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v3.22.1

Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands | Total | Common Stock | Additional Paid-In Capital | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit
--- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2020 | $ 236,492 | $ 913 | $ 1,628,070 | $ 257 | $ (1,392,748)
Balance (in shares) at Dec. 31, 2020 |  | 91,310 |  |  |
Conversion benefit included in Convertible Notes issued | 114 |  | 114 |  |
Issuance of common stock under equity incentive plan | 883 | $ 1 | 882 |  |
Issuance of common stock under equity incentive plan (in shares) |  | 97 |  |  |
Stock-based compensation expense | 11,486 |  | 11,486 |  |
Net loss | (52,614) |  |  |  | (52,614)
Net unrealized gain (loss) on short-term investments | (136) |  |  | (136) |
Comprehensive loss | (52,750) |  |  |  |
Balance at Mar. 31, 2021 | 196,225 | $ 914 | 1,640,552 | 121 | (1,445,362)
Balance (in shares) at Mar. 31, 2021 |  | 91,407 |  |  |
Balance at Dec. 31, 2021 | 77,570 | $ 1,020 | 1,689,987 | (6) | (1,613,431)
Balance (in shares) at Dec. 31, 2021 |  | 102,005 |  |  |
Issuance of common stock under equity incentive plan | (637) | $ 1 | (638) |  |
Issuance of common stock under equity incentive plan (in shares) |  | 138 |  |  |
Stock-based compensation expense | 10,915 |  | 10,915 |  |
Net loss | (63,888) |  |  |  | (63,888)
Net unrealized gain (loss) on short-term investments | (2) |  |  | (2) |
Comprehensive loss | (63,890) |  |  |  |
Balance at Mar. 31, 2022 | $ 23,958 | $ 1,021 | $ 1,700,264 | $ (8) | $ (1,677,319)
Balance (in shares) at Mar. 31, 2022 |  | 102,143 |  |  |

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