<SEC-DOCUMENT>0001104659-23-103241.txt : 20230922
<SEC-HEADER>0001104659-23-103241.hdr.sgml : 20230922
<ACCEPTANCE-DATETIME>20230922171753
ACCESSION NUMBER:		0001104659-23-103241
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20230922
DATE AS OF CHANGE:		20230922

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INNOVATIVE SOLUTIONS & SUPPORT INC
		CENTRAL INDEX KEY:			0000836690
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMPUTER PROGRAMMING SERVICES [7371]
		IRS NUMBER:				232507402
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			0930

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-267595
		FILM NUMBER:		231272467

	BUSINESS ADDRESS:	
		STREET 1:		720 PENNSYLVANIA DRIVE
		CITY:			EXTON
		STATE:			PA
		ZIP:			19341
		BUSINESS PHONE:		610 646 9800

	MAIL ADDRESS:	
		STREET 1:		720 PENNSYLVANIA DRIVE
		CITY:			EXTON
		STATE:			PA
		ZIP:			19341
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>tm2326706d1_424b5.htm
<DESCRIPTION>424B5
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<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: right"><B>Filed Pursuant to Rule&nbsp;424(b)(5)&nbsp;<BR>
Registration No.&nbsp;333-267595</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.5in"><B>PROSPECTUS
SUPPLEMENT</B>&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.5in"><B>(To Prospectus
dated October&nbsp;14, 2022)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><IMG SRC="tm2326706d1_424b5img01.jpg" ALT=""></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Up to $40,000,000 of Common Stock</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">We have entered into a Sales Agreement (the &ldquo;Sales
Agreement&rdquo;) with Stifel, Nicolaus&nbsp;&amp; Company,&nbsp;Incorporated (&ldquo;Stifel&rdquo;, and collectively with any other such
agents as may be designated by us from time to time, the &ldquo;Agents&rdquo; and each, an &ldquo;Agent&rdquo;), as sales agent, relating
to the shares of our common stock, par value $0.001 per share, offered by this prospectus supplement and the accompanying prospectus.
In accordance with the terms of the Sales Agreement, we may, from time to time, issue and sell shares of our common stock having an aggregate
offering price of up to $40,000,000 through or to the Agents. All references to &ldquo;Agents&rdquo; in this prospectus supplement refer
initially to Stifel, and thereafter to Stifel and such other agents as may be designated by us from time to time in the future.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Our common stock is currently listed on The Nasdaq
Global Select Market (&ldquo;Nasdaq&rdquo;) under the trading symbol &ldquo;ISSC&rdquo;. On September&nbsp;21, 2023, the last reported
sale price of our common stock was $7.81 per share.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Sales of the common stock, if any, made by the
Agents, as our sales agents, as contemplated by this prospectus supplement and the accompanying prospectus, may be made by means of transactions
that are deemed to be &ldquo;at the market offerings&rdquo; as defined in Rule&nbsp;415 under the Securities Act of 1933, as amended (the
 &ldquo;Securities Act&rdquo;). Accordingly, an indeterminate number of shares of our common stock may be sold, if any, but in no event
will we issue and sell common stock with an aggregate sales price of more than $40,000,000 pursuant to the Sales Agreement. We will pay
each Agent, acting as sales agent, an aggregate commission of up to 3.0% of the gross sales price per share of our common stock sold through
such Agent, under the Sales Agreement. In connection with the sale of shares of our common stock on our behalf, the Agents will be deemed
to be &ldquo;underwriters&rdquo; within the meaning of the Securities Act, and the compensation of the Agents will be deemed to be underwriting
commissions or discounts.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Agents are not required to sell any specific
number or dollar amount of our common stock but will use their commercially reasonable efforts, consistent with their normal sales and
trading practice, as our sales agent, and on the terms and subject to the conditions of the Sales Agreement, to sell the common stock
offered on terms agreed by the Agents and us. We cannot predict the number of shares that we may sell hereby or if any shares will be
sold. There is no arrangement for funds to be received in an escrow, trust or similar arrangement. The net proceeds we receive from the
sale of shares of our common stock to which this prospectus supplement relates will be the gross proceeds received from such sales less
the commissions or discounts and any other expenses we may incur in issuing the shares of our common stock. See &ldquo;Use of Proceeds&rdquo;
and &ldquo;Plan of Distribution&rdquo; for further information.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><B>Investing in our securities involves risks.
You should carefully consider the risks described or referred to under &ldquo;Risk Factors&rdquo; on page&nbsp;S-4 of this prospectus
supplement and on page&nbsp;4 of the accompanying prospectus, in our most recent Annual Report on Form&nbsp;10-K and any subsequent Quarterly
Reports on Form&nbsp;10-Q (which descriptions are incorporated by reference herein) and any amendment or update thereto reflected in subsequent
filings with the U.S. Securities and Exchange Commission (&ldquo;SEC&rdquo;) and incorporated by reference in this prospectus supplement
and the accompanying prospectus, as well as in the other information contained or incorporated by reference in this prospectus supplement
hereto and the accompanying prospectus, before making a decision to invest in our securities.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Neither the SEC nor any state securities commission
has approved or disapproved of these securities or determined that this prospectus is truthful or complete. Any representation to the
contrary is a criminal offense.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><IMG SRC="tm2326706d1_424b5img03.jpg" ALT="">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">The date of this prospectus supplement is September&nbsp;22,
2023</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>TABLE OF CONTENTS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>PROSPECTUS SUPPLEMENT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font: 10pt Times New Roman, Times, Serif">
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_001">ABOUT THIS PROSPECTUS SUPPLEMENT</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_001"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-ii</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_002">SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_002"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-ii</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_003">PROSPECTUS
    SUPPLEMENT SUMMARY</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_003"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-1</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_004">THE
    OFFERING</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_004">S-3</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_005">RISK
    FACTORS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_005"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-4</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_006">USE OF PROCEEDS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_006"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-6</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_007">PLAN OF DISTRIBUTION</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_007"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-6</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_008">LEGAL MATTERS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_008"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-7</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_009">EXPERTS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_009"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-7</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_010">WHERE
    YOU CAN FIND MORE INFORMATION</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_010"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-7</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_011">INCORPORATION
    OF CERTAIN DOCUMENTS BY REFERENCE</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_011"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">S-8</FONT></A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD COLSPAN="3" STYLE="font: bold 10pt Times New Roman, Times, Serif; text-align: center"><A HREF="#a_024">PROSPECTUS</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 86%; text-align: left"><A HREF="#a_012">ABOUT
    THIS PROSPECTUS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 2%">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 12%; text-align: right"><A HREF="#a_012">1</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_013">PROSPECTUS
    SUMMARY</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_013">2</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_014">RISK
    FACTORS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_014">4</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_015">CAUTIONARY
    NOTE REGARDING FORWARD-LOOKING STATEMENTS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_015">4</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_016">USE OF PROCEEDS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_016">6</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_017">DESCRIPTION
    OF OUR COMMON STOCK</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_017">7</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_018">PLAN OF DISTRIBUTION</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_018">10</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_019" STYLE="-sec-extract: exhibit">LEGAL
    MATTERS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_019" STYLE="-sec-extract: exhibit">13</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_020">EXPERTS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_020">13</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_021">DISCLOSURE
    OF COMMISSION POSITION ON INDEMNIFICATION</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_021">13</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#XXX_001" STYLE="-sec-extract: exhibit"><FONT STYLE="text-transform: uppercase">Where You Can Find
    More Information</FONT></A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#XXX_001" STYLE="-sec-extract: exhibit">14</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_023">DOCUMENTS
    INCORPORATED BY REFERENCE</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_023">14</A></TD></TR>
  </TABLE>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>You should rely only on the information contained in or incorporated
by reference in this prospectus supplement and the accompanying prospectus. We have not authorized anyone to provide you with different
information. We are not making an offer of these securities in any state or jurisdiction where the offer is not permitted. You should
not assume that the information contained in this prospectus supplement and the accompanying prospectus is accurate as of any date other
than the date on the front of this prospectus supplement.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_001"></A>ABOUT THIS PROSPECTUS SUPPLEMENT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">This prospectus supplement is a supplement to the
accompanying prospectus that is also a part of this document. This prospectus supplement and the accompanying prospectus are part of a
registration statement on Form&nbsp;S-3 that we filed with the Securities and Exchange Commission using a &ldquo;shelf&rdquo; registration
process. This prospectus supplement and the accompanying prospectus contain specific information about us and the terms on which we are
offering and selling shares of our common stock. To the extent that any statement made in this prospectus supplement is inconsistent with
statements made in the prospectus, the statements made in the prospectus will be deemed modified or superseded by those made in this prospectus
supplement. Before you purchase shares of our common stock, you should carefully read this prospectus supplement, the accompanying prospectus
and the registration statement, together with the documents incorporated by reference in this prospectus supplement and the accompanying
prospectus.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">You should rely only on the information incorporated
by reference or set forth in this prospectus supplement and the accompanying prospectus. We have not authorized anyone else to provide
you with additional or different information. You should not assume that the information in this prospectus supplement, the accompanying
prospectus or any other offering material is accurate as of any date other than the dates on the front of those documents.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">References in this prospectus supplement to &ldquo;we,&rdquo;
 &ldquo;us,&rdquo; &ldquo;our,&rdquo; &ldquo;IS&amp;S&rdquo; or the &ldquo;Company&rdquo; are to Innovative Solutions and Support,&nbsp;Inc.
