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Pay vs Performance Disclosure - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Pay vs Performance Disclosure [Table]      
Pay vs Performance [Table Text Block]
Pay-Versus-Performance
Disclosure
As required by Item 402(v) of Regulation
S-K,
we are providing the following information about the relationship between the compensation actually paid to our named executive officers and certain aspects of our financial performance. For further information concerning our pay for performance philosophy and how executive compensation aligns with our performance, please refer to “
Executive Compensation – Compensation Discussion and Analysis
.”
Pay-Versus-Performance
Table
 
   
Pay Versus Performance
 
                           
Average

Summary

Compensation

Table Total

for

Non-PEO

NEOs

(d)
   
Average

Compensation

Actually

Paid

for

Non-PEO

NEOs

(e)
   
Value of

Initial Fixed $100

Investment

Based On:
             
Year
(a)
 
Summary

Compensation

Table Total

for

PEO

(Current)

(b)
   
Compensation

Actually

Paid

for

PEO

(Current)

(c)
   
Summary

Compensation

Table Total

for

PEO

(Former)

(b)
   
Compensation

Actually

Paid

for

PEO

(Former)

(c)
   
Total
Shareholder
Return

(f)
   
Peer
Group
Total
Return
(g)
   
Net

Income

(h)
   
Company-

Selected

Measure:

Revenue

(i)
 
2022
  $ 5,876,384     $ 3,461,766     $ 3,419,955     ($ 3,857,296   $ 1,919,623     $ 846,088     $ 29     $ 114     ($ 33,592,000   $ 138,590,000  
2021
    N/A       N/A     $ 3,438,179     $ 6,518,158     $ 1,264,192     $ 2,093,766     $ 196     $ 126     ($ 21,279,000   $ 104,754,000  
2020
    N/A       N/A     $ 2,960,857     $ 3,592,089     $ 833,528     $ 1,569,978     $ 137     $ 126     ($ 24,010,000   $ 69,056,000  
 
(1)
 
During fiscal years 2020, 2021 and 2022, our PEOs and
non-PEO
NEOs were as follows:.
 
Year
   PEO (Current
CEO)
(1)
   PEO (Former
CEO)
(2)
  
Non-PEO NEOs
2022    Stephen Dilly    John Nicols    Ross Taylor, Kevin Norrett, Margaret
Fitzgerald
2021         John Nicols    Ross Taylor
2020         John Nicols    Ross Taylor
 
(2)
 
The dollar amounts reported in column (c) and (e) represent the amount of “compensation actually paid” to our
PEOs
and
Non-PEO
NEOs in each respective year. The dollar amounts do not reflect the actual amount of compensation earned or received during the applicable fiscal year. There are no material differences between the assumptions used to compute the valuation of the equity awards for calculating the compensation actually paid from the assumptions used to compute the valuation of such equity awards as of the grant date. In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to the total compensation of our PEOs and
non-PEO
NEOs for each year to determine the “compensation actually paid” to him or her:
 
   
PEO (Current)
 
               
2020
    
2021
    
2022
 
    Summary Compensation Table - Total Compensation      (a)        N/A        N/A      $ 5,876,384  
-
  Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year      (b)        N/A        N/A      $ 5,139,542  
+
  Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year      (c)        N/A        N/A      $ 3,127,949  
+
  Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years      (d)        N/A        N/A        ($158,808)  
+
  Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year      (e)        N/A        N/A      $ —    
+
  Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year      (f)        N/A        N/A        ($244,217)  
-
  Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year      (g)        N/A        N/A      $ —    
=
  Compensation Actually Paid                               $ 3,461,766  
 
   
PEO (Former)
 
               
2020
    
2021
    
2022
 
    Summary Compensation Table - Total Compensation      (a)      $ 2,960,857      $ 3,438,179      $ 3,419,955  
-
  Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year      (b)      $ 1,795,800      $ 2,109,577      $ 2,521,160  
+
  Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year      (c)      $ 2,968,985      $ 3,900,233      $ —    
+
  Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years      (d)      $ 559,924      $ 1,262,770      $ —    
+
  Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year      (e)      $ —        $ —        $ —    
+
  Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year      (f)      ($ 1,101,877)      $ 26,552      ($ 2,208,709)  
-
  Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year      (g)      $ —        $ —        $ 2,547,383  
=
  Compensation Actually Paid             $ 3,592,089      $ 6,518,158      ($ 3,857,296)  
 
