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Securities Purchase Agreement - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Mar. 26, 2015 | Sep. 08, 2014 | Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014 | Nov. 17, 2014 | Nov. 16, 2014
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Common stock par value per share |  |  | $ 0.001 | $ 0.001 |  |  |
Aggregate gross proceeds from the issuance of Series C preferred stock and common stock |  |  | $ 0 | $ 0 | $ 14,163 |  |
Change in fair value of warrant liability |  |  | 0 | 0 | 3,280 |  |
Proceeds from the exercise of warrants |  |  | $ 0 | $ 8,644 | $ 0 |  |
Common stock shares reserved for issuance |  |  | 46,512,010 | 44,841,572 |  |  |
Common stock, shares authorized |  |  | 150,000,000 | 150,000,000 |  | 100,000,000 | 50,000,000
Series C Preferred Stock |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Number of shares sold |  | 87,196 |  |  |  |  |
Convertible preferred stock par value per share |  | $ 0.001 |  |  |  |  |
Price per share |  | $ 17.50 |  |  |  |  |
Aggregate gross proceeds from the issuance of Series C preferred stock and common stock |  | $ 14,400 |  |  |  |  |
Series C Preferred Stock, shares issued upon conversion into common stock |  |  |  |  |  | 10 |
Beneficial conversion feature |  | $ 400 |  |  |  |  |
Series C Convertible Preferred Stock |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Common stock shares reserved for issuance |  | 871,960 |  |  |  |  |
Common Stock |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Number of shares sold |  | 7,363,334 |  | 2,158,000 | 7,363,000 |  |
Common stock par value per share |  | $ 0.001 |  |  |  |  |
Price per share |  | $ 1.75 |  |  |  |  |
Common stock warrants outstanding |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Warrants to purchase common stock sold (shares) |  | 4,117,647 |  |  |  |  |
Exercise price per share |  | $ 2.26 |  |  |  |  |
2014 Warrant |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Proceeds from the exercise of warrants | $ 8,600 |  |  |  |  |  |
2014 Warrant | Common stock warrants outstanding |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Number of shares sold | 3,824,600 |  |  |  |  |  |
Exercise price per share |  | $ 2.26 |  |  |  |  |
2015 Warrant |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Change in fair value of warrant liability |  |  |  | $ 3,500 |  |  |
2015 Warrant | Common stock warrants outstanding |  |  |  |  |  |  |
Changes In Equity And Comprehensive Income Line Items [Line Items] |  |  |  |  |  |  |
Warrants to purchase common stock sold (shares) | 1,593,583 |  |  |  |  |  |
Exercise price per share | $ 5.50 |  |  |  |  |  |

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