Unless otherwise defined herein, certain capitalized terms used in this prospectus supplement have the meaning ascribed to them in the
accompanying prospectus.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_002"></A>SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><I>This prospectus supplement
contains forward-looking statements within the meaning of the federal securities laws. These forward-looking statements are based largely
on current expectations and projections about future events and trends affecting the business, are not guarantees of future performance,
and involve a number of risks, uncertainties and assumptions that are difficult to predict. In this prospectus supplement, the words &ldquo;anticipates,&rdquo;
 &ldquo;believes,&rdquo; &ldquo;may,&rdquo; &ldquo;will,&rdquo; &ldquo;estimates,&rdquo; &ldquo;continues,&rdquo; &ldquo;anticipates,&rdquo;
 &ldquo;intends,&rdquo; &ldquo;forecasts,&rdquo; &ldquo;expects,&rdquo; &ldquo;plans,&rdquo; &ldquo;could,&rdquo; &ldquo;should,&rdquo;
 &ldquo;would,&rdquo; &ldquo;is likely&rdquo; and similar expressions, as they relate to the business or to its management, are intended
to identify forward-looking statements, but they are not exclusive means of identifying them. Unless the context otherwise requires, all
references herein to &ldquo;IS&amp;S,&rdquo; the &ldquo;Company,&rdquo; &ldquo;we,&rdquo; &ldquo;us&rdquo; or &ldquo;our&rdquo; are to
Innovative Solutions and Support,&nbsp;Inc. and its consolidated subsidiaries.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>The
forward-looking statements in this prospectus supplement are only predictions, and actual events or results may differ materially. In
evaluating such statements, a number of risks, uncertainties and other factors could cause actual results, performance, financial condition,
cash flows, prospects and opportunities to differ materially from those expressed in, or implied by, the forward-looking statements. These
risks, uncertainties and other factors include those set forth in</I></FONT> <FONT STYLE="font-size: 10pt">&ldquo;</FONT><I>Risk Factors&rdquo;
on page&nbsp;S-4 of this prospectus supplement, in our most recent Annual Report on Form&nbsp;10-K and any subsequent Quarterly Reports
on Form&nbsp;10-Q (which descriptions are incorporated by reference herein) and any amendment or update thereto reflected in subsequent
filings with the U.S. Securities and Exchange Commission, and the following factors:</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>market
    acceptance of the Company&rsquo;s ThrustSense&reg; full-regime Autothrottle, Vmc</I></FONT><I><FONT STYLE="font-size: 10pt"><SUB>a
    </SUB></FONT>Mitigation, FPDS, NextGen Flight Deck and COCKPIT/IP&reg; or other planned products or product enhancements;</I></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>continued
    market acceptance of the Company&rsquo;s air data systems and products;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    competitive environment and new product offerings from competitors;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>difficulties
    in developing, producing or improving the Company&rsquo;s planned products or product enhancements;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    deferral or termination of programs or contracts for convenience by customers;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    ability to service the international market;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    availability of government funding;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    availability and efficacy of vaccines (including vaccine boosters) and their global deployment in response to the COVID-19 pandemic
    (including as a result of the impact of any newer variants or strains of SARS-CoV-2);</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    impact of general economic trends on the Company&rsquo;s business, including as a result of inflation and rising interest rates;</I></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>disruptions
    in the Company&rsquo;s supply chain, customer base and workforce, including as a result of the COVID-19 pandemic;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    ability to gain regulatory approval of products in a timely manner;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>delays
    in receiving components from third-party suppliers;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    bankruptcy or insolvency of one or more key customers;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>protection
    of intellectual property rights;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    ability to respond to technological change;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>failure
    to retain/recruit key personnel;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>risks
    related to succession planning;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>a cyber
    security incident;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>risks
    related to our self-insurance program;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>ability
    to successfully manage and integrate key acquisitions, mergers, and other transactions, such as the recent asset acquisition of certain
    Inertial, Communication and Navigation product lines from Honeywell International,&nbsp;Inc., as well as the failure to realize expected
    synergies and benefits anticipated when we make an acquisition;</I></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>potential
    future acquisitions or dispositions;</I></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    costs of compliance with present and future laws and regulations;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>changes
    in law, including changes to corporate tax laws in the United States and the availability of certain tax credits; and</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>other
    factors disclosed from time to time in the Company&rsquo;s filings with the SEC.</I></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><I>Except as expressly required
by the federal securities laws, the Company undertakes no obligation to publicly update or revise any forward-looking statements, whether
as a result of new information, future events, or otherwise after the date of this prospectus. Results of operations in any past period
should not be considered indicative of the results to be expected for future periods. Fluctuations in operating results may result in
fluctuations in the price of the Company&rsquo;s common stock.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><I>Readers are cautioned not
to place undue reliance on these forward-looking statements, which speak only as of the date of this prospectus. The Company does not
undertake any obligation to publicly release any revisions to these forward-looking statements to reflect events, circumstances or changes
in expectations after the date of this prospectus, or to reflect the occurrence of unanticipated events. The forward-looking statements
in this prospectus are intended to be subject to the safe harbor protection provided by Sections 27A of the Securities Act of 1933, as
amended (the &ldquo;Securities Act&rdquo;), and 21E of the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;).</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><I>Investors should also be
aware that while the Company, from time to time, communicates with securities analysts, it is against its policy to disclose any material
non-public information or other confidential commercial information. Accordingly, shareholders should not assume that the Company agrees
with any statement or report issued by any analyst irrespective of the content of the statement or report. Furthermore, the Company has
a policy against issuing or confirming financial forecasts or projections issued by others. Thus, to the extent that reports issued by
securities analysts contain any projections, forecasts or opinions, such reports are <B><U>not</U></B> the responsibility of the Company.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_003"></A>PROSPECTUS SUPPLEMENT SUMMARY</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><I>This summary highlights selected information
contained in this prospectus supplement. It does not contain all of the information that you should consider before investing in our common
stock. You should read carefully the more detailed information in our Registration Statement on Form&nbsp;S-3 of which this prospectus
supplement and the accompanying prospectus form a part, our most recent Annual Report on Form&nbsp;10-K and any subsequent Quarterly Reports
on Form&nbsp;10-Q (which descriptions are incorporated by reference herein), as well as the other information contained or incorporated
by reference in this prospectus supplement before making a decision to invest in our common stock.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Overview</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Innovative Solutions and Support,&nbsp;Inc. (the
 &ldquo;Company,&rdquo; &ldquo;IS&amp;S,&rdquo; &ldquo;we&rdquo; or &ldquo;us&rdquo;) operates in one business segment as a systems integrator
that designs, develops, manufactures, sells and services air data equipment, engine display systems, standby equipment, primary flight
guidance, autothrottles and cockpit display systems for retrofit applications and original equipment manufacturers (&ldquo;OEMs&rdquo;).
The Company supplies integrated Flight Management Systems (&ldquo;FMS&rdquo;), Flat Panel Display Systems (&ldquo;FPDS&rdquo;), FPDS with
Autothrottle, air data equipment,&nbsp;Integrated Standby Units (&ldquo;ISU&rdquo;),&nbsp;ISU with Autothrottle and advanced GPS receivers
that enable reduced carbon footprint navigation.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Company has continued to position itself as
a system integrator, which capability provides the Company with the potential to generate more substantive orders over a broader product
base. This strategy, as both a manufacturer and integrator, is designed to leverage the latest technologies developed for the computer
and telecommunications industries into advanced and cost-effective solutions for the general aviation, commercial air transport, United
States Department of Defense (&ldquo;DoD&rdquo;)/governmental and foreign military markets. This approach, combined with the Company&rsquo;s
industry experience, is designed to enable IS&amp;S to develop high-quality products and systems, to reduce product time to market, and
to achieve cost advantages over products offered by its competitors.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">For several years the Company has been working
with advances in technology to provide pilots with more information to enhance both the safety and efficiency of flying, and has developed
its COCKPIT/IP&reg; Cockpit Information Portal (&ldquo;CIP&rdquo;) product line, that incorporates proprietary technology, low cost, reduced
power consumption, decreased weight, and increased functionality. The Company has incorporated Electronic Flight Bag functionality, such
as charting and mapping systems, into its FPDS product line.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Company has developed an FMS that combines
the savings long associated with in-flight fuel optimization in enroute flight management combined with the precision of satellite-based
navigation required to comply with the regulatory environments of both domestic and international markets. The Company believes that the
FMS, alongside its FPDS and CIP product lines, is well suited to address market demand driven by certain regulatory mandates, new technologies,
and the high cost of maintaining aging and obsolete equipment on aircraft that will be in service for up to fifty years. The shift in
the regulatory and technological environment is illustrated by the dramatic increase in the number of Space Based Augmentation System
(&ldquo;SBAS&rdquo;) or Wide Area Augmentation System (&ldquo;WAAS&rdquo;) approach qualified airports, particularly as realized through
Localizer Performance with Vertical guidance (&ldquo;LPV&rdquo;) navigation procedures. Aircraft equipped with the Company&rsquo;s FMS,
FPDS and SBAS/WAAS/LPV enabled navigator, will be qualified to land at such airports and will comply with Federal Aviation Administration
(&ldquo;FAA&rdquo;) mandates for Required Navigation Performance, and Automatic Dependent Surveillance-Broadcast navigation. IS&amp;S
believes this will further increase the demand for the Company&rsquo;s products. The Company&rsquo;s FMS/FPDS product line is designed
for new production and retrofit applications into general aviation, commercial air transport and military transport aircraft. In addition,
the Company offers what we believe to be a state-of-the-art ISU, integrating the full functionality of the primary and navigation displays
into a small backup-powered unit. This ISU builds on the Company&rsquo;s legacy air data computer to form a complete next-generation cockpit
display and navigation upgrade offering to the commercial and military markets.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Company has developed and received certification
from the FAA on its NextGen Flight Deck featuring its ThrustSense&reg; Integrated PT6 Autothrottle (&ldquo;ThrustSense&reg; Autothrottle&rdquo;)
for retrofit in the Pilatus PC-12. The NextGen Flight Deck features Primary Flight and Multi-Function Displays and ISUs, as well as an
Integrated FMS and EFB System. The innovative avionics suite includes dual flight management systems, autothrottles, synthetic vision
and enhanced vision. The NextGen enhanced avionics suite is available for integration into other business aircraft with Non-FADEC and
FADEC engines.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

</DIV>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Company has developed its FAA-certified ThrustSense&reg;
Autothrottle for retrofit in the King Air, dual turbo prop PT6 powered aircraft. The autothrottle is designed to automate the power management
for speed and power control including go-around. ThrustSense&reg; also ensures aircraft envelope protection and engine protection during
all phases of flight thereby reducing pilot workload and increasing safety. The Company has signed a multi-year agreement with Textron
Aviation,&nbsp;Inc. (&ldquo;Textron&rdquo;) to supply ThrustSense&reg; on the King Air 360 and King Air 260. ThrustSense&reg; is also
available for retrofit on King Airs aircraft through Textron service centers and third-party service centers. The Company has also developed
an FAA-certified safety mode feature for its King Airs aircraft ThrustSense&reg; Autothrottle, LifeGuard&trade;, which provides critical
Vmca protection that proportionally reduces engine power to maintain directional control during an engine-out condition.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">We believe the ThrustSense&reg; Autothrottle is
innovative in that it is the first autothrottle developed for a turbo prop that allows a pilot to automatically control the power setting
of the engine. The autothrottle computes and controls appropriate power levels, thereby reducing overall pilot workload. The system computes
thrust, holds selected speed/torque, and implements appropriate speed and engine limit protection. When engaged by the pilot, the autothrottle
system adjusts the throttles automatically to achieve and hold the selected airspeed guarded by a torque/temperature limit mode. The autothrottle
system takes full advantage of the integrated cockpit and utilizes weight and balance information to determine optimal control settings
and enable safety functions like a turbulence control mode.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Company sells to both the OEM and the retrofit
markets. Customers include various OEMs, commercial air transport carriers and corporate/general aviation companies, DoD and its commercial
contractors, aircraft operators, aircraft modification centers, government agencies, and foreign militaries. Occasionally,&nbsp;IS&amp;S
sells its products directly to DoD; however, the Company sells its products primarily to commercial customers for end use in DoD programs.
