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Securities Purchase Agreement - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Mar. 26, 2015
Sep. 08, 2014
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Nov. 17, 2014
Nov. 16, 2014
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Common stock par value per share     $ 0.001 $ 0.001      
Aggregate gross proceeds from the issuance of Series C preferred stock and common stock     $ 0 $ 0 $ 14,163    
Change in fair value of warrant liability     0 0 3,280    
Proceeds from the exercise of warrants     $ 0 $ 8,644 $ 0    
Common stock shares reserved for issuance     46,512,010 44,841,572      
Common stock, shares authorized     150,000,000 150,000,000   100,000,000 50,000,000
Series C Preferred Stock              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Number of shares sold   87,196          
Convertible preferred stock par value per share   $ 0.001          
Price per share   $ 17.50          
Aggregate gross proceeds from the issuance of Series C preferred stock and common stock   $ 14,400          
Series C Preferred Stock, shares issued upon conversion into common stock           10  
Beneficial conversion feature   $ 400          
Series C Convertible Preferred Stock              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Common stock shares reserved for issuance   871,960          
Common Stock              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Number of shares sold   7,363,334   2,158,000 7,363,000    
Common stock par value per share   $ 0.001          
Price per share   $ 1.75          
Common stock warrants outstanding              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Warrants to purchase common stock sold (shares)   4,117,647          
Exercise price per share   $ 2.26          
2014 Warrant              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Proceeds from the exercise of warrants $ 8,600            
2014 Warrant | Common stock warrants outstanding              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Number of shares sold 3,824,600            
Exercise price per share   $ 2.26          
2015 Warrant              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Change in fair value of warrant liability       $ 3,500      
2015 Warrant | Common stock warrants outstanding              
Changes In Equity And Comprehensive Income Line Items [Line Items]              
Warrants to purchase common stock sold (shares) 1,593,583            
Exercise price per share $ 5.50