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Balance Sheets Details - Property and Equipment, net (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Dec. 31, 2023
Property, Plant and Equipment [Line Items]          
Property and equipment $ 53,787   $ 53,787   $ 54,798
Less: accumulated depreciation and amortization (39,821)   (39,821)   (39,311)
Property and equipment, net 13,966   13,966   15,487
Depreciation 1,239 $ 1,480 2,491 $ 2,946  
Research and development          
Property, Plant and Equipment [Line Items]          
Depreciation 1,020 1,242 2,052 2,486  
Selling, general and administrative          
Property, Plant and Equipment [Line Items]          
Depreciation 219 $ 238 439 $ 460  
Laboratory equipment          
Property, Plant and Equipment [Line Items]          
Property and equipment 36,547   36,547   37,216
Leasehold improvements          
Property, Plant and Equipment [Line Items]          
Property and equipment 11,960   11,960   11,912
Computer equipment and software          
Property, Plant and Equipment [Line Items]          
Property and equipment 2,651   2,651   2,565
Office equipment and furniture          
Property, Plant and Equipment [Line Items]          
Property and equipment 1,116   1,116   1,469
Construction in progress          
Property, Plant and Equipment [Line Items]          
Property and equipment $ 1,513   $ 1,513   $ 1,636