Term of collaborative research and development agreement.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Collaborative Arrangements - Merck Sitagliptin Catalyst Supply Agreement (Details) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended		12 Months Ended
	Dec. 31, 2015	Feb. 29, 2012	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Performance obligations satisfied			$ 17,937	$ 2,038
Revenues					$ 70,143	$ 138,590	$ 104,754
Product revenue
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenues					$ 42,906	$ 116,676	$ 70,657
Sitagliptin Enzyme \| Revenue Benchmark \| Collaborative Arrangement Concentration Risk
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Concentration risk, percentage					6.00%	4.00%	9.00%
Merck \| Sitagliptin Enzyme
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenues					$ 700
Merck \| Supply Agreement
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Term of collaborative research and development agreement	5 years	5 years
Merck \| Supply Agreement \| Product revenue
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Performance obligations satisfied					$ 4,400	$ 5,900	$ 9,800