Sales to defense contractors are generally made on commercial terms, although some of the termination and other provisions of government
contracts are applicable to these contracts. The Company&rsquo;s retrofit projects are generally pursuant to either a direct contract
with a customer or a subcontract with a general contractor to a customer (including government agencies).</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">On the other hand, the Company believes that in
adverse economic conditions, customers that may have otherwise elected to purchase newly manufactured aircraft may be interested instead
in retrofitting existing aircraft as a cost-effective alternative, thereby creating a market opportunity for IS&amp;S.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">On June&nbsp;30, 2023, the Company entered into
an Asset Purchase and License Agreement with Honeywell International,&nbsp;Inc. (&ldquo;Honeywell&rdquo;) whereby Honeywell sold, certain
assets and granted perpetual license rights to manufacture and sell licensed products related to its inertial, communication and navigation
product lines to the Company (the &ldquo;Transaction&rdquo;). The Transaction involved a sale of certain inventory, equipment and customer-related
documents; an assignment of certain customer contracts; and a grant of exclusive and non-exclusive licenses to use certain Honeywell intellectual
property related to its inertial, communication and navigation product lines to repair, overhaul, manufacture sell, import, export and
distribute certain products to the Company. Concurrent with the Transaction, the Company entered into a transition services agreement
with Honeywell, at no additional costs, to receive certain transitional services and technical support during the transition service period.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Corporate Information</B></P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Company was incorporated in Pennsylvania on
February&nbsp;12, 1988. Our principal executive office is located at 720 Pennsylvania Drive, Exton, Pennsylvania 19341, and our telephone
number is (610) 646-9800. Our website address is http://www.innovative-ss.com. No information found on our website is part of this prospectus.
Also, this prospectus may include the names of various government agencies or the trade names of other companies. Unless specifically
stated otherwise, the use or display by us of such other parties&rsquo; names and trade names in this prospectus is not intended to and
does not imply a relationship with, or endorsement or sponsorship of us by, any of these other parties.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

</DIV>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_004"></A>THE OFFERING</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt; width: 22%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Issuer</FONT></TD>
    <TD STYLE="width: 2%">&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt; width: 76%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Innovative Solutions and Support,&nbsp;Inc. </FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Common Stock Offered by Us</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Shares of our common stock representing an aggregate offering price of up to $40,000,000.</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Manner of Offering</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&ldquo;At the market offering,&rdquo; as defined in Rule&nbsp;415 promulgated under the Securities Act, that may be made from time to time through or to Stifel as sales agent using commercially reasonable efforts. See the section entitled &ldquo;Plan of Distribution&rdquo; on page&nbsp;S-6 in this prospectus supplement.</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Use of Proceeds</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">We plan to use the net proceeds from this offering for general corporate purposes, which may include, among other things, repayment or refinancing of outstanding debt, financing acquisitions or investments, product development, and general working capital purposes. See the section entitled &ldquo;Use of Proceeds&rdquo; on page&nbsp;S-6 in this prospectus supplement.</FONT></TD></TR>
  <TR>
    <TD STYLE="vertical-align: top; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; vertical-align: bottom; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Listing</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Our common stock is currently traded on Nasdaq under the symbol &ldquo;ISSC.&rdquo;</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Risk Factors</FONT></TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify; padding-top: 1.5pt; padding-right: 1.25pt; padding-left: 1.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Investing in our common stock involves risks. You should carefully read and consider the risks described or referred to under &ldquo;Risk Factors&rdquo; beginning on page&nbsp;S-4 of this prospectus supplement and on page&nbsp;4 of the accompanying prospectus, in our most recent Annual Report on Form&nbsp;10-K and any subsequent Quarterly Reports on Form&nbsp;10-Q (which descriptions are incorporated by reference herein), as well as in the other information contained or incorporated by reference in this prospectus supplement, before making a decision to invest in our common stock.</FONT></TD></TR>
  </TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

</DIV>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_005"></A>RISK FACTORS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in"><I>In evaluating an investment in our common stock,
you should carefully consider the following risk factors and the risk factors described under the caption &ldquo;Risk Factors&rdquo; in
the accompanying prospectus, our most recent Annual Report on Form&nbsp;10-K and any subsequent Quarterly Reports on Form&nbsp;10-Q (which
descriptions are incorporated by reference herein), and any amendment or update thereto reflected in subsequent filings with the SEC and
incorporated by reference in this prospectus supplement and the accompanying prospectus, as well as in the other information contained
or incorporated by reference in this prospectus supplement and the accompanying prospectus and any amendment or update to our risk factors
reflected in subsequent filings with the SEC, before making a decision to invest in our securities.</I></P>

<P STYLE="text-align: left; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0"><B><I>You may experience immediate dilution in the book value per share
of the common stock you purchase in this offering.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">The price per share of our common stock in this
offering may exceed the net tangible book value per share of our common stock outstanding prior to this offering. Therefore, if you purchase
shares of our common stock in this offering, you may pay a price per share that substantially exceeds our net tangible book value per
share after this offering.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0"><B><I>You may experience future dilution as a result of future issuances
of shares of our common stock or securities convertible into or exchangeable for our common stock.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">To raise additional capital, we may in the future
offer additional shares of our common stock or other securities convertible into or exchangeable for our common stock at prices that may
not be the same as the price per share in this offering. <FONT STYLE="background-color: white">We may sell shares or other securities
in any other offering at a price per share that is less than the price per share paid by investors in this offering, and investors purchasing
shares or other securities in the future could have rights superior to existing shareholders. </FONT>In addition, the exercise of outstanding
stock options could result in further dilution of your investment.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0"><B><I>The common stock offered under this prospectus supplement and
the accompanying prospectus may be sold in &ldquo;at the market offerings,&rdquo; and investors who buy shares at different times will
likely pay different prices.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">Investors who purchase shares under this prospectus
supplement and the accompanying prospectus at different times will likely pay different prices, and so may experience different outcomes
in their investment results. We will have discretion, subject to market demand, to vary the timing, prices, and numbers of shares sold.
Investors may experience declines in the value of their shares as a result of share sales made at prices lower than the prices they paid.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; background-color: white"><B><I>A&nbsp;large number of shares may be
sold in the market following this offering, which may depress the market price of our common stock.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">Sales
of a substantial number of shares of our common stock in the public market following this offering could cause the market price of our
common stock to decline. If there are more shares of common stock offered for sale than buyers are willing to purchase, then the market
price of our common stock may decline to a market price at which buyers are willing to purchase the offered shares of common stock and
sellers remain willing to sell the shares. All of the shares sold in this offering will be freely tradable without restriction or further
registration under the Securities Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0"><B><I>We will have broad discretion in the use of the net proceeds
to us from this offering; we may not use the offering proceeds that we receive effectively.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">Our management will have broad discretion in the
application of the net proceeds from this offering and could spend the proceeds in ways that do not improve our business, financial condition,
or results of operations. You may not agree with our decisions, and our use of the proceeds may not yield any return on your investment.
