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Balance Sheet Details - Additional Information (Details) - USD ($)
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Debt securities, impairment losses $ 0 $ 0  
Debt securities, available-for-sale, unrealized gain (loss) 0 (32,000)  
Debt securities, available-for-sale, realized gain (loss) 5,000 1,000 $ 0
Total inventory 53,160,000 42,110,000  
Depreciation and amortization 2,492,000 2,899,000 $ 2,889,000
Construction in Progress, Gross 2,600,000 6,300,000  
ZYNRELEF      
Total inventory 11,800,000 11,200,000  
Cost of product sales, charges 2,500,000 20,300,000  
SUSTOL      
Total inventory 3,200,000 4,100,000  
CINVANTI      
Total inventory 36,600,000 26,400,000  
APONVIE      
Total inventory $ 1,600,000 $ 400,000