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Condensed Consolidated Statements of Cash Flows
$ in Thousands
 3 Months Ended
Mar. 31, 2023
USD ($)
Mar. 31, 2022
USD ($)
Operating activities:    
Net loss $ (22,617) $ (8,356)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 1,466 1,215
Amortization expense - right-of-use assets - operating and finance leases 1,249 1,200
Stock-based compensation 2,809 3,838
Equity securities earned from research and development activities ($0 and ($245) from a related party) (50) (245)
Other non-cash items (5) (7)
Changes in operating assets and liabilities:    
Financial assets 20,856 (6,463)
Inventories 33 (400)
Prepaid expenses and other assets 586 1,397
Accounts payable 694 (1,029)
Accrued compensation and other accrued liabilities (11,091) (121)
Other long-term liabilities (1,415) (1,192)
Deferred revenue (1,727) (1,023)
Net cash used in operating activities (9,212) (11,186)
Investing activities:    
Purchase of property and equipment (2,539) (5,089)
Proceeds from sale of property and equipment 5 7
Investment in non-marketable securities (750) (5,000)
Net cash used in investing activities (3,284) (10,082)
Financing activities:    
Proceeds from exercises of stock options 281 181
Proceeds from issuance of common stock in connection with public offering 1,540 0
Costs incurred in connection with issuance of common stock at public offering (65) (42)
Taxes paid related to net share settlement of equity awards (404) (1,419)
Net cash provided by (used in) financing activities 1,352 (1,280)
Net decrease in cash, cash equivalents and restricted cash (11,144) (22,548)
Cash, cash equivalents and restricted cash at the beginning of the period 116,026 118,895
Cash, cash equivalents and restricted cash at the end of the period 104,882 96,347
Supplemental disclosure of cash flow information:    
Interest paid 7 5
Income taxes paid 193 0
Supplemental non-cash investing and financing activities:    
Capital expenditures incurred but not yet paid 819 789
Cash reconciliation:    
Cash and cash equivalents 102,831 94,260
Restricted cash, current and non-current 2,051 2,087
Total cash, cash equivalents and restricted cash $ 104,882 $ 96,347