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Balance Sheet Details - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Debt securities, impairment losses $ 0 $ 0
Debt securities, available-for-sale, unrealized gain (loss) (13,000) (263,000)
Debt securities, available-for-sale, realized gain (loss) 0 0
Inventory 54,573,000 48,382,000
Depreciation and amortization 2,889,000 3,021,000
Construction in Progress, Gross 5,400,000 15,900,000
ZYNRELEF    
Inventory 30,900,000 23,600,000
Cost of product sales, charges 8,900,000  
SUSTOL    
Inventory 2,600,000 1,700,000
Cost of product sales, charges   3,800,000
CINVANTI    
Inventory 19,900,000 $ 23,100,000
APONVIE    
Inventory $ 1,200,000