    <SEC-DOCUMENT>0001062993-22-012897-index.html : 20220518
    <SEC-HEADER>0001062993-22-012897.hdr.sgml : 20220518
    <ACCEPTANCE-DATETIME>20220518160728
    ACCESSION NUMBER:		0001062993-22-012897
    CONFORMED SUBMISSION TYPE:	4
    PUBLIC DOCUMENT COUNT:		2
    CONFORMED PERIOD OF REPORT:	20220516
    FILED AS OF DATE:		20220518
    DATE AS OF CHANGE:		20220518

    REPORTING-OWNER:

    	OWNER DATA:
    		COMPANY CONFORMED NAME:			LANCASTER RONNY B
    		CENTRAL INDEX KEY:			0001238960

    	FILING VALUES:
    		FORM TYPE:		4
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-16537
    		FILM NUMBER:		22939135

    	MAIL ADDRESS:
    		STREET 1:		ORASURE TECHNOLOGIES INC
    		STREET 2:		220 EAST FIRST STREET
    		CITY:			BETHLEHEM
    		STATE:			PA
    		ZIP:			18015

    ISSUER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ORASURE TECHNOLOGIES INC
    		CENTRAL INDEX KEY:			0001116463
    		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
    		IRS NUMBER:				364370966
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	BUSINESS ADDRESS:
    		STREET 1:		220 E FIRST ST
    		CITY:			BETHLEHEM
    		STATE:			PA
    		ZIP:			18015
    		BUSINESS PHONE:		5036416115

    	MAIL ADDRESS:
    		STREET 1:		220 E FIRST ST
    		CITY:			BETHLEHEM
    		STATE:			PA
    		ZIP:			18015
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>4
    <SEQUENCE>1
    <FILENAME>form4.xml
    <DESCRIPTION>STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
    <TEXT>
    Document 1 - file: form4.html

    Document 1 - RAW XML: form4.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-24.1
    <SEQUENCE>2
    <FILENAME>exhibit24-1.htm
    <DESCRIPTION>POA
    <TEXT>
    Document 2 - file: exhibit24-1.htm

    </DOCUMENT>
    </SEC-DOCUMENT>