<SEC-DOCUMENT>0001214659-21-001973.txt : 20210216
<SEC-HEADER>0001214659-21-001973.hdr.sgml : 20210216
<ACCEPTANCE-DATETIME>20210216161555
ACCESSION NUMBER:		0001214659-21-001973
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20210216
DATE AS OF CHANGE:		20210216
GROUP MEMBERS:		KEVIN TANG
GROUP MEMBERS:		TANG CAPITAL MANAGEMENT, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
		CENTRAL INDEX KEY:			0000818033
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				942875566
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-39444
		FILM NUMBER:		21638643

	BUSINESS ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		8582514400

	MAIL ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
		DATE OF NAME CHANGE:	20010511

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TANG CAPITAL PARTNERS LP
		CENTRAL INDEX KEY:			0001191935
		IRS NUMBER:				680517277
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		4747 EXECUTIVE DRIVE
		STREET 2:		SUITE 210
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		858-200-3830

	MAIL ADDRESS:	
		STREET 1:		4747 EXECUTIVE DRIVE
		STREET 2:		SUITE 210
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>f29212sc13ga1.htm
<DESCRIPTION>AMEDMENT NO. 1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>

</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0"></P>


<P STYLE="font: 14pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Securities
and Exchange Commission</B></FONT></P>

<P STYLE="font: 12pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="font-variant: small-caps"><B>Washington,
DC 20549</B></FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman; margin: 0pt 0; text-align: center"> <B>SCHEDULE 13G/A</B> </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="font-variant: small-caps"><B></B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="font-variant: small-caps"><B>Under
the Securities Exchange Act of 1934</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"> <FONT STYLE="font-variant: small-caps"><B>(Amendment
No. 1)*</B></FONT> </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 24pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B><U>Heron Therapeutics, Inc.</U></B></P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Name of Issuer)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><B><U>Common Stock, par value $0.01 per share</U></B></P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Title of Class of Securities)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center"><B><U>427746102</U></B></P>

<P STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(CUSIP Number)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><B><U></U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"> <B><U>December 31, 2020</U></B> </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center">(Date of Event Which Requires Filing of This Statement)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: justify">Check the appropriate box to designate the rule pursuant
to which this Schedule is filed:</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><tr style="vertical-align: top">
<td style="width: 36pt"></td><td style="width: 36pt; text-align: left"><font style="font-family: Times New Roman, Times, Serif">&#9744;</font></td><td>Rule 13d-1(b)</td>
</tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><tr style="vertical-align: top">
<td style="width: 36pt"></td><td style="width: 36pt; text-align: left"><font style="font-family: Wingdings">&yacute;</font></td><td>Rule 13d-1(c)</td>
</tr></table>

<p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</p>

<table cellpadding="0" cellspacing="0" style="font: 10pt Times New Roman, Times, Serif; margin-top: 0; margin-bottom: 0; width: 100%"><tr style="vertical-align: top">
<td style="width: 36pt"></td><td style="width: 36pt; text-align: left"><font style="font-family: Times New Roman, Times, Serif">&#9744;</font></td><td>Rule 13d-1(d)</td>
</tr></table>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: justify">*The remainder of this cover page shall be filled out
for a reporting person&rsquo;s initial filing on this form with respect to the subject class of securities, and for any subsequent
amendment containing information which would alter the disclosures provided in a prior cover page.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: justify">The information required in the remainder of this cover
page shall not be deemed to be &ldquo;filed&rdquo; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&ldquo;Act&rdquo;)
or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,
see the Notes).</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 12pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; border-bottom: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 1 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->1<!-- Field: /Sequence --> of 8 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 39%">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><B>CUSIP No. 427746102</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P></TD>
    <TD STYLE="width: 30%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt"><B>13G</B></FONT></TD>
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 31%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>Page 2 of 8 Pages</B></FONT></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>1</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">NameS of Reporting
        Persons<BR>
        I.R.S. Identification NOS. of Above Persons (ENTITIES ONLY)</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">TANG CAPITAL PARTNERS,
        LP</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt; width: 6%"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>2</B></FONT></TD>
    <TD STYLE="text-align: left; font-size: 12pt; width: 84%"><FONT STYLE="font-size: 10pt; text-transform: uppercase">Check
the Appropriate Box if a Member of a Group*</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: left; font-size: 12pt; width: 10%">        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;<font style="font-family: Wingdings">&uml;</font></p>
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;<font style="font-family: Wingdings">&yacute;</font></p></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>3</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; background-color: #CCCCCC">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">SEC Use Only</FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>4</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Citizenship or Place
        of Organization</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">DELAWARE</FONT></P>

</TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="vertical-align: bottom; width: 24%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Number of</FONT></TD>
    <TD STYLE="vertical-align: top; width: 7%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>5</B></FONT></TD>
    <TD STYLE="vertical-align: top; width: 69%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">Shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">BENEFICIALLY<BR>
        Owned by</FONT></P></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>6</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Each Reporting <BR>
Person with</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>7</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt">&nbsp;</TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>8</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 7%; border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>9</B></FONT></TD>
    <TD STYLE="width: 93%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Aggregate Amount
        Beneficially Owned by each Reporting Person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>10</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Check Box if the
        Aggregate Amount in Row (9) excludes certain shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Wingdings; margin: 0pt 34.7pt 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&uml;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>11</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Percent of Class
        represented by amount in row 9</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7.8%</FONT> </P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>12</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">type of reporting
        person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">pN</FONT></P>

</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 2 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->2<!-- Field: /Sequence --> of 8 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>


<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 39%">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><B>CUSIP No. 427746102</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P></TD>
    <TD STYLE="width: 30%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt"><B>13G</B></FONT></TD>
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 31%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>Page
    3 of 8 Pages</B></FONT></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>1</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">NameS of Reporting
        Persons<BR>
        I.R.S. Identification NOS. of Above Persons (ENTITIES ONLY)</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Tang Capital Management,
        LLC</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt; width: 6%"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>2</B></FONT></TD>
    <TD STYLE="text-align: left; font-size: 12pt; width: 84%"><FONT STYLE="font-size: 10pt; text-transform: uppercase">Check
the Appropriate Box if a Member of a Group*</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: left; font-size: 12pt; width: 10%">        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;<font style="font-family: Wingdings">&uml;</font></p>
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;<font style="font-family: Wingdings">&yacute;</font></p></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>3</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; background-color: #CCCCCC">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">SEC Use Only</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>4</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Citizenship or Place
        of Organization</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">DELAWARE</FONT></P>

</TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="vertical-align: bottom; width: 24%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Number of</FONT></TD>
    <TD STYLE="vertical-align: top; width: 7%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>5</B></FONT></TD>
    <TD STYLE="vertical-align: top; width: 69%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">Shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">BENEFICIALLY<BR>
        Owned by</FONT></P></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>6</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Each Reporting <BR>
Person with</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>7</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">0</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt">&nbsp;</TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>8</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 7%; border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>9</B></FONT></TD>
    <TD STYLE="width: 93%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Aggregate Amount
        Beneficially Owned by each Reporting Person </FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>10</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Check Box if the
        Aggregate Amount in Row (9) excludes certain shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Wingdings; margin: 0pt 34.7pt 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&uml;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>11</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Percent of Class
        represented by amount in row 9</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7.8%</FONT> </P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>12</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">type of reporting
        person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">OO</FONT></P>

