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Accounting Policies (Tables) | 9 Months Ended
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Sep. 30, 2025
Accounting Policies [Abstract] |
Percentage of Net Product Sales and Accounts Receivable Balance | The following table includes the percentage of net product sales and accounts receivable balances for our three major Customers, each of which comprised 10% or more of our product sales:
|  | Net Product Sales |  |  | Accounts Receivable |
|  | Three Months Ended September 30, 2025 |  |  | Nine Months Ended September 30, 2025 |  |  | As of September 30, 2025 |
Customer A |  |  | 38.8 | % |  |  | 42.2 | % |  |  | 40.6 | %
Customer B |  |  | 33.6 | % |  |  | 33.5 | % |  |  | 33.4 | %
Customer C |  |  | 25.8 | % |  |  | 22.8 | % |  |  | 25.5 | %
Total |  |  | 98.2 | % |  |  | 98.5 | % |  |  | 99.5 | %
Schedule of Disaggregated Net Product Sales | The following table provides disaggregated net product sales (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
CINVANTI net product sales |  | $ | 23,955 |  |  | $ | 22,662 |  |  | $ | 73,841 |  |  | $ | 73,205 |
SUSTOL net product sales |  |  | 1,911 |  |  |  | 2,763 |  |  |  | 7,175 |  |  |  | 10,623 |
ZYNRELEF net product sales |  |  | 9,313 |  |  |  | 6,245 |  |  |  | 25,542 |  |  |  | 17,089 |
APONVIE net product sales |  |  | 3,034 |  |  |  | 1,140 |  |  |  | 7,758 |  |  |  | 2,587 |
Total net product sales |  | $ | 38,213 |  |  | $ | 32,810 |  |  | $ | 114,316 |  |  | $ | 103,504 |
Summary of Activity to Product Returns, Distributor Fees and Discounts, Rebates and Administrative Fees | The following table provides a summary of activity with respect to our product returns, distributor fees and discounts, rebates and administrative fees, which are included in other accrued liabilities on the condensed consolidated balance sheets (in thousands):
|  | Product Returns |  |  | Distributor Fees |  |  | Discounts, Rebates and Administrative Fees |  |  | Total |
Balance at December 31, 2024 |  | $ | 3,791 |  |  | $ | 5,883 |  |  | $ | 27,745 |  |  | $ | 37,419 |
Provision |  |  | 1,544 |  |  |  | 25,949 |  |  |  | 170,019 |  |  |  | 197,512 |
Payments/credits |  |  | (842 | ) |  |  | (25,264 | ) |  |  | (167,462 | ) |  |  | (193,568 | )
Balance at September 30, 2025 |  | $ | 4,493 |  |  | $ | 6,568 |  |  | $ | 30,302 |  |  | $ | 41,363 |
Common Stock Equivalents Excluded From Computation of Net Loss Per Share | Because we have incurred a net loss for the three and nine months ended September 30, 2025 and 2024, the following common stock equivalents were not included in the computation of net loss per share because their effect would be anti-dilutive (in thousands):
|  | As of September 30, |
|  | 2025 |  |  | 2024 |
Stock options outstanding |  |  | 28,888 |  |  |  | 26,156 |
Restricted stock units outstanding |  |  | 4,014 |  |  |  | 1,547 |
Warrants outstanding |  |  | 298 |  |  |  | 298 |
Shares of common stock underlying convertible notes outstanding |  |  | 19,444 |  |  |  | 9,819 |
Series A Preferred Stock convertible to common shares |  |  | 5,241 |  |  |  | — |

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