   
NEO Average
 
            
2020
   
2021
   
2022
 
    Summary Compensation Table - Total Compensation    (a)   $ 833,528     $ 1,264,192     $ 1,919,623  
-
  Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year    (b)   $ 228,565     $ 596,882     $ 1,590,832  
+
  Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year    (c)   $ 872,284     $ 951,834     $ 978,796  
+
  Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years    (d)   $ 118,975     $ 426,740       ($250,128)  
+
  Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year    (e)   $ —       $ —       $ —    
+
  Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year    (f)     ($26,244)     $ 47,882       ($211,371)  
-
  Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year    (g)   $ —       $ —       $ —    
=
  Compensation Actually Paid        $ 1,569,978     $ 2,093,766     $ 846,088  
 
(3)
Cumulative TSR is calculated by dividing the sum of the cumulative amount of dividends during the measurement period, assuming dividend reinvestment, and the difference between our share price at the end of the applicable measurement period and the beginning assuming $100 of investment as of December 31, 2019.
(4)
The peer group used for this purpose is the NASDAQ Biotechnology Index.
   
Company Selected Measure Name Revenue    
Named Executive Officers, Footnote [Text Block]
 
Year
   PEO (Current
CEO)
(1)
   PEO (Former
CEO)
(2)
  
Non-PEO NEOs
2022    Stephen Dilly    John Nicols    Ross Taylor, Kevin Norrett, Margaret
Fitzgerald
2021         John Nicols    Ross Taylor
2020         John Nicols    Ross Taylor
 
   
Peer Group Issuers, Footnote [Text Block]
(4)
The peer group used for this purpose is the NASDAQ Biotechnology Index.
   
Adjustment To PEO Compensation, Footnote [Text Block]
(2)
 
The dollar amounts reported in column (c) and (e) represent the amount of “compensation actually paid” to our
PEOs
and
Non-PEO
NEOs in each respective year. The dollar amounts do not reflect the actual amount of compensation earned or received during the applicable fiscal year. There are no material differences between the assumptions used to compute the valuation of the equity awards for calculating the compensation actually paid from the assumptions used to compute the valuation of such equity awards as of the grant date. In accordance with the requirements of Item 402(v) of Regulation
S-K,
the following adjustments were made to the total compensation of our PEOs and
non-PEO
NEOs for each year to determine the “compensation actually paid” to him or her:
 
   
PEO (Current)
 
               
2020
    
2021
    
2022
 
    Summary Compensation Table - Total Compensation      (a)        N/A        N/A      $ 5,876,384  
-
  Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year      (b)        N/A        N/A      $ 5,139,542  
+
  Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year      (c)        N/A        N/A      $ 3,127,949  
+
  Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years      (d)        N/A        N/A        ($158,808)  
+
  Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year      (e)        N/A        N/A      $ —    
+
  Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year      (f)        N/A        N/A        ($244,217)  
-
  Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year      (g)        N/A        N/A      $ —    
=
  Compensation Actually Paid                               $ 3,461,766  
 
   
PEO (Former)
 
               
2020
    
2021
    
2022
 
    Summary Compensation Table - Total Compensation      (a)      $ 2,960,857      $ 3,438,179      $ 3,419,955  
-
  Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year      (b)      $ 1,795,800      $ 2,109,577      $ 2,521,160  
+
  Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year      (c)      $ 2,968,985      $ 3,900,233      $ —    
+
  Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years      (d)      $ 559,924      $ 1,262,770      $ —    
+
  Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year      (e)      $ —        $ —        $ —    
+
  Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year      (f)      ($ 1,101,877)      $ 26,552      ($ 2,208,709)  
-
  Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year      (g)      $ —        $ —        $ 2,547,383  
=
  Compensation Actually Paid             $ 3,592,089      $ 6,518,158      ($ 3,857,296)  
   
Non-PEO NEO Average Total Compensation Amount $ 1,919,623 $ 1,264,192 $ 833,528
Non-PEO NEO Average Compensation Actually Paid Amount $ 846,088 2,093,766 1,569,978
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]  
   
NEO Average
 
            
2020
   
2021
   
2022
 
    Summary Compensation Table - Total Compensation    (a)   $ 833,528     $ 1,264,192     $ 1,919,623  
-
  Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year    (b)   $ 228,565     $ 596,882     $ 1,590,832  
+
  Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year    (c)   $ 872,284     $ 951,834     $ 978,796  
+
  Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years    (d)   $ 118,975     $ 426,740       ($250,128)  
+
  Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year    (e)   $ —       $ —       $ —    
+
  Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year    (f)     ($26,244)     $ 47,882       ($211,371)  
-
  Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year    (g)   $ —       $ —       $ —    
=
  Compensation Actually Paid        $ 1,569,978     $ 2,093,766     $ 846,088  
   
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
The following graph illustrates the relationship between compensation actually paid to our PEOs and our
non-PEO
NEOs and our TSR for the period presented in the
Pay-Versus-Performance
table.
 
