<SEC-DOCUMENT>0000905148-25-001031.txt : 20250401
<SEC-HEADER>0000905148-25-001031.hdr.sgml : 20250401
<ACCEPTANCE-DATETIME>20250401123924
ACCESSION NUMBER:		0000905148-25-001031
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250328
FILED AS OF DATE:		20250401
DATE AS OF CHANGE:		20250401

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Collins Cynthia
		CENTRAL INDEX KEY:			0001405692
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34705
		FILM NUMBER:		25798142

	MAIL ADDRESS:	
		STREET 1:		65 WEST WATKINS MILL ROAD
		CITY:			GAITHERSBURG
		STATE:			MD
		ZIP:			20878

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CODEXIS, INC.
		CENTRAL INDEX KEY:			0001200375
		STANDARD INDUSTRIAL CLASSIFICATION:	INDUSTRIAL ORGANIC CHEMICALS [2860]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				710872999
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		200 PENOBSCOT DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063
		BUSINESS PHONE:		650-421-8100

	MAIL ADDRESS:	
		STREET 1:		200 PENOBSCOT DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CODEXIS INC
		DATE OF NAME CHANGE:	20021022
</SEC-HEADER>
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    <periodOfReport>2025-03-28</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001200375</issuerCik>
        <issuerName>CODEXIS, INC.</issuerName>
        <issuerTradingSymbol>CDXS</issuerTradingSymbol>
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    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001405692</rptOwnerCik>
            <rptOwnerName>Collins Cynthia</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CODEXIS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>200 PENOBSCOT DRIVE</rptOwnerStreet2>
            <rptOwnerCity>REDWOOD CITY</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94063</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
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    </reportingOwner>

    <remarks>Exhibit List: Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Georgia Erbez, as Attorney-in-Fact for Cynthia Collins</signatureName>
        <signatureDate>2025-04-01</signatureDate>
    </ownerSignature>
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<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
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    <div style="text-align: center; font-weight: bold;">POWER OF ATTORNEY</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36.35pt;">Know all by these presents, that the undersigned hereby constitutes and appoints each of <a name="z_Hlk193888954"></a>(i) the Chief Financial Officer <a name="z_Hlk179200275"></a>of Codexis,
      Inc., a Delaware corporation (the &#8220;<font style="font-weight: bold;">Company</font>&#8221;), who is currently Georgia Erbez, (ii) the Company&#8217;s General Counsel or Chief Legal Officer, (iii) the Company&#8217;s Corporate Secretary and (iv) the Company&#8217;s Vice
      President of Corporate Law &amp; Privacy Officer, and their respective successors, signing singly, with full power of substitution, as the undersigned&#8217;s true and lawful attorney-in-fact to:</div>
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          <td style="width: 36pt; vertical-align: top;">(1)</td>
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            <div>execute for and on behalf of the undersigned, in the undersigned&#8217;s capacity as a director and/or officer of the Company, Forms 3, 4 and 5 (including amendments thereto) in accordance with Section 16(a) of the Securities Exchange Act of
              1934 and the rules and regulations thereunder and a Form ID, Uniform Application for Access Codes to File on EDGAR;</div>
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          <td style="width: 36pt; vertical-align: top;">(2)</td>
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            <div>enroll the undersigned in the SEC&#8217;s enhanced Electronic Data Gathering, Analysis, and Retrieval system (&#8220;EDGAR Next&#8221;), and<font style="font-weight: bold;">&#160;</font>serve as an Account Administrator for the undersigned&#8217;s account in EDGAR
              Next;</div>
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          <td style="width: 36pt; vertical-align: top;">(3)</td>
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            <div>do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Forms 3, 4 or 5 or Form ID and timely file such forms (including amendments thereto) and application
              with the United States Securities and Exchange Commission and any stock exchange or similar authority; and</div>
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    <div>&#160;</div>
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          <td style="width: 36pt; vertical-align: top;">(4)</td>
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            <div>take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the undersigned, it being understood that
              the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact&#8217;s
              discretion.</div>
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    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36.1pt;">The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary or proper to be done in the
      exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such
      attorney-in-fact, or such attorney-in-fact&#8217;s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned acknowledges that the foregoing
      attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned&#8217;s responsibilities to comply with Section 16 of the Securities Exchange Act of 1934.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36.3pt;">The undersigned agrees that each such attorney-in-fact herein may rely entirely on information furnished orally or in writing by the undersigned to such attorney-in-fact. The undersigned also
      agrees to indemnify and hold harmless the Company and each such attorney-in-fact against any losses, claims, damages or liabilities (or actions in these respects) that arise out of or are based upon any untrue statements or omission of necessary
      facts in the information provided by the undersigned to such attorney-in-fact for purposes of executing, acknowledging, delivering or filing Forms 3, 4 or 5 (including amendments thereto) or Form ID and agrees to reimburse the Company and such
      attorney-in-fact for any legal or other expenses reasonably incurred in connection with investigating or defending against any such loss, claim, damage, liability or action.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36.05pt;">This Power of Attorney supersedes any power of attorney previously executed by the undersigned regarding the purposes outlined in the first paragraph hereof (&#8220;<font style="font-weight: bold; font-style: italic;">Prior Powers of Attorney</font>&#8221;),<font style="font-weight: bold; font-style: italic;">&#160;</font>and the authority of the attorneys-in-fact named in any Prior Powers of Attorney is hereby revoked.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36.1pt;">This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms 3, 4 or 5 with respect to the undersigned&#8217;s holdings of and transactions in
      securities issued by the Company, unless earlier (a) revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact or (b) superseded by a new power of attorney regarding the purposes outlined in the first paragraph
      hereof dated as of a later date.</div>
    <div>&#160;</div>
    <div style="text-align: justify; text-indent: 36.1pt;">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 31st day of March, 2025.</div>
    <div>&#160;</div>
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            <div style="text-align: justify; font-weight: normal;">/s/ Cynthia Collins</div>
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          <td style="width: 30%; vertical-align: top;">
            <div style="text-align: justify; font-weight: bold;">Cynthia Collins</div>
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          <td style="width: 20%; vertical-align: top;">&#160;</td>
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    <div>&#160;</div>
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