</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 3 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->3<!-- Field: /Sequence --> of 8 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 39%">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><B>CUSIP No. 427746102</B></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P></TD>
    <TD STYLE="width: 30%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt"><B>13G</B></FONT></TD>
    <TD STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; width: 31%; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt"><B>Page
    4 of 8 Pages</B></FONT></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>1</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">NameS of Reporting
        Persons<BR>
        I.R.S. Identification NOS. of Above Persons (ENTITIES ONLY)</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Kevin Tang</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt; width: 6%"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>2</B></FONT></TD>
    <TD STYLE="text-align: left; font-size: 12pt; width: 84%"><FONT STYLE="font-size: 10pt; text-transform: uppercase">Check
the Appropriate Box if a Member of a Group*</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: left; font-size: 12pt; width: 10%">        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a)&nbsp;&nbsp;<font style="font-family: Wingdings">&uml;</font></p>
        <p style="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(b)&nbsp;&nbsp;<font style="font-family: Wingdings">&yacute;</font></p></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>3</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; background-color: #CCCCCC">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">SEC Use Only</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>4</B></FONT></TD>
    <TD COLSPAN="2" STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Citizenship or Place
        of Organization</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">united states</FONT></P>

</TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
    <TD STYLE="vertical-align: bottom; width: 24%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Number of</FONT></TD>
    <TD STYLE="vertical-align: top; width: 7%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>5</B></FONT></TD>
    <TD STYLE="vertical-align: top; width: 69%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">3,445</FONT> </P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">Shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase">BENEFICIALLY<BR>
        Owned by</FONT></P></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>6</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Voting Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 10pt; text-transform: uppercase">Each Reporting <BR>
Person with</FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>7</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Sole Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">3,445</FONT> </P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt">&nbsp;</TD>
    <TD STYLE="border-right: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>8</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Shared Dispositive
        Power</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,635,655</FONT> </P></TD></TR>
</TABLE>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 7%; border: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>9</B></FONT></TD>
    <TD STYLE="width: 93%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Aggregate Amount
        Beneficially Owned by each Reporting Person </FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7,639,100</FONT> </P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>10</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Check Box if the
        Aggregate Amount in Row (9) excludes certain shares</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Wingdings; margin: 0pt 34.7pt 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&uml;</FONT></P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>11</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">Percent of Class
        represented by amount in row 9</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"> <FONT STYLE="text-transform: uppercase">7.8%</FONT> </P>

</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid; border-left: Black 1pt solid; text-align: center; font-size: 12pt"><FONT STYLE="font-family: Times New Roman; font-size: 18pt; text-transform: uppercase"><B>12</B></FONT></TD>
    <TD STYLE="border-right: Black 1pt solid; border-bottom: Black 1pt solid">
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">type of reporting
        person</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>
        <P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left"><FONT STYLE="text-transform: uppercase">IN</FONT></P>