 
LOGO
 
   
Compensation Actually Paid vs. Net Income [Text Block]
The following graph illustrates the relationship between compensation actually paid to our PEOs and our
non-PEO
NEOs and our net income for the period presented in the
Pay-Versus-Performance
table.
 
LOGO
 
   
Compensation Actually Paid vs. Company Selected Measure [Text Block]
The following graph illustrates the relationship between compensation actually paid to our PEOs and our
non-PEO
NEOs and o
ur revenue for the period presented in the
Pay-Versus-Performance
table.
 
LOGO
 
   
Total Shareholder Return Vs Peer Group [Text Block]
The following graph illustrates the relationship between compensation actually paid to our PEOs and our
non-PEO
NEOs and our TSR for the period presented in the
Pay-Versus-Performance
table.
 
 
LOGO
 
   
Tabular List [Table Text Block] The following table sets forth the company’s most important financial performance measures used to link NEO compensation actually paid during 2022 to company performance.
 
   
Company Performance Metrics
   
   
Total Revenue
   
   
Product Revenue
   
   
Product Gross Margin
   
   
Cash Reserves
   
   
Total Shareholder Return Amount $ 29 196 137
Peer Group Total Shareholder Return Amount 114 126 126
Net Income (Loss) $ (33,592,000) $ (21,279,000) $ (24,010,000)
Company Selected Measure Amount 138,590,000 104,754,000 69,056,000
Measure [Axis]: 1      
Pay vs Performance Disclosure [Table]      
Measure Name Total Revenue    
Measure [Axis]: 2      
Pay vs Performance Disclosure [Table]      
Measure Name Product Revenue    
Measure [Axis]: 3      
Pay vs Performance Disclosure [Table]      
Measure Name Product Gross Margin    
Measure [Axis]: 4      
Pay vs Performance Disclosure [Table]      
Measure Name Cash Reserves    
Stephen Dilly [Member]      
Pay vs Performance Disclosure [Table]      
PEO Total Compensation Amount $ 5,876,384    
PEO Actually Paid Compensation Amount $ 3,461,766    
PEO Name Stephen Dilly    
John Nicols [Member]      
Pay vs Performance Disclosure [Table]      
PEO Total Compensation Amount $ 3,419,955 $ 3,438,179 $ 2,960,857
PEO Actually Paid Compensation Amount $ (3,857,296) 6,518,158 3,592,089
PEO Name John Nicols    
PEO [Member] | Stephen Dilly [Member] | Fair Value of Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount $ 5,139,542    
PEO [Member] | Stephen Dilly [Member] | Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 3,127,949    
PEO [Member] | Stephen Dilly [Member] | Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (158,808)    
PEO [Member] | Stephen Dilly [Member] | Fair Value at Vesting of Stock Awards and Option Awards Granted Vested [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0    
PEO [Member] | Stephen Dilly [Member] | Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted Which Applicable Vesting Conditions [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (244,217)    
PEO [Member] | Stephen Dilly [Member] | Fair Value Year End of Stock Awards and Option Awards Granted That Failed to Meet Applicable Vesting Conditions [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0    
PEO [Member] | John Nicols [Member] | Fair Value of Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 2,521,160 2,109,577 1,795,800
PEO [Member] | John Nicols [Member] | Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0 3,900,233 2,968,985
PEO [Member] | John Nicols [Member] | Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0 1,262,770 559,924
PEO [Member] | John Nicols [Member] | Fair Value at Vesting of Stock Awards and Option Awards Granted Vested [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0 0 0
PEO [Member] | John Nicols [Member] | Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted Which Applicable Vesting Conditions [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (2,208,709) 26,552 (1,101,877)
PEO [Member] | John Nicols [Member] | Fair Value Year End of Stock Awards and Option Awards Granted That Failed to Meet Applicable Vesting Conditions [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 2,547,383 0 0
Non-PEO NEO [Member] | Fair Value of Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 1,590,832 596,882 228,565
Non-PEO NEO [Member] | Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 978,796 951,834 872,284
Non-PEO NEO [Member] | Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (250,128) 426,740 118,975
Non-PEO NEO [Member] | Fair Value at Vesting of Stock Awards and Option Awards Granted Vested [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount 0 0 0
Non-PEO NEO [Member] | Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted Which Applicable Vesting Conditions [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount (211,371) 47,882 (26,244)
Non-PEO NEO [Member] | Fair Value Year End of Stock Awards and Option Awards Granted That Failed to Meet Applicable Vesting Conditions [Member]      
Pay vs Performance Disclosure [Table]      
Adjustment to Compensation Amount $ 0 $ 0 $ 0