    <SEC-DOCUMENT>0000950170-23-016047-index.html : 20230501
    <SEC-HEADER>0000950170-23-016047.hdr.sgml : 20230501
    <ACCEPTANCE-DATETIME>20230501091034
    ACCESSION NUMBER:		0000950170-23-016047
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20221231
    FILED AS OF DATE:		20230501
    DATE AS OF CHANGE:		20230501
    EFFECTIVENESS DATE:		20230501

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
    		CENTRAL INDEX KEY:			0000818033
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				942875566
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33221
    		FILM NUMBER:		23870540

    	BUSINESS ADDRESS:
    		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		8582514400

    	MAIL ADDRESS:
    		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
    		DATE OF NAME CHANGE:	20010511

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
    		DATE OF NAME CHANGE:	19920703
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>hrtx_ars_2023.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: hrtx_ars_2023.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>