We intend to use the proceeds from this offering for general corporate purposes. Our general corporate purposes may include, among other
things, repayment or refinancing of outstanding debt, financing acquisitions or investments, product development, and general working
capital purposes. We have not determined the amount of net proceeds to be used specifically for the foregoing purposes. As a result, our
management will have broad discretion over the allocation of the net proceeds.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="background-color: white">Because of
the number and variability of factors that will determine our use of the net proceeds from this offering, their ultimate use may vary
substantially from their currently intended use. Our failure to apply the net proceeds of this offering effectively could compromise our
ability to pursue our growth strategy, and we might not be able to yield a significant return, if any, on our investment of these net
proceeds. You will not have the opportunity to influence our decisions on how to use the net proceeds from this offering. The failure
by our management to apply these funds effectively could result in financial losses that could harm our business and cause the price of
our common stock to decline. Pending their use, we may invest the net proceeds from this offering in a manner that does not produce income
or that loses value.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white"><B><I>We are selling
the securities offered in this prospectus on a &ldquo;best efforts&rdquo; basis and may not be able to sell any of the securities offered
herein.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">We
have engaged the agents to act as sales agents in connection with this offering. While the agents will use their reasonable best efforts
to arrange for the sale of the securities, they are under no obligation to purchase any of the securities. As a result, there are no firm
commitments to purchase any of the securities in this offering. Consequently, there is no guarantee that we will be capable of selling
all, or any, of the securities being offered hereby.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B><I>It is not possible to predict the actual number of shares we
will sell under the Sales Agreement, or the gross proceeds resulting from those sales.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">Subject to certain limitations in the Sales Agreement
and compliance with applicable law, we have the discretion to deliver a placement notice to the sales agent at any time throughout the
term of the Sales Agreement. The number of shares that are sold through the sales agent after delivering a placement notice will fluctuate
based on a number of factors, including the market price of the common stock during the sales period, the limits we set with the sales
agent in any applicable placement notice, and the demand for our common stock during the sales period. Because the price per share of
each share sold will fluctuate during the sales period, it is not currently possible to predict the number of shares that will be sold
or the gross proceeds to be raised in connection with those sales, if any.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; background-color: white"><B><I>Our common stock may be affected by
limited trading volume and may fluctuate significantly.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">Our
common stock is traded on Nasdaq. Although an active trading market has developed for our common stock, there can be no assurance that
an active trading market for our common stock will be sustained. Failure to maintain an active trading market for our common stock may
adversely affect our shareholders&rsquo; ability to sell our common stock in short time periods, or at all. Our common stock has experienced,
and may experience in the future, significant price and volume fluctuations, which could adversely affect the market price of our common
stock.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0"><B><I>Our common stock has experienced and may continue to experience
price fluctuations, which could cause you to lose a significant portion of your investment and interfere with our efforts to grow our
business.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">Stock markets are subject to significant price
fluctuations that may be unrelated to the operating performance of particular companies, and accordingly the market price of our common
stock may frequently and meaningfully change. In addition, the market price of our common stock has fluctuated and may continue to fluctuate
substantially due to a variety of other factors. Possible exogenous incidents and trends may also impact the capital markets generally
and our common stock prices specifically. For example, the ongoing war between Russia and Ukraine and resulting economic sanctions imposed
by many countries on Russia have led to disruption, instability and volatility in the U.S. and global markets and industries and are expected
to have a negative impact on the U.S. and broader global economies. The timing of your purchase and sale of our common stock relative
to fluctuations in its trading price may result in you losing a significant portion of your investment.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; background-color: white"><B><I>Because we do not intend to declare
cash dividends on our shares of common stock in the foreseeable future, shareholders must rely on appreciation of the value of our common
stock for any return on their investment.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">We
currently anticipate that we will retain future earnings for the development, operation and expansion of our business and do not anticipate
declaring or paying any cash dividends in the foreseeable future. In addition, the terms of any future debt agreements may preclude us
from paying dividends. As a result, we expect that only appreciation of the price of our common stock, if any, will provide a return to
investors in this offering for the foreseeable future.</P>

<P STYLE="text-align: left; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_006"></A>USE OF PROCEEDS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">We currently intend to use the net proceeds from
the sale of the securities described in this prospectus supplement for general corporate purposes. Our general corporate purposes may
include, among other things, repayment or refinancing of outstanding debt, financing acquisitions or investments, product development,
and general working capital purposes. We have not determined the amount of net proceeds to be used specifically for such purposes. As
a result, management will retain broad discretion over the allocation of net proceeds.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_007"></A>PLAN OF DISTRIBUTION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">Under the terms of the Sales Agreement, we may,
from time to time, propose to issue and sell our common stock having an aggregate offering price of up to $40,000,000 through or to the
Agents, as agent or principal. Pursuant to the Sales Agreement, we may add new Agents as parties to the Sales Agreement in the future
with the consent of such new Agents, but without the consent of the other Agents.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">Sales, if any, of our
common stock made through or to the Agents, as our sales agent or principal, as contemplated by this prospectus supplement and the
accompanying prospectus, may be made by means of transactions that are deemed to be &ldquo;at the market offerings&rdquo; as defined
in Rule&nbsp;415 under the Securities Act, including sales made directly on or through The Nasdaq Global Select Market or any other
existing trading market for shares of our common stock, in negotiated transactions at market prices prevailing at the time of sale
or at prices related to such prevailing market prices and/or any other method permitted by law.</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">The Agents are not required to sell any specific
number or dollar amount of our common stock but have agreed to use their commercially reasonable efforts, consistent with their normal
trading and sales practices, on the terms and subject to the conditions of the Sales Agreement, to sell the common stock offered on terms
agreed upon by the Agents and us. If we choose to offer our common stock, we will instruct the Agent as to the number of shares to be
sold by them, the minimum or average minimum price per share and the date or dates on which such shares are to be sold. We may instruct
the Agents not to sell our common stock if the sales cannot be effected at or above a price designated by us. The Agents may decline to
accept any such instructions that we may provide to them from time to time. We or the Agents may suspend the offering of common stock
by the Agents upon notice to the other party.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">If shares of our common stock are sold by the Agents
in an at the market offering, the Agents have agreed to confirm to us in writing the number of shares sold on the applicable trading day
and the related gross sales price and net sales price of those shares on the immediately following trading day. We will report at least
quarterly the number of shares of our common stock sold through the Agents under the Sales Agreement, information concerning the net proceeds
from those sales and the aggregate compensation paid to the Agents with respect to such sales.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">The Agents will not engage in any transactions
that stabilize or maintain the market price of our common stock in connection with any offers or sales of our common stock as our sales
agent pursuant to the Sales Agreement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">We will pay each Agent acting as our sales agent
an aggregate commission of up to 3.0% of the gross sales price per share of common stock sold through such Agent, under the Sales Agreement.
The remaining sales proceeds, after deducting any transaction fees, transfer taxes or similar taxes or fees imposed by any governmental,
regulatory or self-regulatory organization in respect of the sale of the common stock, will be our net proceeds (before the expenses referred
to in the next paragraph) from the sale of the common stock in the offering. We have also agreed to reimburse the Agents for certain specified
expenses, including the fees and disbursements of its legal counsel in an amount not to exceed $75,000, as provided in the Sales Agreement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">We estimate that the total expenses payable by
us in connection with the establishment of the program to offer our common stock described in this prospectus supplement, excluding commissions
and any discounts payable to the Agents and any other deductions described in the paragraph above, will be approximately $200,000.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">We will not issue common stock having aggregate
sales proceeds of more than $40,000,000 pursuant to the Sales Agreement. We cannot predict the number of shares that we may sell hereby
or if any shares will be sold.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">Settlement for sales of shares in return for payment
of the net proceeds to us is expected to occur on the second business day that is also a trading day following the trade date on which
such sales were made, in either case unless another date shall be agreed to in writing by us and the Agents. There is no arrangement for
funds to be received in an escrow, trust or similar arrangement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">The offering of common stock pursuant to the Sales
Agreement will terminate upon the earlier of (1)&nbsp;the sale of all of the common stock subject to the Sales Agreement and (2)&nbsp;the
termination of the Sales Agreement by us or the Agents. The Sales Agreement may be terminated either by us or the Agents upon the giving
of ten (10)&nbsp;days prior written notice to the other party and in the sole discretion of us or the Agents, as the case may be.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">We have agreed to provide indemnification and contribution
to the Agents against certain liabilities, including liabilities under the Securities Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">The Agents shall be under no obligation to purchase
our shares on a principal basis pursuant to the Sales Agreement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">In connection with the sale of common stock on
our behalf, the Agents will be deemed to be &ldquo;underwriters&rdquo; within the meaning of the Securities Act, and the compensation
paid to the Agents will be deemed to be underwriting commissions or discounts. The Agents shall have no obligation to offer or sell any
of our shares in the event such an offer or sale of the shares as agents on our behalf may, in the reasonable judgment of the Agents,
constitute a &ldquo;distribution&rdquo; within the meaning of Rule&nbsp;100 of Regulation M or the Agents reasonably believe they may
be deemed an &ldquo;underwriter&rdquo; within the meaning of the Securities Act in a transaction that is other than by means of ordinary
brokers&rsquo; transactions on Nasdaq that qualify for delivery of a prospectus to Nasdaq in accordance with Rule&nbsp;153 of the Securities
Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_008"></A>LEGAL MATTERS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">Certain legal matters will be passed upon for us
by Holland&nbsp;&amp; Knight LLP, Miami, Florida. Goodwin Procter LLP, New York, New York, will act as legal counsel to the Agents.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_009"></A>EXPERTS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The audited financial statements of Innovative Solutions &amp; Support, Inc. and subsidiaries as of September 30, 2022 and 2021, incorporated
by reference in this prospectus supplement and elsewhere in the registration statement have been so incorporated by reference in reliance
upon the report of Grant Thornton LLP, independent registered public accountants, upon the authority of said firm as experts in accounting
and auditing.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The audited abbreviated financial statements of the Acquired Honeywell Product Lines (the &ldquo;Product Lines&rdquo;), which comprise
the statements of assets acquired as of December 31, 2022 and 2021, and the statements of revenue and direct expenses for the year ended
December 31, 2022 and 2021, incorporated by reference in this prospectus supplement and elsewhere in the registration statement have been
so incorporated by reference in reliance upon the report of Grant Thornton LLP, independent certified public accountants, upon the authority
of said firm as experts in accounting and auditing.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_010"></A>WHERE YOU CAN FIND MORE INFORMATION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">We have filed a registration statement, of which
this prospectus supplement is a part, covering the securities offered hereby. As allowed by SEC rules, this prospectus supplement does
not contain all of the information set forth in the registration statement and the exhibits thereto. We refer you to the registration
statement and the exhibits thereto for further information. This prospectus supplement is qualified in its entirety by such other information.
Our SEC filings, including our registration statement, are also available to you on the SEC&rsquo;s website at <U>www.sec.gov</U><I>.
