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v3.21.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2021 | Jun. 30, 2020
Operating activities: |  |
Net loss | $ (113,629) | $ (106,769)
Adjustments to reconcile net loss to net cash used for operating activities: |  |
Stock-based compensation expense | 22,727 | 23,088
Depreciation and amortization | 1,473 | 1,366
Amortization of debt discount | 785 | 645
Amortization of premium (accretion of discount) on short-term investments | 178 | (82)
Impairment of property and equipment | 190 | 53
Change in operating assets and liabilities: |  |
Accounts receivable | (765) | 2,377
Inventory | (895) | (16,474)
Prepaid expenses and other assets | (1,783) | 10,136
Accounts payable | 10,717 | 15,700
Accrued clinical and manufacturing liabilities | (26,055) | (4,441)
Accrued payroll and employee liabilities | 84 | (4,055)
Other accrued liabilities | 2,043 | (11,756)
Net cash used for operating activities | (104,930) | (90,212)
Investing activities: |  |
Purchases of short-term investments | (62,046) | (66,915)
Maturities and sales of short-term investments | 98,500 | 166,825
Purchases of property and equipment | (1,101) | (3,687)
Net cash provided by investing activities | 35,353 | 96,223
Financing activities: |  |
Net proceeds from convertible note financing | 148,982 |
Proceeds from issuance of common stock under equity incentive plan | 5,101 | 1,309
Proceeds from purchases under the Employee Stock Purchase Plan | 1,529 | 1,507
Proceeds from warrant exercises |  | 3
Net cash provided by financing activities | 155,612 | 2,819
Net increase in cash and cash equivalents | 86,035 | 8,830
Cash and cash equivalents at beginning of year | 105,138 | 71,898
Cash and cash equivalents at end of period | $ 191,173 | $ 80,728

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- Definition Amount of cash inflow from sale, maturity, prepayment and call of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3151-108585 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3179-108585 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 45 -Paragraph 11 -URI http://asc.fasb.org/extlink&oid=121553693&loc=d3e26853-111562 + Details
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- Definition The cash inflow associated with the amount received from holders exercising their stock warrants. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3255-108585 + Details
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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3602-108585 + Details
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