<SEC-DOCUMENT>0000921895-23-000348.txt : 20230208
<SEC-HEADER>0000921895-23-000348.hdr.sgml : 20230208
<ACCEPTANCE-DATETIME>20230208182600
ACCESSION NUMBER:		0000921895-23-000348
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20230130
FILED AS OF DATE:		20230208
DATE AS OF CHANGE:		20230208

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Morgan Adam
		CENTRAL INDEX KEY:			0001964335

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		23600435

	MAIL ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			VENKATARAMAN BALAJI
		CENTRAL INDEX KEY:			0001114916

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		23600436

	MAIL ADDRESS:	
		STREET 1:		FIRST HORIZON PHARMACEUTICAL CORP
		STREET 2:		660 HEMBREE PKWY STE 106
		CITY:			ROSWELL
		STATE:			GA
		ZIP:			30076

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Velan Capital Investment Management LP
		CENTRAL INDEX KEY:			0001848809
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		23600440

	BUSINESS ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009
		BUSINESS PHONE:		646-844-0037

	MAIL ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Velan Capital Master Fund LP
		CENTRAL INDEX KEY:			0001964356
		STATE OF INCORPORATION:			E9

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		23600439

	BUSINESS ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009
		BUSINESS PHONE:		646-844-0037

	MAIL ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Velan Capital Holdings LLC
		CENTRAL INDEX KEY:			0001964353

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		23600438

	BUSINESS ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009
		BUSINESS PHONE:		646-844-0037

	MAIL ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Velan Capital Management LLC
		CENTRAL INDEX KEY:			0001964355

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		23600437

	BUSINESS ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009
		BUSINESS PHONE:		646-844-0037

	MAIL ADDRESS:	
		STREET 1:		1055B POWERS PLACE
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30009

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
		CENTRAL INDEX KEY:			0000818033
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				942875566
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		8582514400

	MAIL ADDRESS:	
		STREET 1:		4242 CAMPUS POINT COURT, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
		DATE OF NAME CHANGE:	20010511

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form312927018val_02082023.xml
<DESCRIPTION>OWNERSHIP DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2023-01-30</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000818033</issuerCik>
        <issuerName>HERON THERAPEUTICS, INC. /DE/</issuerName>
        <issuerTradingSymbol>HRTX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001848809</rptOwnerCik>
            <rptOwnerName>Velan Capital Investment Management LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1055B POWERS PLACE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ALPHARETTA</rptOwnerCity>
            <rptOwnerState>GA</rptOwnerState>
            <rptOwnerZipCode>30009</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 2</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001964356</rptOwnerCik>
            <rptOwnerName>Velan Capital Master Fund LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>89 NEXUS WAY</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CAMANA BAY, GRAND CAYMAN</rptOwnerCity>
            <rptOwnerState>E9</rptOwnerState>
            <rptOwnerZipCode>KY1-9009</rptOwnerZipCode>
            <rptOwnerStateDescription>CAYMAN ISLANDS</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 2</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001964353</rptOwnerCik>
            <rptOwnerName>Velan Capital Holdings LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1055B POWERS PLACE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ALPHARETTA</rptOwnerCity>
            <rptOwnerState>GA</rptOwnerState>
            <rptOwnerZipCode>30009</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 2</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001964355</rptOwnerCik>
            <rptOwnerName>Velan Capital Management LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1055B POWERS PLACE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ALPHARETTA</rptOwnerCity>
            <rptOwnerState>GA</rptOwnerState>
            <rptOwnerZipCode>30009</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 2</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001114916</rptOwnerCik>
            <rptOwnerName>VENKATARAMAN BALAJI</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1055B POWERS PLACE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ALPHARETTA</rptOwnerCity>
            <rptOwnerState>GA</rptOwnerState>
            <rptOwnerZipCode>30009</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 2</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001964335</rptOwnerCik>
            <rptOwnerName>Morgan Adam</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1055B POWERS PLACE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ALPHARETTA</rptOwnerCity>
            <rptOwnerState>GA</rptOwnerState>
            <rptOwnerZipCode>30009</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>See Footnote 2</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $0.01 per share</value>
                <footnoteId id="F1"/>
                <footnoteId id="F2"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4500000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Velan Capital Master Fund LP</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">This Form 3 is filed jointly by Velan Capital Master Fund LP (&quot;Velan Master&quot;), Velan Capital Holdings LLC (&quot;Velan GP&quot;), Velan Capital Investment Management LP (&quot;Velan Capital&quot;), Velan Capital Management LLC (&quot;Velan IM GP&quot;), Balaji Venkataraman and Adam Morgan (collectively, the &quot;Reporting Persons&quot;).</footnote>
        <footnote id="F2">Each Reporting Person may be deemed to be a member of a Section 13(d) group that may be deemed to collectively beneficially own more than 10% of the Issuer's outstanding shares of Common Stock. Each Reporting Person disclaims beneficial ownership of the securities of the Issuer owned directly by the other members of the Section 13(d) group and this report shall not be deemed an admission that the Reporting Persons are the beneficial owners of such securities for purposes of Section 16 or for any other purpose. Further, each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein.</footnote>
        <footnote id="F3">Securities beneficially owned directly by Velan Master. As the general partner of Velan Master, Velan GP may be deemed to beneficially own the securities owned directly by Velan Master. As the investment manager of Velan Master, Velan Capital may be deemed to beneficially own the securities owned directly by Velan Master. As the general partner of Velan Capital, Velan IM GP may be deemed to beneficially own the securities owned directly by Velan Master. As the managing members of Velan GP and Velan IM GP, Messrs. Venkataraman and Morgan may be deemed to beneficially own the securities owned directly by Velan Master.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Velan Capital Master Fund LP, By: Velan Capital Holdings LLC, its general partner, By: /s/ Adam Morgan, managing member</signatureName>
        <signatureDate>2023-02-08</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Velan Capital Holdings LLC, By: /s/ Adam Morgan, managing member</signatureName>
        <signatureDate>2023-02-08</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Velan Capital Investment Management LP, By: Velan Capital Management LLC, its general partner, By: /s/ Adam Morgan, managing member</signatureName>
        <signatureDate>2023-02-08</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Velan Capital Management LLC, By: /s/ Adam Morgan, managing member</signatureName>
        <signatureDate>2023-02-08</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Balaji Venkataraman</signatureName>
        <signatureDate>2023-02-08</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Adam Morgan</signatureName>
        <signatureDate>2023-02-08</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