</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 4 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->4<!-- Field: /Sequence --> of 8 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 1(a).</B></TD><TD STYLE="text-align: left">Name of Issuer:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left; text-indent: 1in">Heron Therapeutics, Inc., a Delaware corporation
(the &ldquo;Issuer&rdquo;)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 1(b).</B></TD><TD STYLE="text-align: left">Address of Issuer&rsquo;s Principal Executive Offices:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left; text-indent: 1in">4242 Campus Point Court, Suite 200, San
Diego, CA 92121</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(a).</B></TD><TD STYLE="text-align: left">Name of Person Filing:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">This Statement on Schedule 13G (this &ldquo;Statement&rdquo;)
is filed by Tang Capital Partners, LP (&ldquo;Tang Capital Partners&rdquo;); Tang Capital Management, LLC, the general partner
of Tang Capital Partners (&ldquo;Tang Capital Management&rdquo;); and Kevin Tang, the manager of Tang Capital Management.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(b).</B></TD><TD STYLE="text-align: left"><B>A</B>ddress of Principal Business Office or, if none, Residence:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">4747 Executive Drive, Suite 210, San Diego, CA 92121</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(c).</B></TD><TD STYLE="text-align: left">Citizenship:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Tang Capital Partners is a Delaware limited partnership.
Tang Capital Management is a Delaware limited liability company. Mr. Tang is a United States citizen.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(d).</B></TD><TD STYLE="text-align: left">Title of Class of Securities:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">Common Stock, par value $0.01 per share (the &ldquo;Common
Stock&rdquo;)</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(e).</B></TD><TD STYLE="text-align: left">CUSIP Number: 427746102</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 3.</B></TD><TD STYLE="text-align: left"><B>Not applicable.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 4.</B></TD><TD STYLE="text-align: left"><B>Ownership.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 45pt"></TD><TD STYLE="width: 27pt">(a)</TD><TD STYLE="text-align: left">Amount Beneficially Owned:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1in; text-align: left"> <B>Tang Capital Partners.</B>
Tang Capital Partners is the beneficial owner of <FONT STYLE="text-transform: uppercase">7,635,655 </FONT>shares of the Issuer&rsquo;s
Common Stock, which are currently issuable upon conversion of the Notes (defined below). </P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1in; text-align: left">Tang Capital Partners shares voting
and dispositive power over such shares with Tang Capital Management and Kevin Tang.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 1in; text-align: left"> Tang Capital Partners, LP is the owner of $6,108,524 principal amount of Senior Secured Convertible Notes due 2021 (the &ldquo;Notes&rdquo;), which may
be converted into Common Stock at a conversion rate of 1,250 shares per $1,000 principal amount of Notes. </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"> <B>Tang Capital Management.</B> Tang Capital
Management is the beneficial owner of <FONT STYLE="text-transform: uppercase">7,635,655 </FONT>shares of the Issuer&rsquo;s Common
Stock, which are currently issuable upon conversion of the Notes (defined below). </P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"> &nbsp; </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"> Tang Capital Management shares voting and dispositive
power over such shares with Tang Capital Partners and Kevin Tang. </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 5 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->5<!-- Field: /Sequence --> of 8 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"> Tang Capital Partners, LP is the owner of $6,108,524
principal amount of Senior Secured Convertible Notes due 2021 (the &ldquo;Notes&rdquo;), which may be converted into Common Stock
at a conversion rate of 1,250 shares per $1,000 principal amount of Notes. </P>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"> &nbsp; </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"> <B>Kevin Tang.</B> Kevin Tang is the beneficial
owner of <FONT STYLE="text-transform: uppercase">7,635,655 </FONT>shares of the Issuer&rsquo;s Common Stock, which are currently
issuable upon conversion of the Notes (defined below), and 3,445 shares owned by Kevin Tang&rsquo;s minor children under the Uniform
Transfers to Minors Act, for which Kevin Tang serves as trustee. </P>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"> &nbsp; </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"> Kevin Tang shares voting and dispositive power
over such shares with Tang Capital Management and Tang Capital Partners. </P>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"> &nbsp; </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"> Tang Capital Partners, LP is the owner of $6,108,524
principal amount of Senior Secured Convertible Notes due 2021 (the &ldquo;Notes&rdquo;), which may be converted into Common Stock
at a conversion rate of 1,250 shares per $1,000 principal amount of Notes. </P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left"> The mailing address of all of the foregoing
persons and entities is c/o Tang Capital Management, LLC, 4747 Executive Drive, Suite 210, San Diego, CA 92121. </P>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 1in; text-align: left">The percentages used herein are based on 98,490,909
shares of Common Stock outstanding (90,855,254 reported to be issued and outstanding as of October 29, 2020, as set forth in the
Company&rsquo;s Quarterly Report on Form 10-Q that was filed with the SEC on November 5, 2020, plus an additional 7,635,655 shares
of Common Stock currently issuable upon conversion of the Notes).</P>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 45pt"></TD><TD STYLE="width: 27pt">(b)</TD><TD STYLE="text-align: left">Percent of Class:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 80%; border-collapse: collapse; margin-left: 1in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7.8%</FONT> </TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management</FONT></TD>
    <TD STYLE="text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7.8%</FONT> </TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"> 7.8% </TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 45pt"></TD><TD STYLE="width: 27pt">(c)</TD><TD STYLE="text-align: left">Number of shares as to which such person has:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(i)</TD><TD STYLE="text-align: left">sole power to vote or to direct the vote:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">3,445 shares</FONT> </TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(ii)</TD><TD STYLE="text-align: left">shared power to vote or to direct the vote:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7,635,655 shares</FONT> </TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7,635,655 shares</FONT> </TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7,635,655 shares</FONT> </TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(iii)</TD><TD STYLE="text-align: left">sole power to dispose or to direct the disposition of:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">0 shares</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">3,445 shares</FONT> </TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in">(iv)</TD><TD STYLE="text-align: left">shared power to dispose or to direct the disposition of:</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 75%; border-collapse: collapse; margin-left: 1.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Partners </FONT></TD>
    <TD STYLE="width: 2in; text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7,635,655 shares</FONT> </TD></TR>
<TR STYLE="vertical-align: top; background-color: White">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Tang Capital Management </FONT></TD>
    <TD STYLE="text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7,635,655 shares</FONT> </TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="white-space: nowrap; text-align: left"><FONT STYLE="font-family: Times New Roman; font-size: 10pt">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left"> <FONT STYLE="font-family: Times New Roman; font-size: 10pt">7,635,655 shares</FONT> </TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 6 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->6<!-- Field: /Sequence --> of 8 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 5.</B></TD><TD STYLE="text-align: left"><B>Ownership of Five Percent or Less of a Class.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 45.35pt; text-align: left"><FONT STYLE="font-family: Times New Roman">If this
statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner
of more than five percent of the class of securities, check the following: </FONT><FONT STYLE="font: 10pt Wingdings">o</FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 6.</B></TD><TD STYLE="text-align: left"><B>Ownership of More than Five Percent on Behalf of Another Person.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 7.</B></TD><TD STYLE="text-align: left"><B>Identification and Classification of the Subsidiary Which Acquired the Security Being Reported
on by the Parent Holding Company.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 8.</B></TD><TD STYLE="text-align: left"><B>Identification and Classification of Members of the Group.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 9.</B></TD><TD STYLE="text-align: left"><B>Notice of Dissolution of Group.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">Not applicable.</P>


