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Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Balance at Dec. 31, 2021 $ 77,570 $ 1,020 $ 1,689,987 $ (6) $ (1,613,431)
Balance (in shares) at Dec. 31, 2021   102,005      
Issuance of common stock under equity incentive plan (637) $ 1 (638)    
Issuance of common stock under equity incentive plan (in shares)   138      
Stock-based compensation expense 10,915   10,915    
Net loss (63,888)       (63,888)
Net unrealized gain (loss) on short-term investments (2)     (2)  
Comprehensive loss (63,890)        
Balance at Mar. 31, 2022 23,958 $ 1,021 1,700,264 (8) (1,677,319)
Balance (in shares) at Mar. 31, 2022   102,143      
Balance at Dec. 31, 2022 13,572 $ 1,191 1,807,855 (19) (1,795,455)
Balance (in shares) at Dec. 31, 2022   119,155      
Issuance of common stock under equity incentive plan (208) $ 2 (210)    
Issuance of common stock under equity incentive plan (in shares)   125      
Stock-based compensation expense 7,947   7,947    
Net loss (32,768)       (32,768)
Net unrealized gain (loss) on short-term investments 28     28  
Comprehensive loss (32,740)        
Balance at Mar. 31, 2023 $ (11,429) $ 1,193 $ 1,815,592 $ 9 $ (1,828,223)
Balance (in shares) at Mar. 31, 2023   119,280