD><TD STYLE="text-align: left"><B>Ownership.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 45pt"></TD><TD STYLE="width: 27pt">(a)</TD><TD STYLE="text-align: left">Amount Beneficially Owned:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"><B>Tang Capital Partners.</B> Tang Capital Partners
is the beneficial owner of <FONT STYLE="text-transform: uppercase">9,622,686 </FONT>shares of the Issuer&rsquo;s Common Stock,
including 937,500 shares of Common Stock held by Tang (APPA) Holdings, LLC (&ldquo;Tang Holdings&rdquo;), comprising: (i) the
2,886,904 shares beneficially owned by Tang Capital Partners, LP; and (ii) 6,735,782 shares currently issuable upon conversion
of the Notes (defined below).</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Tang Capital Partners shares voting and dispositive
power over such shares with Tang Capital Management and Kevin Tang.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Tang Capital Partners, LP is the record owner of $6,108,524
principal amount of Senior Secured Convertible Notes due 2021 (the &ldquo;Notes&rdquo;), which may be converted into Common Stock
at a conversion rate of 1,250 shares per $1,000 principal amount of Notes, subject to certain limitations discussed below. Tang
Capital Partners, LP has no right to convert the Notes to the extent that after giving effect to such conversion Tang Capital Partners,
LP (together with its affiliates) would beneficially own in excess of the Maximum Percentage, which is currently set at 9.99%,
of the number of shares of Common Stock of the Company outstanding immediately after giving effect to such conversion. Tang Capital
Partners, LP can increase or decrease the Maximum Percentage for its Notes by written notice to the Company, provided that such
increase or decrease will not be effective until 61 days after delivery of the notice. The foregoing limitations remain in effect
with respect to such Notes, and, accordingly, only 6,735,782 shares are currently issuable upon conversion of such Notes.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Tang Capital Partners serves as the Manager of Tang
Holdings and, as such, exercises voting and dispositive control over the shares held by Tang Holdings.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"><B>Tang Capital Management.</B> Tang Capital Management,
as the general partner of Tang Capital Partners, may be deemed to beneficially own the shares of the Issuer&rsquo;s Common Stock
beneficially owned by Tang Capital Partners. Tang Capital Management shares voting and dispositive power over such shares with
Tang Capital Partners, LP and Kevin Tang.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"><B>Kevin Tang.</B> Kevin Tang is the beneficial owner of 9,749,344 shares of Common
Stock, comprising: (i) the <FONT STYLE="text-transform: uppercase">9,622,686 </FONT>shares beneficially owned by Tang Capital Partners,
LP; (ii) 114,232 shares held by the Kevin C. Tang Family Trust, for which Kevin Tang serves as trustee; (iii) 4,794 shares owned
directly by Kevin Tang; (iv) 3,445 shares owned by Kevin Tang&rsquo;s minor children under the Uniform Transfers to Minors Act,
for which Kevin Tang serves as trustee; (v) 2,147 shares held by Kevin Tang&rsquo;s Individual Retirement Account; and (vi) 2,040
shares owned by the Tang Advisors, LLC Profit Sharing Plan, for which Kevin Tang serves as trustee and is a participant.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Tang Capital Management, LLC, as the general partner
of Tang Capital Partners, LP, and Kevin Tang, as the manager of Tang Capital Management, LLC, may also be deemed to beneficially
own the shares beneficially owned by Tang Capital Partners, LP. Kevin Tang is a beneficiary and the sole trustee of the Kevin C.
Tang Family Trust and has voting and dispositive power over the shares held by the Kevin C. Tang Family Trust. The mailing address
of all of the foregoing persons and entities is c/o Tang Capital Management, LLC, 4747 Executive Drive, Suite 210, San Diego, CA
92121.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">The percentages used herein are based on 97,591,036 shares of
Common Stock outstanding (90,855,254 reported to be issued and outstanding in the Company&rsquo;s Quarterly Report on Form 10-Q
that was filed with the SEC on November 5, 2020, plus an additional 6,735,782 shares of Common Stock currently issuable upon conversion
of the Notes).</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

