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Balance Sheet Details - Additional Information (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Debt securities, impairment losses | $ 0 | $ 0
Debt securities, available-for-sale, unrealized gain (loss) | (13,000) | (263,000)
Debt securities, available-for-sale, realized gain (loss) | 0 | 0
Inventory | 54,573,000 | 48,382,000
Depreciation and amortization | 2,889,000 | 3,021,000
Construction in Progress, Gross | 5,400,000 | 15,900,000
ZYNRELEF |  |
Inventory | 30,900,000 | 23,600,000
Cost of product sales, charges | 8,900,000 |
SUSTOL |  |
Inventory | 2,600,000 | 1,700,000
Cost of product sales, charges |  | 3,800,000
CINVANTI |  |
Inventory | 19,900,000 | $ 23,100,000
APONVIE |  |
Inventory | $ 1,200,000 |

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