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Inventory - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Inventory [Line Items]          
Total inventory $ 52,239   $ 52,239   $ 48,382
ZYNRELEF          
Inventory [Line Items]          
Total inventory 36,200   36,200   23,600
Cost of product sales, charges 2,000   4,500    
SUSTOL          
Inventory [Line Items]          
Total inventory 2,600   2,600   1,700
Cost of product sales, charges   $ 400   $ 3,500  
CINVANTI          
Inventory [Line Items]          
Total inventory $ 13,400   $ 13,400   $ 23,100