Inventory - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2022
Inventory [Line Items]
Total inventory	$ 42,007		$ 42,007		$ 54,573
ZYNRELEF
Inventory [Line Items]
Total inventory	12,700		12,700		30,900
Cost of product sales, charges	7,500	$ 2,000	20,300	$ 4,500
CINVANTI
Inventory [Line Items]
Total inventory	25,700		25,700		19,900
SUSTOL
Inventory [Line Items]
Total inventory	2,800		2,800		2,600
APONVIE
Inventory [Line Items]
Total inventory	$ 800		$ 800		$ 1,200