XML 39 R27.htm IDEA: XBRL DOCUMENT v3.20.4
Income Taxes (Tables)
12 Months Ended
Dec. 31, 2020
Income Tax Disclosure [Abstract]  
Schedule of Components of Income Tax Expense (Benefit)

The difference between the provision for income taxes and income taxes computed using the effective U.S. federal statutory rate is as follows (in thousands):

 

 

 

December 31,

 

 

 

2020

 

 

2019

 

 

2018

 

Tax at statutory federal rate

 

$

(47,728

)

 

$

(42,997

)

 

$

(37,557

)

State tax, net of federal benefit

 

 

(8,218

)

 

 

(9,823

)

 

 

(6,527

)

Research and development credits

 

 

(4,327

)

 

 

(4,855

)

 

 

(4,775

)

Stock-based compensation expense

 

 

4,675

 

 

 

2,906

 

 

 

(2,059

)

Non-deductible compensation

 

 

1,455

 

 

 

4,720

 

 

 

901

 

Change in valuation allowance

 

 

53,621

 

 

 

49,479

 

 

 

50,834

 

Other

 

 

522

 

 

 

570

 

 

 

(817

)

Provision for income taxes

 

$

 

 

$

 

 

$

 

Schedule of Deferred Tax Assets and Liabilities

Deferred income tax assets and liabilities arising from differences between accounting for financial statement purposes and tax purposes, less valuation allowance at year-end are as follows (in thousands):

 

 

 

December 31,

 

 

 

2020

 

 

2019

 

Deferred tax assets:

 

 

 

 

 

 

 

 

Net operating loss carryforward

 

$

251,971

 

 

$

210,301

 

Research and development credits

 

 

49,683

 

 

 

42,490

 

Stock-based compensation

 

 

20,211

 

 

 

15,628

 

Lease liabilities

 

 

4,330

 

 

 

3,487

 

Other

 

 

3,777

 

 

 

3,818

 

Total gross deferred tax assets

 

 

329,972

 

 

 

275,724

 

Deferred tax liabilities:

 

 

 

 

 

 

 

 

Right-of-use lease assets

 

 

(4,014

)

 

 

(3,385

)

Total gross deferred tax liabilities

 

 

(4,014

)

 

 

(3,385

)

Valuation allowance

 

 

(325,958

)

 

 

(272,339

)

Net deferred tax assets

 

$

 

 

$

 

Summary of Unrecognized Tax Benefits

A reconciliation of our unrecognized tax benefits is as follows (in thousands):

 

 

 

Year Ended December 31,

 

 

 

2020

 

 

2019

 

 

2018

 

Balance at beginning of year

 

$

4,784

 

 

$

2,385

 

 

$

120

 

Additions for tax positions of prior years

 

 

341

 

 

 

147

 

 

 

 

Additions based on tax positions related to current year

 

 

2,281

 

 

 

2,252

 

 

 

2,265

 

Balance at end of year

 

$

7,406

 

 

$

4,784

 

 

$

2,385