<SEC-DOCUMENT>0001567619-22-018271.txt : 20221005
<SEC-HEADER>0001567619-22-018271.hdr.sgml : 20221005
<ACCEPTANCE-DATETIME>20221005161655
ACCESSION NUMBER:		0001567619-22-018271
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20221003
FILED AS OF DATE:		20221005
DATE AS OF CHANGE:		20221005

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Norrett Kevin
		CENTRAL INDEX KEY:			0001819690

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34705
		FILM NUMBER:		221295792

	MAIL ADDRESS:	
		STREET 1:		C/O SIERRA ONCOLOGY, INC.
		STREET 2:		1820 GATEWAY DRIVE, SUITE 110
		CITY:			SAN MATEO
		STATE:			CA
		ZIP:			94404

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CODEXIS, INC.
		CENTRAL INDEX KEY:			0001200375
		STANDARD INDUSTRIAL CLASSIFICATION:	INDUSTRIAL ORGANIC CHEMICALS [2860]
		IRS NUMBER:				710872999
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		200 PENOBSCOT DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063
		BUSINESS PHONE:		650-421-8100

	MAIL ADDRESS:	
		STREET 1:		200 PENOBSCOT DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CODEXIS INC
		DATE OF NAME CHANGE:	20021022
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc1.xml
<DESCRIPTION>FORM 3
<TEXT>
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<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2022-10-03</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001200375</issuerCik>
        <issuerName>CODEXIS, INC.</issuerName>
        <issuerTradingSymbol>CDXS</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001819690</rptOwnerCik>
            <rptOwnerName>Norrett Kevin</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CODEXIS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>200 PENOBSCOT DRIVE</rptOwnerStreet2>
            <rptOwnerCity>REDWOOD CITY</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94063</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Operating Officer</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <ownerSignature>
        <signatureName>/s/ Ross Taylor, as Attorney-in-Fact for Kevin Norrett</signatureName>
        <signatureDate>2022-10-05</signatureDate>
    </ownerSignature>
</ownershipDocument>
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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>poa_norrett.htm
<TEXT>
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    <div style="text-align: center; margin-bottom: 12pt; font-size: 12pt; font-weight: bold;">POWER OF ATTORNEY</div>
    <div style="text-indent: 36pt; color: #000000;">Know all by these presents, that the undersigned hereby constitutes and appoints each of (i) the President of Codexis,
      Inc., a Delaware corporation (the &#8220;<font style="font-weight: bold;">Company</font>&#8221;), who is currently Stephen Dilly, (ii) the Company's Chief Financial Officer, who is currently Dean
      Ross Taylor, Jr., (iii) the Company&#8217;s General Counsel, and (iv) the Company&#8217;s Senior Corporate Counsel, who is currently Richard A. Sabalot, and their respective successors, signing singly, with full power of substitution, as the undersigned's true
      and lawful attorney-in-fact to:</div>
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          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">(1)</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: #000000;">execute for and on behalf of the undersigned, in the undersigned&#8217;s capacity as a director and/or officer of the Company, Forms&#160;3, 4 and 5 (including
              amendments thereto) in accordance with Section&#160;16(a) of the Securities Exchange Act of 1934 and the rules and regulations thereunder and a Form ID, Uniform Application for Access Codes to File on EDGAR;</div>
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    <table cellspacing="0" cellpadding="0" id="ze088fc8e56a7423484cd81f33a9c9985" class="DSPFListTable" style="font-family: 'Times New Roman', Times, serif; font-size: 10pt; width: 100%; text-align: left; color: #000000; margin-top: 12pt;">

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          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">(2)</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: #000000;">do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Forms 3, 4 or
              5 or Form ID and timely file such forms (including amendments thereto) and application with the United States Securities and Exchange Commission and any stock exchange or similar authority; and</div>
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          <td style="width: 36pt; vertical-align: top; color: rgb(0, 0, 0); font-family: 'Times New Roman',Times,serif;">(3)</td>
          <td style="width: auto; vertical-align: top;">
            <div style="color: #000000;">take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in
              the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain
              such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact's discretion.</div>
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    </table>
    <div><br>
    </div>
    <div style="text-indent: 36pt; color: #000000;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act
      and thing whatsoever requisite, necessary or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of
      substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers
      herein granted.&#160; The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities to comply with
      Section&#160;16 of the Securities Exchange Act of 1934.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">The undersigned agrees that each such attorney-in-fact herein may rely entirely on information furnished orally or in writing by the
      undersigned to such attorney-in-fact.&#160; The undersigned also agrees to indemnify and hold harmless the Company and each such attorney-in-fact against any losses, claims, damages or liabilities (or actions in these respects) that arise out of or are
      based upon any untrue statements or omission of necessary facts in the information provided by the undersigned to such attorney-in fact for purposes of executing, acknowledging, delivering or filing Forms 3, 4 or 5 (including amendments thereto) or
      Form ID and agrees to reimburse the Company and such attorney-in-fact for any legal or other expenses reasonably incurred in connection with investigating or defending against any such loss, claim, damage, liability or action.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt; color: #000000;">This Power of Attorney supersedes any power of attorney previously executed by the undersigned regarding the purposes
      outlined in the first paragraph hereof (&#8220;<font style="font-weight: bold; font-style: italic;">Prior Powers of Attorney</font>&#8221;), and the authority of the attorneys-in-fact named in any
      Prior Powers of Attorney is hereby revoked.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms&#160;3, 4 or 5 with
      respect to the undersigned's holdings of and transactions in securities issued by the Company, unless earlier (a)&#160;revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact or (b)&#160;superseded by a new power of attorney
      regarding the purposes outlined in the first paragraph hereof dated as of a later date.</div>
    <div><br>
    </div>
    <div style="text-indent: 36pt; color: #000000;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 29<sup style="vertical-align: text-top; line-height: 1; font-size: smaller;">th</sup> day of
      September, 2022.</div>
    <div><br>
    </div>
    <div style="margin-left: 279pt; margin-top: 12pt;"><u>/s/ Kevin Norrett</u><font class="TRGRRTFtoHTMLTab" style="display: inline-block; text-indent: 0px; font-size: 1px; width: 117pt">&#160;</font><font style="font-size: 1px;"><font class="TRGRRTFtoHTMLTab" style="display: inline-block; text-indent: 0px; width: 12pt;">&#160;</font></font></div>
    <div style="margin-left: 279pt; font-weight: bold;">Kevin Norrett</div>
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