<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 45pt"><B>Item 10.</B></TD><TD STYLE="text-align: left"><B>Certification.</B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0 0pt 45pt; text-align: left">By signing below I certify that, to the best of
my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect
of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with
or as a participant in any transaction having that purpose or effect.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 7 -->
    <DIV STYLE="margin-top: 8pt; margin-bottom: 6pt; border-bottom: Black 2px solid"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font-size: 10pt"><TR STYLE="vertical-align: top; text-align: left"><TD STYLE="width: 33%">&nbsp;</TD><TD STYLE="width: 34%; text-align: center">Page <!-- Field: Sequence; Type: Arabic; Name: PageNo -->7<!-- Field: /Sequence --> of 8 pages</TD><TD STYLE="width: 33%; text-align: right">&nbsp;</TD></TR></TABLE></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 8pt"><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%"><TR><TD STYLE="text-align: left; width: 100%"><FONT STYLE="font-size: 8pt">&nbsp;</FONT></TD></TR></TABLE></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Signature</B></FONT></P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0; text-align: left">After reasonable inquiry and to the best of my knowledge
and belief, I certify that the information set forth in this statement is true, complete and correct.</P>

<P STYLE="font: 10pt Times New Roman; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: left">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Date:</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; width: 45%; text-align: left"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"> February
                                         16, 2021 </P></TD>
    <TD STYLE="width: 50%; text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">TANG CAPITAL PARTNERS, LP</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">By:&nbsp;&nbsp;</FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Tang Capital Management, LLC, its General Partner</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">By:</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">/s/ Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"></FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Kevin Tang, Manager</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="3" STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">TANG CAPITAL MANAGEMENT, LLC</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">By:</FONT></TD>
    <TD STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">/s/ Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif"></FONT></TD>
    <TD STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Kevin Tang, Manager</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">/s/ Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" STYLE="text-align: left"><FONT STYLE="font: 10pt Times New Roman, Times, Serif">Kevin Tang</FONT></TD>
    <TD STYLE="text-align: left">&nbsp;</TD></TR>
</TABLE>


<P STYLE="margin: 0"></P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin-top: 0; text-align: center; margin-bottom: 0">Page 8  of 8  Pages</P>

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="border-top: Black 2px solid; font-size: 1pt">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="margin: 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