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    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 45pt"></TD><TD STYLE="width: 27pt">(b)</TD><TD STYLE="text-align: left">Percent of Class:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 80%; border-collapse: collapse; margin-left: 1in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">9.86%</FONT></TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">9.86%</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">9.99%</FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 45pt"></TD><TD STYLE="width: 27pt">(c)</TD><TD STYLE="text-align: left">Number of shares as to which such person has:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(i)</TD><TD STYLE="text-align: left">sole power to vote or to direct the vote:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">126,658</FONT> shares</FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(ii)</TD><TD STYLE="text-align: left">shared power to vote or to direct the vote:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">9,622,686</FONT> shares</FONT></TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">9,622,686</FONT> shares</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">9,622,686</FONT> shares</FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(iii)</TD><TD STYLE="text-align: left">sole power to dispose or to direct the disposition of:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">126,658</FONT> shares</FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(iv)</TD><TD STYLE="text-align: left">shared power to dispose or to direct the disposition of:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">9,622,686</FONT> shares</FONT></TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">9,622,686</FONT> shares</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><FONT STYLE="text-transform: uppercase">9,622,686</FONT> shares</FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 5.</B></TD><TD STYLE="text-align: left"><B>Ownership of Five Percent or Less of a Class.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 45.35pt; text-align: left"><FONT STYLE="font-family: Times New Roman">If this
statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner
of more than five percent of the class of securities, check the following: </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">o</FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 6.</B></TD><TD STYLE="text-align: left"><B>Ownership of More than Five Percent on Behalf of Another Person.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 7.</B></TD><TD STYLE="text-align: left"><B>Identification and Classification of the Subsidiary Which Acquired the Security Being Reported
on by the Parent Holding Company.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 8.</B></TD><TD STYLE="text-align: left"><B>Identification and Classification of Members of the Group.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 9.</B></TD><TD STYLE="text-align: left"><B>Notice of Dissolution of Group.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

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    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 10.</B></TD><TD STYLE="text-align: left"><B>Certification.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">By signing below I certify that, to the best of
my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect
of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with
or as a participant in any transaction having that purpose or effect.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

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    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Signature</B></FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">After reasonable inquiry and to the best of my knowledge
and belief, I certify that the information set forth in this statement is true, complete and correct.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 1pt; width: 3%; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Date:</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; padding-left: 9pt; text-align: justify; width: 25%"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">November
    19, 2020</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; width: 20%; text-align: left;">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; width: 52%; text-align: left;"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">&nbsp;</FONT></TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">TANG CAPITAL PARTNERS, LP</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">By: Tang Capital Management, LLC, its General Partner</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 1pt; width: 3%; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">By:</FONT></TD>
    <TD STYLE="padding-left: 9pt; border-bottom: Black 1pt solid; width: 25%; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">/s/
    Kevin Tang</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; width: 20%">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; width: 52%; text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="padding-left: 9pt; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang, Manager</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">TANG CAPITAL MANAGEMENT, LLC</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="padding-bottom: 1pt; width: 3%; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">By:</FONT></TD>
    <TD STYLE="padding-left: 9pt; border-bottom: Black 1pt solid; width: 25%; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">/s/
    Kevin Tang</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; width: 20%">&nbsp;</TD>
    <TD STYLE="padding-bottom: 1pt; width: 52%; text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="padding-left: 9pt; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang, Manager</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border-bottom: Black 1pt solid; width: 48%; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">/s/
    Kevin Tang</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; width: 52%; text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

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    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: right"><B>Exhibit&nbsp;99.1</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><B>JOINT FILING AGREEMENT</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left; text-indent: 0.25in">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;In accordance
with Rule&nbsp;13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, the undersigned agree to the joint filing of
a Statement on Schedule&nbsp;13G (including any and all amendments thereto) with respect to the Common Stock, $0.01 par value per
share, of Heron Therapeutics, Inc. and further agree to the filing of this agreement as an exhibit thereto. In addition, each party
to this Agreement expressly authorizes each other party to this Agreement to file on its behalf any and all amendments to such
Statement on Schedule&nbsp;13G.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
<TR>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Date: November
    19, 2020</FONT></TD>
    <TD COLSPAN="3" STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>TANG CAPITAL PARTNERS, LP</B></FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="width: 46%; text-align: left">&nbsp;</TD>
    <TD STYLE="width: 6%; text-align: left">&nbsp;</TD>
    <TD STYLE="width: 6%; text-align: left">&nbsp;</TD>
    <TD STYLE="width: 32%; text-align: left">&nbsp;</TD>
    <TD STYLE="width: 10%; text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">By:&nbsp;&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management, LLC &nbsp;</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Its:&nbsp;&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">General Partner&nbsp;</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: left">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">By:&nbsp;&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">/s/ Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Name:&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang&nbsp;</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Title:&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Manager&nbsp;</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD COLSPAN="5" STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: left">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>TANG CAPITAL MANAGEMENT, LLC</B></FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">By:&nbsp;&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">/s/ Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Name:&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang&nbsp;</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Title:&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Manager&nbsp;</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="vertical-align: top; text-align: left">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD COLSPAN="3" STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">/s/ Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="vertical-align: top; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Name:&nbsp;&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang&nbsp;</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center">Page 10 of 10 Pages</P>

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