</I>We file reports, proxy statements and other information with the SEC as required by the Exchange Act. Those reports, proxy statements
and other information are available on the SEC&rsquo;s website referred to above.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">We maintain a website on the Internet with the
address of <U>https://innovative-ss.com/</U><I>. </I>We are not incorporating by reference into this prospectus supplement the information
on our website, and you should not consider our website to be a part of this prospectus supplement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_011"></A>INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">The SEC&rsquo;s rules&nbsp;allow us to &ldquo;incorporate
by reference&rdquo; information into this prospectus supplement filed separately with the SEC. The information incorporated by reference
is deemed to be part of this prospectus supplement from the date of filing those documents. Any reports filed by us with the SEC on or
after the date of this prospectus supplement will automatically update and, where applicable, supersede any information contained in this
prospectus supplement or incorporated by reference in this prospectus supplement. We have filed the documents listed below with the SEC
under the Exchange Act, and these documents are incorporated herein by reference (other than information in such documents that is furnished
and not deemed to be filed):</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></FONT></TD><TD STYLE="text-align: justify"><A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922127805/issc-20220930x10k.htm" STYLE="-sec-extract: exhibit">Our Annual Report on Form&nbsp;10-K for the year ended September&nbsp;30, 2022, filed on December&nbsp;16, 2023</A>;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify">Our Quarterly Reports on Form&nbsp;10-Q for the quarter ended June&nbsp;30, 2023, filed on <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000141057823001775/issc-20230630x10q.htm" STYLE="-sec-extract: exhibit">August&nbsp;11, 2023</A>; the quarter ended
March&nbsp;31, 2023, filed on <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465923057210/issc-20221231x10q.htm" STYLE="-sec-extract: exhibit">May, 8, 2023</A>; and the quarter ended December&nbsp;31, 2022, filed on <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465923021519/issc-20221231x10q.htm" STYLE="-sec-extract: exhibit">February&nbsp;14, 2023</A>;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify">Our Current Reports on Form&nbsp;8-K or Form&nbsp;8-K/A, as applicable, filed <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465923079122/tm2320694d1_8k.htm" STYLE="-sec-extract: exhibit">July&nbsp;7, 2023</A> (as amended on <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465923100499/tm2325955d1_8ka.htm" STYLE="-sec-extract: exhibit">September&nbsp;13, 2023</A> and <A HREF="http://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465923100920/tm2325955d2_8ka.htm" STYLE="-sec-extract: exhibit">September&nbsp;15, 2023</A>), <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465923046322/tm2312632d1_8k.htm" STYLE="-sec-extract: exhibit">April&nbsp;18, 2023</A>, and <A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465923097744/tm2325393d1_8k.htm" STYLE="-sec-extract: exhibit">September&nbsp;1, 2023</A>;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><A HREF="https://www.sec.gov/Archives/edgar/data/836690/000110465923025332/tm234015-2_def14a.htm" STYLE="-sec-extract: exhibit">The portions of our Definitive Proxy Statement on Schedule 14A, for our 2023 Annual Meeting of Shareholders filed with the SEC on February&nbsp;24, 2023; and</A></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify"><A HREF="https://www.sec.gov/Archives/edgar/data/836690/000103605000001339/0001036050-00-001339-0001.txt" STYLE="-sec-extract: exhibit">The description of our common stock contained in our Registration Statement on Form&nbsp;8-A, filed with the SEC on July&nbsp;26, 2000 to register such common stock under the Exchange Act.</A></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">All documents we file pursuant to Sections 13(a),
13(c), 14 or 15(d)&nbsp;of the Exchange Act on or after the date of this prospectus supplement and prior to the termination of the offering
of the securities to which this prospectus supplement relates (other than information in such documents that is furnished and not deemed
to be filed) shall be deemed to be incorporated by reference into this prospectus supplement and to be a part hereof from the date of
filing of those documents. All documents we file pursuant to Sections 13(a), 13(c), 14 or 15(d)&nbsp;of the Exchange Act after the date
of the initial registration statement that contains the accompanying prospectus and prior to the effectiveness of the registration statement
shall be deemed to be incorporated by reference into the prospectus and to be a part hereof from the date of filing those documents.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: justify; margin: 0pt 0; text-indent: 0.5in">We will provide to each person, including any beneficial
owner, to whom a copy of this prospectus supplement is delivered, a copy of any or all of the information that has been incorporated by
reference in this prospectus supplement but not delivered with this prospectus supplement (other than the exhibits to such documents which
are not specifically incorporated by reference therein); we will provide this information at no cost to the requester upon written or
oral request to: Chief Financial Officer,&nbsp;Innovative Solutions and Support,&nbsp;Inc., 720 Pennsylvania Drive, Exton, Pennsylvania
19341, or (610) 646-9800.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_024"></A>PROSPECTUS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Innovative Solutions and Support,&nbsp;Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>$100,000,000 of Common Stock</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Innovative Solutions and Support,&nbsp;Inc., a
Pennsylvania corporation (the &ldquo;<U>Company</U>,&rdquo; &ldquo;<U>IS&amp;S</U>,&rdquo; &ldquo;<U>we</U>&rdquo; or &ldquo;<U>us</U>&rdquo;)
may offer and sell from time to time, in one or more series or issuances and on terms that we will determine at the time of the offering,
shares of our common stock, par value $0.001 per share (&ldquo;<U>Common Stock</U>&rdquo;) described in this prospectus, up to an aggregate
amount of $100,000,000.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This prospectus provides you with a general description
of the securities offered. Each time we offer and sell securities, we will file a prospectus supplement to this prospectus that contains
specific information about the offering and, if applicable, the amounts, prices and terms of the securities. Such supplements may also
add, update or change information contained in this prospectus. You should carefully read this prospectus and the applicable prospectus
supplement before you invest in any of our securities. This prospectus may not be used to consummate sales of securities unless accompanied
by a prospectus supplement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We may offer and sell the securities described
in this prospectus and any prospectus supplement directly to our stockholders or to other purchasers or through agents on our behalf or
through underwriters or dealers as designated from time to time. If any agents or underwriters are involved in the sale of any of these
securities, the applicable prospectus supplement will provide the names of the agents or underwriters and any applicable fees, commission
or discounts.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Our Common Stock is currently quoted on The Nasdaq
Global Select Market under the trading symbol &ldquo;ISSC&rdquo;. On September&nbsp;22, 2022, the last reported sale price of our Common
Stock was $9.01 per share.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Investing in our securities involves a high
degree of risk. See the section entitled &ldquo;Risk Factors&rdquo; on page&nbsp;4 of this prospectus and in the documents we filed with
the U.S. Securities and Exchange Commission that are incorporated in this prospectus by reference for certain risks and uncertainties
you should consider.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Neither the U.S. Securities and Exchange Commission
nor any state securities commission has approved or disapproved of these securities or passed upon the adequacy or accuracy of this prospectus.
Any representation to the contrary is a criminal offense.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>This prospectus is dated October&nbsp;14, 2022.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>TABLE OF CONTENTS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font: 10pt Times New Roman, Times, Serif">
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 86%; text-align: left"><A HREF="#a_012">ABOUT THIS PROSPECTUS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 2%">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 12%; text-align: right"><A HREF="#a_012">1</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_013">PROSPECTUS SUMMARY</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_013">2</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_014">RISK FACTORS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_014">4</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_015">CAUTIONARY NOTE REGARDING FORWARD-LOOKING
    STATEMENTS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_015">4</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_016">USE OF PROCEEDS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_016">6</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_017">DESCRIPTION OF OUR COMMON STOCK</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_017">7</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_018">PLAN OF DISTRIBUTION</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_018">10</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_019">LEGAL MATTERS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_019">13</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif"><A HREF="#a_020">EXPERTS</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_020">13</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_021">DISCLOSURE OF COMMISSION POSITION ON INDEMNIFICATION</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_021">13</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#XXX_001"><FONT STYLE="text-transform: uppercase">Where You Can Find
    More Information</FONT></A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#XXX_001">14</A></TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt">&nbsp;</TD><TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="text-align: right; font-size: 10pt">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left"><A HREF="#a_023">DOCUMENTS INCORPORATED BY REFERENCE</A></TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right"><A HREF="#a_023">14</A></TD></TR>
  </TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_012"></A>ABOUT THIS PROSPECTUS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">This prospectus of Innovative
Solutions and Support,&nbsp;Inc., a Pennsylvania corporation (collectively with all of its subsidiaries, the &ldquo;<U>Company</U>,&rdquo;
 &ldquo;<U>IS&amp;S</U>,&rdquo; &ldquo;<U>we</U>&rdquo; or &ldquo;<U>us</U>&rdquo;) is a part of a registration statement on Form&nbsp;S-3
that we filed with the U.S. Securities and Exchange Commission (the &ldquo;<U>SEC</U>&rdquo;) utilizing a &ldquo;shelf&rdquo; registration
process. Under this shelf registration process, we may, from time to time, sell the securities described in this prospectus in one or
more offerings up to a total dollar amount of $100,000,000 as described in this prospectus.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The registration statement
of which this prospectus is a part provides additional information about us and the securities offered under this prospectus. The registration
statement, including the exhibits and the documents incorporated herein by reference, can be read on the SEC website or at the SEC offices
mentioned under the heading &ldquo;Where You Can Find More Information.&rdquo;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">We will provide a prospectus
supplement containing specific information about the amounts, prices and terms of the securities for a particular offering. The prospectus
supplement may add, update or change information in this prospectus. If the information in the prospectus is inconsistent with a prospectus
supplement, you should rely on the information in that prospectus supplement. You should read both this prospectus and, if applicable,
any prospectus supplement. See &ldquo;Where You Can Find More Information&rdquo; for more information.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">You should rely only on the
information contained or incorporated by reference in this prospectus and in any prospectus supplement. We have not authorized any other
person to provide you with different information. If anyone provides you with different or inconsistent information, you should not rely
on it. We are not making offers to sell or solicitations to buy the securities in any jurisdiction in which an offer or solicitation is
not authorized or in which the person making that offer or solicitation is not qualified to do so or to anyone to whom it is unlawful
to make an offer or solicitation. You should not assume that the information in this prospectus or any prospectus supplement, as well
as the information we file or previously filed with the SEC that we incorporate by reference in this prospectus or any prospectus supplement,
is accurate as of any date other than the date of such document. Our business, financial condition, results of operations and prospects
may have changed since those dates.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B><A NAME="a_013"></A>PROSPECTUS
SUMMARY</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B><I>The items in the following summary are described
in more detail later in this prospectus. This summary does not contain all of the information you should consider. Before investing in
our securities, you should read the entire prospectus carefully, including the &ldquo;Risk Factors&rdquo; beginning on page&nbsp;4 and
the financial statements incorporated by reference.</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Company Overview</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">Innovative
Solutions and Support,&nbsp;Inc. (the &ldquo;<U>Company</U>,&rdquo; &ldquo;<U>IS&amp;S</U>,&rdquo; &ldquo;<U>we</U>&rdquo; or &ldquo;<U>us</U>&rdquo;)
operates in one business segment as a systems integrator that designs, develops, manufactures, sells and services air data equipment,
engine display systems, standby equipment, primary flight guidance, autothrottles and cockpit display systems for retrofit applications
and original equipment manufacturers (&ldquo;<U>OEMs</U>&rdquo;). The Company supplies integrated Flight Management Systems (&ldquo;<U>FMS</U>&rdquo;),
Flat Panel Display Systems (&ldquo;<U>FPDS</U>&rdquo;), FPDS with Autothrottle, air data equipment,&nbsp;Integrated Standby Units (&ldquo;<U>ISU</U>&rdquo;),&nbsp;ISU
with Autothrottle and advanced GPS receivers that enable reduced carbon footprint navigation.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">The
Company has continued to position itself as a system integrator, which capability provides the Company with the potential to generate
more substantive orders over a broader product base. This strategy, as both a manufacturer and integrator, is designed to leverage the
latest technologies developed for the computer and telecommunications industries into advanced and cost-effective solutions for the general
aviation, commercial air transport, United States Department of Defense (&ldquo;<U>DoD</U>&rdquo;)/governmental and foreign military markets.
