    <SEC-DOCUMENT>0001564590-22-031836-index.html : 20220919
    <SEC-HEADER>0001564590-22-031836.hdr.sgml : 20220919
    <ACCEPTANCE-DATETIME>20220919080054
    ACCESSION NUMBER:		0001564590-22-031836
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		37
    CONFORMED PERIOD OF REPORT:	20220916
    ITEM INFORMATION:		Other Events
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20220919
    DATE AS OF CHANGE:		20220919

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
    		CENTRAL INDEX KEY:			0000818033
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				942875566
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33221
    		FILM NUMBER:		221249427

    	BUSINESS ADDRESS:
    		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		8582514400

    	MAIL ADDRESS:
    		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
    		DATE OF NAME CHANGE:	20010511

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
    		DATE OF NAME CHANGE:	19920703
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>hrtx-8k_20220916.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: hrtx-8k_20220916.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>hrtx-ex991_15.htm
    <DESCRIPTION>EX-99.1
    <TEXT>
    Document 2 - file: hrtx-ex991_15.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2
    <SEQUENCE>3
    <FILENAME>hrtx-ex992_85.htm
    <DESCRIPTION>EX-99.2
    <TEXT>
    Document 3 - file: hrtx-ex992_85.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>slide-y43ambvyrhs.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: slide-y43ambvyrhs.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>slide-2pwqlk2m231.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: slide-2pwqlk2m231.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>slide-rgevzwej41z.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: slide-rgevzwej41z.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>slide-p2c5jrmn0oe.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: slide-p2c5jrmn0oe.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>slide-mtkp4orsamr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: slide-mtkp4orsamr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>gpwkv1yxmhkx000001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: gpwkv1yxmhkx000001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>slide-0xucslgbw53.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: slide-0xucslgbw53.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>slide-44tzs4cl4m4.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: slide-44tzs4cl4m4.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>slide-qfjqbkkj5jw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: slide-qfjqbkkj5jw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>slide-rqu01irradx.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: slide-rqu01irradx.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>slide-y1qkm22erkz.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: slide-y1qkm22erkz.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>slide-v2s04e3uzwb.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: slide-v2s04e3uzwb.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>slide-3qemukqv2id.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: slide-3qemukqv2id.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>slide-dpipcj42lqq.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: slide-dpipcj42lqq.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>slide-3uzpuxwbxuy.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: slide-3uzpuxwbxuy.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>slide-xodglnd2anu.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: slide-xodglnd2anu.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>slide-fbfmz4kvbrw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: slide-fbfmz4kvbrw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>slide-slalnzyvg4h.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 21 - file: slide-slalnzyvg4h.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>slide-5t3osoho3ni.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 22 - file: slide-5t3osoho3ni.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>slide-3hwsgnbgdh0.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 23 - file: slide-3hwsgnbgdh0.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>slide-demrtq0u5f5.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 24 - file: slide-demrtq0u5f5.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>slide-z1mqdvywxb0.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 25 - file: slide-z1mqdvywxb0.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>slide-ek1bpfowv4h.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 26 - file: slide-ek1bpfowv4h.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.SCH
    <SEQUENCE>27
    <FILENAME>hrtx-20220916.xsd
    <DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA
    <TEXT>
    Document 27 - file: hrtx-20220916.xsd

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.LAB
    <SEQUENCE>28
    <FILENAME>hrtx-20220916_lab.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE
    <TEXT>
    Document 28 - file: hrtx-20220916_lab.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.PRE
    <SEQUENCE>29
    <FILENAME>hrtx-20220916_pre.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE
    <TEXT>
    Document 29 - file: hrtx-20220916_pre.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>30
    <FILENAME>R1.htm
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 30 - file: R1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>31
    <FILENAME>hrtx-8k_20220916_htm.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 31 - file: hrtx-8k_20220916_htm.html

    Document 31 - RAW XML: hrtx-8k_20220916_htm.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EXCEL
    <SEQUENCE>32
    <FILENAME>Financial_Report.xlsx
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 32 - file: Financial_Report.xlsx

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>33
    <FILENAME>Show.js
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 33 - file: Show.js

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>34
    <FILENAME>report.css
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 34 - file: report.css

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>35
    <FILENAME>FilingSummary.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 35 - file: FilingSummary.html

    Document 35 - RAW XML: FilingSummary.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>JSON
    <SEQUENCE>37
    <FILENAME>MetaLinks.json
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 37 - file: MetaLinks.json

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>ZIP
    <SEQUENCE>38
    <FILENAME>0001564590-22-031836-xbrl.zip
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 38 - file: 0001564590-22-031836-xbrl.zip

    </DOCUMENT>
    </SEC-DOCUMENT>