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Investments in Non-Marketable Securities - Narrative (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Mar. 31, 2023 | Jul. 31, 2022 | Dec. 31, 2021 | Sep. 30, 2021 | Jul. 31, 2021 | Dec. 31, 2023 | Sep. 30, 2023 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Nov. 30, 2023 | Sep. 30, 2022 | Mar. 31, 2022 | Nov. 30, 2020
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Available-for-sale non-marketable interest-bearing debt securities |  |  |  |  |  | $ 0 |  | $ 0 | $ 0 |  |  |  |  | $ 1,000
Non-marketable debt security at carrying value |  |  |  |  | $ 1,300 |  |  |  |  |  |  |  |  |
Interest income from amortization of discount |  |  |  |  |  |  |  |  |  | $ 300 |  |  |  |
Investments in non-marketable securities |  |  |  |  |  |  |  | 1,191 | 5,300 | 7,630 |  |  |  |
Investment in non-marketable equity securities ($0 and $13,921 with a related party) |  |  |  |  |  | 9,700 |  | 9,700 | 20,510 |  |  |  |  |
Revenues |  |  |  |  |  |  |  | 70,143 | 138,590 | 104,754 |  |  |  |
Impairment of investment in non-marketable securities |  |  |  |  |  |  |  | 12,215 | 0 | 0 |  |  |  |
Equity securities without readily determinable fair value, upward price adjustment, annual amount |  |  |  |  |  |  |  | 200 |  |  |  |  |  |
Equity securities without readily determinable fair value, upward (downward) price adjustment, annual amount |  |  |  |  |  |  |  | 0 | 0 |  |  |  |  |
Research and development revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  | 27,237 | 21,914 | 34,097 |  |  |  |
seqWell | Research and development revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  | $ 200 |  |  |  |  |  |
Common Stock | seqWell |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock issued during period, shares, issued for services (in shares) |  |  |  |  |  |  |  | 205,279 |  |  |  |  |  |
seqWell |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity securities without readily determinable fair value (in shares) |  |  |  |  |  |  |  |  |  |  |  |  | 1,000,000 |
Investment in non-marketable equity securities ($0 and $13,921 with a related party) |  |  |  |  |  | 2,625 |  | $ 2,625 | 5,000 |  |  |  | $ 5,000 |
Impairment of investment in non-marketable securities |  |  |  |  |  |  | $ 3,000 |  |  |  |  |  |  |
Arzeda |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Investment in non-marketable equity securities ($0 and $13,921 with a related party) |  |  |  |  |  | 82 |  | 82 | 1,289 |  |  |  |  |
Impairment of investment in non-marketable securities |  |  |  |  |  | 1,200 |  |  |  |  |  |  |  |
Related Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Investments in non-marketable securities |  |  |  |  |  |  |  | 0 | 0 | 7,630 |  |  |  |
Investment in non-marketable equity securities ($0 and $13,921 with a related party) |  |  |  |  |  | $ 0 |  | 0 | 13,921 |  |  |  |  |
Related Party | Research and development revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenues |  |  |  |  |  |  |  | 0 | $ 1,245 | $ 1,955 |  |  |  |
MAI |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Impairment of investment in non-marketable securities |  |  |  |  |  |  |  | $ 8,000 |  |  |  |  |  |
Series B-2 Preferred Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-marketable debt security (in shares) |  |  |  |  | 207,070 |  |  |  |  |  |  |  |  |
Series B Preferred Stock | MAI | Related Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone payments received (in shares) |  | 1,587,049 | 1,587,049 |  |  |  |  |  |  |  |  |  |  |
Series B Preferred Stock | Arzeda |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity securities without readily determinable fair value (in shares) |  |  |  |  |  |  |  |  |  |  | 207,070 |  |  |
Series B Preferred Stock | MAI |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Investment owned, balance (in shares) | 985,545 |  |  |  |  |  |  |  |  |  |  | 9,198,423 |  |
Investments in non-marketable securities | $ 800 |  |  | $ 7,000 |  |  |  |  |  |  |  |  |  |
Common Stock | seqWell |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity securities without readily determinable fair value (in shares) |  |  |  |  |  | 205,279 |  | 205,279 |  |  |  |  |  |
Common Stock | Arzeda |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Convertible preferred stock, shares issued upon conversion (in shares) |  |  |  |  |  |  |  |  |  |  | 41,414 |  |  |
Series A and B Preferred Stock | MAI | Related Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Noncash or part noncash acquisition, noncash financial or equity instrument consideration, shares issued (in shares) |  |  |  |  |  |  |  | 19,277,914 |  |  |  |  |  |
Series C-1 Preferred Stock | seqWell |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity securities without readily determinable fair value (in shares) |  |  |  |  |  |  | 88,256 |  |  |  |  |  |  |
Common Stock Warrants | seqWell |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity securities without readily determinable fair value (in shares) |  |  |  |  |  | 44,128 | 44,128 | 44,128 |  |  |  |  |  |
Investment in non-marketable equity securities ($0 and $13,921 with a related party) |  |  |  |  |  |  | $ 400 |  |  |  |  |  |  |
Series C And C-1 Preferred Stock | seqWell |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity Securities without Readily Determinable Fair Value [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Equity securities without readily determinable fair value (in shares) |  |  |  |  |  | 1,088,256 |  | 1,088,256 |  |  |  |  |  |

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