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Income Taxes - Provision for Income Taxes Reconciliation to Statutory Federal Income Tax Rate (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Income Tax Disclosure [Abstract]      
Federal tax benefit, at statutory rate $ (10,021) $ (23,192) $ (8,311)
State benefit, net of federal benefit (148) (1,285) 27
Foreign tax rate difference (358) (140) 476
Valuation allowance against future tax benefits 6,029 26,410 9,168
Gain on sale of foreign subsidiaries 3,008 0 0
Sub-part F income 791 0 0
Loss on conversion of debt 0 2,015 0
Research and development credits (1,415) (2,355) (1,456)
Share-based compensation (879) (1,134) 341
Non-deductible officers compensation 1,449 0 0
True-up of prior year provisions 1,681 0 0
Other 54 429 291
Provision for income taxes $ 191 $ 748 $ 536