This approach, combined with the Company&rsquo;s industry experience, is designed to enable IS&amp;S to develop high-quality products
and systems, to reduce product time to market, and to achieve cost advantages over products offered by its competitors.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">For
several years the Company has been working with advances in technology to provide pilots with more information to enhance both the safety
and efficiency of flying, and has developed its COCKPIT/IP&reg; Cockpit Information Portal (&ldquo;<U>CIP</U>&rdquo;) product line, that
incorporates proprietary technology, low cost, reduced power consumption, decreased weight, and increased functionality. The Company has
incorporated Electronic Flight Bag (&ldquo;<U>EFB</U>&rdquo;) functionality, such as charting and mapping systems, into its FPDS product
line.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">The
Company has developed an FMS that combines the savings long associated with in-flight fuel optimization in enroute flight management combined
with the precision of satellite-based navigation required to comply with the regulatory environments of both domestic and international
markets. The Company believes that the FMS, alongside its FPDS and CIP product lines, is well suited to address market demand driven by
certain regulatory mandates, new technologies, and the high cost of maintaining aging and obsolete equipment on aircraft that will be
in service for up to fifty years. The shift in the regulatory and technological environment is illustrated by the dramatic increase in
the number of Space Based Augmentation System (&ldquo;<U>SBAS</U>&rdquo;) or Wide Area Augmentation System (&ldquo;<U>WAAS</U>&rdquo;)
approach qualified airports, particularly as realized through Localizer Performance with Vertical guidance (&ldquo;<U>LPV</U>&rdquo;)
navigation procedures. Aircraft equipped with the Company&rsquo;s FMS, FPDS and SBAS/WAAS/LPV enabled navigator, will be qualified to
land at such airports and will comply with Federal Aviation Administration (&ldquo;<U>FAA</U>&rdquo;) mandates for Required Navigation
Performance, and Automatic Dependent Surveillance-Broadcast navigation. IS&amp;S believes this will further increase the demand for the
Company&rsquo;s products. The Company&rsquo;s FMS/FPDS product line is designed for new production and retrofit applications into general
aviation, commercial air transport and military transport aircraft. In addition, the Company offers what we believe to be a state-of-the-art
ISU, integrating the full functionality of the primary and navigation displays into a small backup-powered unit. This ISU builds on the
Company&rsquo;s legacy air data computer to form a complete next-generation cockpit display and navigation upgrade offering to the commercial
and military markets.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">The
Company has developed and received certification from the FAA on its NextGen Flight Deck featuring its ThrustSense&reg; Integrated PT6
Autothrottle (&ldquo;<U>ThrustSense&reg; Autothrottle</U>&rdquo;) for retrofit in the Pilatus PC-12. The NextGen Flight Deck features
Primary Flight and Multi-Function Displays and ISUs, as well as an Integrated FMS and EFB System. The innovative avionics suite includes
dual flight management systems, autothrottles, synthetic vision and enhanced vision. The NextGen enhanced avionics suite is available
for integration into other business aircraft with Non-FADEC and FADEC engines.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">The
Company has developed its FAA-certified ThrustSense&reg; Autothrottle for retrofit in the King Air, dual turbo prop PT6 powered aircraft.
The autothrottle is designed to automate the power management for speed and power control including go-around. ThrustSense&reg; also ensures
aircraft envelope protection and engine protection during all phases of flight reducing pilot workload and increasing safety. The Company
has signed a multi-year agreement with Textron Aviation,&nbsp;Inc. (&ldquo;<U>Textron</U>&rdquo;) to supply ThrustSense&reg; on the King
Air 360 and King Air 260. ThrustSense&reg; is also available for retrofit on King Airs through Textron service centers and third-party
service centers. The Company has also developed an FAA-certified safety mode feature for its King Air ThrustSense&reg; Autothrottle, LifeGuard&trade;,
which provides critical Vmca protection that proportionally reduces engine power to maintain directional control during an engine-out
condition.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">We
believe the ThrustSense&reg; Autothrottle is innovative in that it is the first autothrottle developed for a turbo prop that allows a
pilot to automatically control the power setting of the engine. The autothrottle computes and controls appropriate power levels, thereby
reducing overall pilot workload. The system computes thrust, holds selected speed/torque, and implements appropriate speed and engine
limit protection. When engaged by the pilot, the autothrottle system adjusts the throttles automatically to achieve and hold the selected
airspeed guarded by a torque/temperature limit mode. The autothrottle system takes full advantage of the integrated cockpit utilizing
weight and balance information for optimal control settings and enabling safety functions like a turbulence control mode.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">The
Company sells to both the OEM and the retrofit markets. Customers include various OEMs, commercial air transport carriers and corporate/general
aviation companies, DoD and its commercial contractors, aircraft operators, aircraft modification centers, government agencies, and foreign
militaries. Occasionally,&nbsp;IS&amp;S sells its products directly to DoD; however, the Company sells its products primarily to commercial
customers for end use in DoD programs. Sales to defense contractors are generally made on commercial terms, although some of the termination
and other provisions of government contracts are applicable to these contracts. The Company&rsquo;s retrofit projects are generally pursuant
to either a direct contract with a customer or a subcontract with a general contractor to a customer (including government agencies).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Corporate Information</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Company was incorporated
in Pennsylvania on February&nbsp;12, 1988. Our principal executive office is located at 720 Pennsylvania Drive, Exton, Pennsylvania 19341,
and our telephone number is (610) 646-9800. Our website address is http://www.innovative-ss.com. No information found on our website is
part of this prospectus. Also, this prospectus may include the names of various government agencies or the trade names of other companies.
