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Balance Sheets Details - Property and Equipment, net (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Property, Plant and Equipment [Line Items]      
Property and equipment $ 64,771   $ 62,435
Less: accumulated depreciation and amortization (41,162)   (39,821)
Property and equipment, net 23,609   22,614
Depreciation expense 1,466 $ 1,215  
Laboratory equipment      
Property, Plant and Equipment [Line Items]      
Property and equipment 40,489   39,679
Leasehold improvements      
Property, Plant and Equipment [Line Items]      
Property and equipment 16,694   16,633
Computer equipment and software      
Property, Plant and Equipment [Line Items]      
Property and equipment 3,039   3,039
Office equipment and furniture      
Property, Plant and Equipment [Line Items]      
Property and equipment 1,360   1,345
Construction in progress      
Property, Plant and Equipment [Line Items]      
Property and equipment $ 3,189   $ 1,739