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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2024
Income Tax Disclosure [Abstract]  
Schedule of Components of Income Tax Expense (Benefit)

The difference between the provision for income taxes and income taxes computed using the effective U.S. federal statutory rate is as follows (in thousands):

 

 

 

December 31,

 

 

 

2024

 

 

2023

 

 

2022

 

Tax at statutory federal rate

 

$

(2,852

)

 

$

(23,210

)

 

$

(38,225

)

State tax, net of federal benefit

 

 

1,513

 

 

 

(1,460

)

 

 

(13,898

)

Research and development credits

 

 

 

 

 

 

 

 

(3,531

)

Stock-based compensation expense

 

 

7,968

 

 

 

19,022

 

 

 

5,857

 

Non-deductible compensation

 

 

2,630

 

 

 

(4,682

)

 

 

2,104

 

Employee retention credit adjustment

 

 

 

 

 

 

 

 

(1,265

)

Change in valuation allowance

 

 

(10,392

)

 

 

7,556

 

 

 

46,452

 

Provision to return adjustment

 

 

285

 

 

 

3,008

 

 

 

 

Other

 

 

848

 

 

 

(234

)

 

 

2,506

 

Provision for income taxes

 

$

 

 

$

 

 

$

 

Schedule of Deferred Tax Assets and Liabilities

Deferred income tax assets and liabilities arising from differences between accounting for financial statement purposes and tax purposes, less valuation allowance at year-end are as follows (in thousands):

 

 

 

December 31,

 

 

 

2024

 

 

2023

 

Deferred tax assets:

 

 

 

 

 

 

Net operating loss carryforward

 

$

324,175

 

 

$

320,998

 

Research and development credits

 

 

59,168

 

 

 

59,417

 

Section 174 capitalized research and development

 

 

25,117

 

 

 

28,822

 

Stock-based compensation

 

 

5,323

 

 

 

15,413

 

Lease liabilities

 

 

762

 

 

 

1,471

 

Other

 

 

5,262

 

 

 

5,005

 

Total gross deferred tax assets

 

 

419,807

 

 

 

431,126

 

Deferred tax liabilities:

 

 

 

 

 

 

Right-of-use lease assets

 

 

(699

)

 

 

(1,362

)

Total gross deferred tax liabilities

 

 

(699

)

 

 

(1,362

)

Valuation allowance

 

 

(419,108

)

 

 

(429,764

)

Net deferred tax assets

 

$

 

 

$

 

 

Summary of Unrecognized Tax Benefits

A reconciliation of our unrecognized tax benefits is as follows (in thousands):

 

 

 

Year Ended December 31,

 

 

 

2024

 

 

2023

 

Balance at beginning of year

 

$

10,903

 

 

$

11,235

 

Decrease for tax positions of prior years

 

 

 

 

 

(332

)

Increase based on tax positions related to current year

 

 

 

 

 

 

Balance at end of year

 

$

10,903

 

 

$

10,903