Unless specifically stated otherwise, the use or display by us of such other parties&rsquo; names and trade names in this prospectus is
not intended to and does not imply a relationship with, or endorsement or sponsorship of us by, any of these other parties.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_014"></A>RISK FACTORS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><I>An investment in our Common
Stock involves significant risks. You should carefully consider the risk factors contained in this prospectus and in our filings with
the SEC, as well as all of the information contained in any prospectus supplement, free writing prospectus and amendments thereto, before
you decide to invest in our Common Stock. Our business, prospects, financial condition and results of operations may be materially and
adversely affected as a result of any of such risks. The value of our Common Stock could decline as a result of any of these risks. You
could lose all or part of your investment in our Common Stock. Some of our statements in sections entitled &ldquo;Risk Factors&rdquo;
are forward-looking statements. The risks and uncertainties we have described are not the only ones we face. Additional risks and uncertainties
not presently known to us or that we currently deem immaterial may also affect our business, prospects, financial condition and results
of operations.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_015"></A>CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><I>This prospectus contains forward-looking statements
within the meaning of the federal securities laws. These forward-looking statements are based largely on current expectations and projections
about future events and trends affecting the business, are not guarantees of future performance, and involve a number of risks, uncertainties
and assumptions that are difficult to predict. In this prospectus, the words &ldquo;anticipates,&rdquo; &ldquo;believes,&rdquo; &ldquo;may,&rdquo;
 &ldquo;will,&rdquo; &ldquo;estimates,&rdquo; &ldquo;continues,&rdquo; &ldquo;anticipates,&rdquo; &ldquo;intends,&rdquo; &ldquo;forecasts,&rdquo;
 &ldquo;expects,&rdquo; &ldquo;plans,&rdquo; &ldquo;could,&rdquo; &ldquo;should,&rdquo; &ldquo;would,&rdquo; &ldquo;is likely&rdquo; and
similar expressions, as they relate to the business or to its management, are intended to identify forward-looking statements, but they
are not exclusive means of identifying them. Unless the context otherwise requires, all references herein to &ldquo;<U>IS&amp;S</U>,&rdquo;
the &ldquo;<U>Registrant</U>,&rdquo; the &ldquo;<U>Company</U>,&rdquo; &ldquo;<U>we</U>,&rdquo; &ldquo;<U>us</U>&rdquo; or &ldquo;<U>our</U>&rdquo;
are to Innovative Solutions and Support,&nbsp;Inc. and its consolidated subsidiaries.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><I>The forward-looking statements in this prospectus
are only predictions, and actual events or results may differ materially. In evaluating such statements, a number of risks, uncertainties
and other factors could cause actual results, performance, financial condition, cash flows, prospects and opportunities to differ materially
from those expressed in, or implied by, the forward-looking statements. These risks, uncertainties and other factors include those set
forth in Item&nbsp;1A (Risk Factors) of our Annual Report on Form&nbsp;10-K for the fiscal&nbsp;year ended September&nbsp;30, 2021 and
the following factors:</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>market
    acceptance of the Company&rsquo;s ThrustSense&reg; full-regime Autothrottle, Vmc</I></FONT><I><FONT STYLE="font-size: 10pt"><SUB>a
    </SUB></FONT>Mitigation, FPDS, NextGen Flight Deck and COCKPIT/IP&reg; or other planned products or product enhancements;</I></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>continued
    market acceptance of the Company&rsquo;s air data systems and products;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    competitive environment and new product offerings from competitors;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>difficulties
    in developing, producing or improving the Company&rsquo;s planned products or product enhancements;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    deferral or termination of programs or contracts for convenience by customers;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    ability to service the international market;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    availability of government funding;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    availability and efficacy of vaccines (including vaccine boosters) and their global deployment in response to the COVID-19 pandemic
    (including as a result of the impact of any newer variants or strains of SARS-CoV-2);</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    impact of general economic trends on the Company&rsquo;s business, including as a result of inflation and rising interest rates;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>disruptions
    in the Company&rsquo;s supply chain, customer base and workforce, including as a result of the COVID-19 pandemic;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    ability to gain regulatory approval of products in a timely manner;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>delays
    in receiving components from third-party suppliers;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    bankruptcy or insolvency of one or more key customers;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>protection
    of intellectual property rights;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    ability to respond to technological change;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>failure
    to retain/recruit key personnel;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>risks
    related to succession planning;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>a cyber
    security incident;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>risks
    related to our self-insurance program;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>potential
    future acquisitions;</I></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>the
    costs of compliance with present and future laws and regulations;</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>changes
    in law, including changes to corporate tax laws in the United States and the availability of certain tax credits; and</I></FONT></TD></TR>

<TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>other
    factors disclosed from time to time in the Company&rsquo;s filings with the U.S. Securities and Exchange Commission (the &ldquo;<U>SEC</U>&rdquo;).</I></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><I>Except as expressly required by the federal
securities laws, the Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result
of new information, future events, or otherwise after the date of this prospectus. Results of operations in any past period should not
be considered indicative of the results to be expected for future periods. Fluctuations in operating results may result in fluctuations
in the price of the Company&rsquo;s common stock.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><I>Readers are cautioned not to place undue reliance
on these forward-looking statements, which speak only as of the date of this prospectus. The Company does not undertake any obligation
to publicly release any revisions to these forward-looking statements to reflect events, circumstances or changes in expectations after
the date of this prospectus, or to reflect the occurrence of unanticipated events. The forward-looking statements in this prospectus are
intended to be subject to the safe harbor protection provided by Sections 27A of the Securities Act of 1933, as amended (the &ldquo;<U>Securities
Act</U>&rdquo;), and 21E of the Securities Exchange Act of 1934, as amended (the &ldquo;<U>Exchange Act</U>&rdquo;).</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><I>Investors should also be aware that while the
Company, from time to time, communicates with securities analysts, it is against its policy to disclose any material non-public information
or other confidential commercial information. Accordingly, shareholders should not assume that the Company agrees with any statement or
report issued by any analyst irrespective of the content of the statement or report. Furthermore, the Company has a policy against issuing
or confirming financial forecasts or projections issued by others. Thus, to the extent that reports issued by securities analysts contain
any projections, forecasts or opinions, such reports are <B><U>not</U></B> the responsibility of the Company.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_016"></A>USE OF PROCEEDS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Unless otherwise specified
in the applicable prospectus supplement, we intend to use the net proceeds from the sale of the securities described in this prospectus
for growing the businesses of the Company through the acquisition of product lines, companies or businesses and for general corporate
purposes, which may include, among other things, working capital, capital expenditures and other anticipated growth opportunities. The
applicable prospectus supplement will provide more details on the use of proceeds of any specific offering.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_017"></A>DESCRIPTION OF OUR COMMON STOCK</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">The
following description of our Common Stock is based upon our Company&rsquo;s Amended and Restated Articles of Incorporation (the &ldquo;<U>A&amp;R
Charter</U>&rdquo;), as modified by that certain Statement with Respect to Shares for Series&nbsp;B Junior Participating Preferred Stock
(the &ldquo;<U>Statement</U>&rdquo; and, our A&amp;R Charter, as modified by the Statement, the &ldquo;<U>Charter</U>&rdquo;), which was
filed with the Department of State of the Commonwealth of Pennsylvania on September&nbsp;12, 2022, and Amended and Restated Bylaws (the
 &ldquo;<U>Bylaws</U>&rdquo;). The Company&rsquo;s Charter and Bylaws are each incorporated by reference as an exhibit to the <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465921152604/issc-20210930x10k.htm" STYLE="-sec-extract: exhibit">Annual Report on Form&nbsp;10-K for the fiscal year ended September&nbsp;30, 2021 that we filed with the SEC on December&nbsp;22, 2021</A></FONT></FONT>
(the &ldquo;<U>Annual Report</U>&rdquo;). The Statement was filed as an exhibit to the <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922099272/tm2225633d1_8k.htm" STYLE="-sec-extract: exhibit">Current Report on Form&nbsp;8-K that we filed with the SEC on September&nbsp;12, 2022</A></FONT> to disclose our entry into that certain Rights
Agreement (the &ldquo;<U>Rights Agreement</U>&rdquo;), dated September&nbsp;12, 2022, between the Company and Broadridge Corporate Issuer
Solutions,&nbsp;Inc., as Rights Agent.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The following description
is not meant to be a complete description of our Common Stock and is qualified by reference to our Charter, our Bylaws and the Rights
Agreement. For additional information, please read the Company&rsquo;s Charter and Bylaws, the Rights Agreement and the applicable provisions
of the Pennsylvania Business Corporation Law (the &ldquo;<U>PBCL</U>&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>General</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Company&rsquo;s authorized
capital stock consists of (1)&nbsp;75,000,000 shares of Common Stock, $0.001 par value (&ldquo;<U>Common Stock</U>&rdquo;), and (2)&nbsp;10,000,000
shares of Preferred Stock, $0.001 par value, of which 200,000 shares are authorized as Series&nbsp;A Convertible Preferred Stock (&ldquo;<U>Series&nbsp;A
Preferred Stock</U>&rdquo;) and 50,000 shares are authorized as Series&nbsp;B Junior Participating Preferred Stock (&ldquo;<U>Series&nbsp;B
Preferred Stock</U>&rdquo; and, together with the Series&nbsp;A Preferred Stock, &ldquo;<U>Preferred Stock</U>&rdquo;). As of July&nbsp;29,
2022, there were 17,276,213 issued and outstanding shares of Common Stock and no issued or outstanding shares of Preferred Stock.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Preferred Share Purchase Rights</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">On September&nbsp;11, 2022,
the Company&rsquo;s Board of Directors (the &ldquo;<U>Board</U>&rdquo;) declared a dividend of one preferred share purchase right (a &ldquo;<U>Right</U>&rdquo;),
payable on September&nbsp;27, 2022, for each share of Common Stock outstanding on September&nbsp;27, 2022 to the stockholders of record
on that date. Each Right entitles the registered holder to purchase from the Company one one-thousandth of a share of Series&nbsp;B Preferred
Stock at a price of $41.57 per one one-thousandth of a share of Series&nbsp;B Preferred Stock represented by a Right, subject to adjustment.
