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Commitments and Contingencies - Additional Information (Details) | 12 Months Ended
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Dec. 31, 2019 USD ($) Faculty | Dec. 31, 2018 USD ($) shares
Commitments and Contingencies [Line Items] |  |
Research and development expense | $ 11,671,000 | $ 4,467,000
Manufacturing agreements, maximum amount committed | $ 1,300,000 |
Common Stock |  |
Commitments and Contingencies [Line Items] |  |
Number of shares issued, shares | shares |  | 33,670
Operating Lease Agreement |  |
Commitments and Contingencies [Line Items] |  |
Operating lease, description | The lease term commenced in May 2019 and will expire in July 2022. |
Lease commencement period | 2019-05 |
Lease expiration period | 2022-07 |
Initial annual base rent | $ 261,000 |
Percentage of annual increase of base rent | 2.00% |
Rent expense | $ 178,000 |
Penn Agreement |  |
Commitments and Contingencies [Line Items] |  |
Obligation to be paid | $ 2,000,000 |
Payment term | 3 years |
Payment commencement date | 2018-08 |
License maintenance fee | $ 10,000 |
Total milestone payments | 20,000,000 |
Amounts due to agreement | 0 |
Penn Agreement | Common Stock |  |
Commitments and Contingencies [Line Items] |  |
Number of shares issued, shares | shares |  | 481,318
Penn Agreement | Research and Development | Common Stock |  |
Commitments and Contingencies [Line Items] |  |
Number of shares issued, value |  | $ 1,155,000
Penn Agreement | General and Administrative Expense |  |
Commitments and Contingencies [Line Items] |  |
Out-of-pocket expenses reimbursed |  | 89,000
Sponsored Research Agreements | Penn |  |
Commitments and Contingencies [Line Items] |  |
Obligation to be paid | $ 8,524,000 |
Number of faculty member | Faculty | 2 |
Funding term | 3 years |
Funding term end date | 2021-04 |
Research and development expense | $ 2,137,000 | 1,957,000
Sponsored Research Agreements | Penn | Prepaid Expenses and Other Current Assets |  |
Commitments and Contingencies [Line Items] |  |
Advance payments | 1,588,000 | $ 884,000
Master Translational Research Services Agreement |  |
Commitments and Contingencies [Line Items] |  |
Research and development expense | 2,355,000 |
Maximum research and development expenses through the remaining term | 900,000 |
Master Translational Research Services Agreement | Accrued Liabilities |  |
Commitments and Contingencies [Line Items] |  |
Obligation to be paid | 94,000 |
Subscription and Technology Transfer Agreement |  |
Commitments and Contingencies [Line Items] |  |
Research and development expense | $ 250,000 |

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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 985 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 + Details
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