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Share-based Compensation - Summary of Stock Option Activity (Detail) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Stock Options Outstanding    
Outstanding — beginning of period 6,084,836 3,064,880
Granted 1,051,550 6,656,737
Exercised (78,384) (273,005)
Canceled (701,799) (3,363,776)
Outstanding — end of period 6,356,203 6,084,836
Vested and Expected to Vest — December 31, 2016 5,729,553  
Exercisable — December 31, 2016 2,461,614  
Weighted-Average Exercise Price Per Option    
Outstanding — beginning of period $ 3.01 $ 5.27
Granted 1.65 3.02
Exercised 1.12 2.26
Canceled 4.35 5.14
Outstanding — end of period 2.64 $ 3.01
Vested and Expected to Vest — December 31, 2016 2.72  
Exercisable — December 31, 2016 $ 3.69  
Weighted-Average Remaining Contractual Term (Years), Options Outstanding 7 years 11 months 10 days  
Weighted-Average Remaining Contractual Term (Years), Options Vested and Expected to Vest 7 years 10 months 1 day  
Weighted-Average Remaining Contractual Term (Years), Options Exercisable 6 years 6 months 29 days  
Aggregate Intrinsic Value, Options Outstanding $ 3,592  
Aggregate Intrinsic Value, Options Vested and Expected to Vest 3,180  
Aggregate Intrinsic Value, Options Exercisable $ 1,023