<SEC-DOCUMENT>0001104659-26-083906-index.html : 20260715
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<ACCEPTANCE-DATETIME>20260715163019
ACCESSION NUMBER:		0001104659-26-083906
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20260715
DATE AS OF CHANGE:		20260715

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ProQR Therapeutics N.V.
		CENTRAL INDEX KEY:			0001612940
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			P7
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-297272
		FILM NUMBER:		261177686

	BUSINESS ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		ZERNIKEDREEF 9
		CITY:			LEIDEN
		PROVINCE COUNTRY:   	P7
		BUSINESS PHONE:		31 88 166 7000

	MAIL ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		ZERNIKEDREEF 9
		CITY:			LEIDEN
		PROVINCE COUNTRY:   	P7

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ProQR Therapeutics B.V.
		DATE OF NAME CHANGE:	20140708
</SEC-HEADER>
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<TEXT>
Document 1 - file: tm2619566-4_424b5.htm

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Document 2 - file: lg_proqrreg-4c.jpg

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<SEQUENCE>3
<FILENAME>fc_pipeline-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: fc_pipeline-4clr.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>fc_natural-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: fc_natural-4clr.jpg

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