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Balance Sheets Details - Property and Equipment, net (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Dec. 31, 2023
Property, Plant and Equipment [Line Items]          
Property and equipment $ 53,989   $ 53,989   $ 54,798
Less: accumulated depreciation and amortization (40,723)   (40,723)   (39,311)
Property and equipment, net 13,266   13,266   15,487
Depreciation 1,184 $ 1,357 3,675 $ 4,302  
Research and development          
Property, Plant and Equipment [Line Items]          
Depreciation 965 1,121 3,017 3,606  
Selling, general and administrative          
Property, Plant and Equipment [Line Items]          
Depreciation 219 $ 236 658 $ 696  
Laboratory equipment          
Property, Plant and Equipment [Line Items]          
Property and equipment 36,468   36,468   37,216
Leasehold improvements          
Property, Plant and Equipment [Line Items]          
Property and equipment 12,086   12,086   11,912
Computer equipment and software          
Property, Plant and Equipment [Line Items]          
Property and equipment 2,675   2,675   2,565
Office equipment and furniture          
Property, Plant and Equipment [Line Items]          
Property and equipment 1,131   1,131   1,469
Construction in progress          
Property, Plant and Equipment [Line Items]          
Property and equipment $ 1,629   $ 1,629   $ 1,636