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Revenue Recognition (Tables) | 3 Months Ended
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Mar. 31, 2023
Revenue from Contract with Customer [Abstract] |
Disaggregation of revenue | Segment information is as follows (in thousands):
| Three Months Ended March 31, 2023 |  | Three Months Ended March 31, 2022
| Performance Enzymes |  | Novel Biotherapeutics |  | Total |  | Performance Enzymes |  | Novel Biotherapeutics |  | Total
Major products and service: |  |  |  |  |  |  |  |  |  |  |
Product revenue | $ | 8,364 |  |  | $ | — |  |  | $ | 8,364 |  |  | $ | 30,690 |  |  | $ | — |  |  | $ | 30,690 |
Research and development revenue | 1,122 |  |  | 3,496 |  |  | 4,618 |  |  | 2,409 |  |  | 2,241 |  |  | 4,650 |
Total revenues | $ | 9,486 |  |  | $ | 3,496 |  |  | $ | 12,982 |  |  | $ | 33,099 |  |  | $ | 2,241 |  |  | $ | 35,340 |
Primary geographical markets: |  |  |  |  |  |  |  |  |  |  |
Americas | $ | 918 |  |  | $ | 1,666 |  |  | $ | 2,584 |  |  | $ | 2,553 |  |  | $ | 1,179 |  |  | $ | 3,732 |
EMEA | 1,259 |  |  | 1,830 |  |  | 3,089 |  |  | 3,065 |  |  | 1,062 |  |  | 4,127 |
APAC | 7,309 |  |  | — |  |  | 7,309 |  |  | 27,481 |  |  | — |  |  | 27,481 |
Total revenues | $ | 9,486 |  |  | $ | 3,496 |  |  | $ | 12,982 |  |  | $ | 33,099 |  |  | $ | 2,241 |  |  | $ | 35,340 |
Contract with customer | The following table presents balances of contract assets, unbilled receivables, contract costs, and contract liabilities (in thousands):
| March 31, 2023 |  | December 31, 2022
Contract assets | $ | 2,449 |  |  | $ | 2,116 |
Unbilled receivables | $ | 7,797 |  |  | $ | 7,016 |
Contract costs | $ | 2 |  |  | $ | 19 |
Contract liabilities: deferred revenue | $ | 28,882 |  |  | $ | 30,609 |
We recognized t he following revenues (in thousands):
| Three Months Ended March 31,
Revenue recognized in the period for: | 2023 |  | 2022
Amounts included in contract liabilities at the beginning of the period: |  |  |
Performance obligations satisfied | $ | 1,602 |  |  | $ | 1,094 |
Changes in the period: |  |  |
Changes in the estimated transaction price allocated to performance obligations satisfied in prior periods | (216) |  |  | 215 |
Performance obligations satisfied from new activities in the period - contract revenue | 11,596 |  |  | 34,031 |
Total revenues | $ | 12,982 |  |  | $ | 35,340 |
Performance obligation, expected timing of satisfaction | The following table includes estimated revenue expected to be recognized in the future related to performance obligations that are unsatisfied or partially unsatisfied at the end of the reporting periods. The estimated revenue does not include contracts with original durations of one year or less, amounts of variable consideration attributable to royalties, or contract renewals that are unexercised as of March 31, 2023. Th e balances in the table below are partially based on judgments involved in estimating future orders from customers subject to the exercise of material rights pursuant to respective contracts as of March 31, 2023 (in thousands):
| Remainder of 2023 |  | 2024 |  | 2025 |  | 2026 and Thereafter |  |  |  | Total
Product revenue | $ | 5,891 |  |  | $ | 12,050 |  |  | $ | 100 |  |  | $ | 3,339 |  |  |  |  | $ | 21,380 |
Research and development revenue | 7,480 |  |  | 22 |  |  | — |  |  | — |  |  |  |  | 7,502 |
Total revenues | $ | 13,371 |  |  | $ | 12,072 |  |  | $ | 100 |  |  | $ | 3,339 |  |  |  |  | $ | 28,882 |

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- Definition Tabular disclosure of receivable, contract asset, and contract liability from contract with customer. Includes, but is not limited to, change in contract asset and contract liability. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 10 -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL49130551-203045 + Details
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- Definition Tabular disclosure of disaggregation of revenue into categories depicting how nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factor. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 5 -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL49130545-203045 + Details
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- Definition Tabular disclosure of expected timing for satisfying remaining performance obligation. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 13 -Subparagraph (b)(1) -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL49130556-203045 + Details
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