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Income Taxes - Additional Information (Detail) - USD ($) | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017
Operating Loss Carryforwards [Line Items] |  |
Valuation allowances recognized in the current year | $ 2,900,000 | $ 16,400,000
Effect of tax act on valuation allowance |  | (38,800,000)
Effect of tax act on deferred tax assets |  | (38,800,000)
Effect of Tax Act | $ 0 | $ (971,000)
Statutory federal income tax rate | 21.00% | 34.00%
Internal Revenue Code related to annual use of operating loss carry forwards | annual use of the Company’s net operating loss and research and development credit carryforwards may be limited in the event a cumulative change in ownership of more than 50% occurs within a rolling three-year period |
Internal Revenue Code ownership percentage change | 50.00% |
Income tax benefit recognized related to uncertain tax positions | $ 0 | $ 0
Interest expense related to uncertain tax positions | 0 | 0
Liability related to unrecognized tax benefits | 0 | $ 0
Domestic Tax Authority |  |
Operating Loss Carryforwards [Line Items] |  |
Net operating loss carryforwards | $ 350,300,000 |
Net operating loss expiration beginning date | 2021 |
Research and development tax credit carryforwards | $ 9,400,000 |
Tax credits expiration beginning date | 2026 |
California Franchise Tax Board |  |
Operating Loss Carryforwards [Line Items] |  |
Net operating loss carryforwards | $ 38,900,000 |
Net operating loss expiration beginning date | 2028 |
Research and development tax credit carryforwards | $ 10,900,000 |
Foreign Tax Authority |  |
Operating Loss Carryforwards [Line Items] |  |
Net operating loss carryforwards | $ 53,100,000 |

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