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Note 15 - Income Taxes - Components of Deferred Tax Assets and Deferred Tax Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Deferred tax assets: |  |
Federal and state net operating losses | $ 79,856 | $ 77,201
Federal and state research and experimentation credits | 13,610 | 12,406
Research and experimental costs | 12,806 | 9,458
Stock based compensation | 1,822 | 1,474
ASC 842 - lease liabilities | 1,303 | 1,468
Accrued compensation | 324 | 610
Fixed asset differences | 191 | 185
Intangible asset differences | 4 | 0
Other | 264 | 59
Total gross deferred tax assets | 110,180 | 102,861
Less valuation allowance | (104,361) | (95,256)
Net deferred tax assets | 5,819 | 7,605
Deferred tax liabilities: |  |
Patent expenditures | (888) | (1,096)
ASC 842 - right of use assets | (795) | (897)
Fixed asset differences | (4) | (9)
Intangible asset differences | (4,132) | (5,603)
Total gross deferred tax liabilities | (5,819) | (7,605)
Total net deferred tax assets and liabilities | $ 0 | $ 0

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