Each share of Series&nbsp;B Preferred Stock will entitle the holder thereof to the same dividends and liquidation rights as if the holder
held one share of Common Stock and will be treated the same as a share of Common Stock in the event of a merger, consolidation or other
share exchange. Under certain circumstances, as further described in the Rights Agreement, the Rights may be convertible or exchangeable
into shares of Common Stock. Until a Right is exercised, converted or exchanged for shares of the Company&rsquo;s capital stock, the holder
thereof, as such, will have no rights as a stockholder of the Company, including, without limitation, the right to vote or to receive
dividends.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Board declared the dividend
of the Rights and entered into the Rights Agreement in order to promote the fair and equal treatment of all Company stockholders and ensure
that no person or group can gain control of the Company through open market accumulation or other tactics without paying a control premium
and potentially disadvantaging the interests of all stockholders. The issuance of the Rights and the Company&rsquo;s entry into the Rights
Agreement is not intended to deter offers that are fair and otherwise in the best interest of the Company&rsquo;s stockholders.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Voting</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Company does not have
any other classes of voting stock outstanding other Common Stock, but may in the future have outstanding shares of Series&nbsp;B Preferred
Stock in the event any of the Rights are exercised in accordance with the terms of the Rights Agreement. Each share of Common Stock is
entitled to one (1)&nbsp;vote, and share of Series&nbsp;B Preferred Stock is entitled to one thousand (1,000) votes. There are no cumulative
voting rights when voting for directors.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Conversion Rights</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Holders of the Company&rsquo;s
Common Stock do not have conversion rights. Shares of the Company&rsquo;s Series&nbsp;A Preferred Stock can be converted, at the option
of the holder, into fully paid and nonassessable shares of Common Stock pursuant to and in accordance with Art. IV, &sect; B(4)&nbsp;of
the Company&rsquo;s Charter. Shares of the Company&rsquo;s Series&nbsp;B Preferred Stock can, under certain circumstances, be converted
into or exchange for fully paid and nonassessable shares of Common Stock pursuant to and in accordance with the Statement and the Rights
Agreement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Preemptive and Redemption Rights</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Stockholders do not have (1)&nbsp;preemptive
rights to purchase additional shares of the Company&rsquo;s capital stock (except as may be expressly set forth in a separate agreement
between the Company and one or more holders of Preferred Stock) or (2)&nbsp;redemption rights.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Dividends</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The declaration and payment
of any dividends is within the discretion of the Board.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Liquidation and Dissolution</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">In the event of any liquidation,
dissolution or winding up of the Company, the holders of the Company&rsquo;s Common Stock are entitled to share ratably in all assets
remaining after payment of liabilities, subject to prior distribution rights of Preferred Stock, if any, then outstanding, including the
rights of the holders of shares of Series&nbsp;B Preferred Stock to receive $1,000 per share, plus an amount equal to accrued and unpaid
dividends and distributions thereon, whether or not declared, to the date of such payment, before any distribution of assets to the holders
of the Company&rsquo;s Common Stock.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Listing</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Company&rsquo;s Common
Stock is listed on The Nasdaq Global Select Market under the symbol &ldquo;ISSC&rdquo;.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Securities Authorized for Issuance Under Equity
Compensation Plans</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The Company has two share-based
compensation plans: (1)&nbsp;the 2009 Stock-Based Incentive Compensation Plan, which terminated with respect to the grant of any new awards
on January&nbsp;20, 2019, and (2)&nbsp;the 2019 Stock-Based Incentive Compensation Plan, under which 100,000 stock options have been granted
as of September&nbsp;23, 2022. For the complete terms of each of the foregoing share-based compensation plans, please refer to the copies
thereof which are incorporated by reference as exhibits to our Annual Report.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><B>Anti-Takeover Provisions of the Company&rsquo;s
Charter and Bylaws and Pennsylvania Law</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Some sections of the Company&rsquo;s
Charter and Bylaws and provisions of Pennsylvania law may discourage certain transactions involving a change in control of the Company.
For example, the PBCL permits the Board to consider the interests of constituencies other than the shareholders when deciding what will
be in the best interests of the Company. In addition, under the Company&rsquo;s Charter, the Board has the power to alter, amend, and
repeal the Company&rsquo;s Bylaws without shareholder approval, except as to any subjects that are expressly committed to the shareholders
by the terms of the Company&rsquo;s Bylaws, by Section&nbsp;1504 of the PBCL or otherwise.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Certain other provisions of
the Company&rsquo;s Charter and Bylaws could have the effect of preventing or delaying a change in control of the Company, including (1)&nbsp;the
advance notification procedures governing certain shareholder nominations of candidates for the Board and for certain other shareholder
business to be conducted at an annual meeting, (2)&nbsp;the absence of authority for shareholders to call special shareholders meetings,
except as may be required by law, and (3)&nbsp;the absence of authority for shareholder action by written consent, except as may be required
by law. In particular, certain provisions in the Statement (together with certain aspects of the Rights) could have the effect of preventing
or delaying a change in control of the Company that is not approved by the Board.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">While as of June&nbsp;30,
2022, the end of our most recently completed fiscal quarter, no shares of authorized Preferred Stock are currently outstanding, the Company&rsquo;s
Charter permits the Board to, without shareholder approval, establish and issue classes of Preferred Stock with voting, conversion or
other rights that could dilute the voting power or rights of the holders of the Company&rsquo;s Common Stock. For example, the shares
of Series&nbsp;B Preferred Stock issuable upon exercise of the Rights have superior voting rights compared to shares of Common Stock.
The issuance of Preferred Stock such as the Series&nbsp;B Preferred Stock, while potentially providing flexibility in connection with
possible acquisitions and other corporate purposes, could, among other things, have the effect of preventing or delaying a change in control
of the Company and may adversely affect the market price of the Company&rsquo;s Common Stock and the voting and other rights of the holders
of the Company&rsquo;s Common Stock.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_018"></A>PLAN OF DISTRIBUTION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">We may sell the securities
described in this prospectus on a continuous or delayed basis directly to purchasers, through underwriters, broker-dealers or agents that
may receive compensation in the form of discounts, concessions or commissions from us or the purchasers of the securities, in &ldquo;at
the market offerings&rdquo; within the meaning of Rule&nbsp;415(a)(4)&nbsp;of the Securities Act, to or through a market maker or into
an existing trading market, on an exchange, or otherwise or through a combination of any such methods of sale. Discounts, concessions
or commissions as to any particular underwriter, broker-dealer or agent may be in excess of those customary in the types of transactions
involved.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The securities may be sold
from time to time in one or more transactions at fixed prices, which may be changed from time to time, at prevailing market prices at
the time of sale, at varying prices determined at the time of sale or at negotiated prices. These sales may be effected in transactions,
which may involve crosses or block transactions:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">on any national securities exchange or quotation service on which the securities may be listed or quoted at the time of sale;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">in the over-the-counter market;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">in transactions otherwise than on these exchanges or services or in the over-the-counter market; or</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">through the writing or settlement of options or other hedging transactions, whether the options are listed on an options exchange or otherwise.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">in private transactions and transactions otherwise than on these exchanges or systems;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">through underwriters for resale to the public or investors;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">in &ldquo;at the market&rdquo; offerings, within the meaning of Rule&nbsp;415(a)(4)&nbsp;of the Securities Act to or through a market maker or into an existing trading market, on an exchange or otherwise;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">through a combination of any of the above methods; or</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">any other method permitted by law.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Each time that we use this
prospectus to sell our securities, we shall also provide a prospectus supplement. For each series of securities, the applicable prospectus
supplement will set forth the terms of the offering including:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the public offering price;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the name or names of any underwriters, dealers or agents;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the purchase price of the securities;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the proceeds from the sale of the securities to us;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">any underwriting discounts, agency fees, or other compensation payable to underwriters or agents;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">any discounts or concessions allowed or reallowed or repaid to dealers;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the terms of any indemnification provisions, including indemnification from liabilities under the federal securities laws;</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the nature of any transaction by an underwriter, dealer or agent during the offering that is intended to stabilize or maintain the market price of the securities; and</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 24px; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">the securities exchanges on which the securities will be listed, if any.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in"></P>

<!-- Field: Page; Sequence: 24 -->
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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in; text-align: justify; text-indent: -0.25in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">If we use underwriters in
the sale of securities, the securities will be acquired by the underwriters for their own account. The underwriters may then resell the
securities in one or more transactions at a fixed public offering price or at varying prices determined at the time of sale or thereafter.
The securities may be either offered to the public through underwriting syndicates represented by managing underwriters, or directly by
underwriters. The obligations of the underwriters to purchase the securities will be subject to certain conditions. The underwriters will
be obligated to purchase all the securities offered if they purchase any securities. The public offering price and any discounts or concessions
allowed or re-allowed or paid to dealers may be changed from time to time.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">If we use dealers in the sale
of securities, we will sell securities to such dealers as principals. The dealers may then resell the securities to the public at varying
prices to be determined by such dealers at the time of resale. We may solicit offers to purchase the securities directly, and we may sell
the securities directly to institutional or other investors, who may be deemed underwriters within the meaning of the Securities Act with
respect to any resales of those securities. The terms of these sales will be described in the applicable prospectus supplement. If we
use agents in the sale of securities, unless otherwise indicated in the prospectus supplement, they will use their reasonable best efforts
to solicit purchases for the period of their appointment. Unless otherwise indicated in a prospectus supplement, if we sell directly,
no underwriters, dealers or agents would be involved. We will not make an offer of securities in any jurisdiction that does not permit
such an offer.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">We may grant underwriters
who participate in the distribution of securities an option to purchase additional securities to cover overallotments, if any, in connection
with the distribution. Any underwriter may engage in overallotment, stabilizing transactions, short covering transactions and penalty
bids in accordance with SEC orders, rules&nbsp;and regulations and applicable law. To the extent permitted by applicable law and SEC orders,
rules&nbsp;and regulations, an overallotment involves sales in excess of the offering size, which create a short position. Stabilizing
transactions permit bids to purchase the underlying security so long as the stabilizing bids do not exceed a specified maximum. To the
extent permitted by applicable law and SEC orders, rules&nbsp;and regulations, short covering transactions involve purchases of the securities
in the open market after the distribution is completed to cover short positions. Penalty bids permit the underwriters to reclaim a selling
concession from a dealer when the securities originally sold by the dealer is purchased in a covering transaction to cover short positions.
Those activities may cause the price of the Common Stock to be higher than it would otherwise be. If commenced, the underwriters may discontinue
any of the activities at any time.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Any underwriters who are qualified
market makers on The Nasdaq Stock Market may engage in passive market making transactions in our Common Stock on the Nasdaq Stock Market
in accordance with Rule&nbsp;103 of Regulation M, during the business day prior to the pricing of the offering, before the commencement
of offers or sales of the Common Stock. Passive market makers must comply with applicable volume and price limitations and must be identified
as passive market makers. In general, a passive market maker must display its bid at a price not in excess of the highest independent
bid for such security; if all independent bids are lowered below the passive market maker&rsquo;s bid, however, the passive market maker&rsquo;s
bid must then be lowered when certain purchase limits are exceeded. The anti-manipulation rules&nbsp;under the Exchange Act may apply
to sales of shares in the market. Furthermore, Regulation M may restrict the ability of any person engaged in the distribution of the
shares to engage in market-making activities for the particular securities being distributed for a period of up to five business days
before the distribution. The restrictions may affect the marketability of the shares and the ability of any person or entity to engage
in market-making activities for the shares.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Underwriters, dealers and
agents that participate in any distribution of securities may be deemed to be underwriters as defined in the Securities Act. Any discounts,
commissions or profit they receive when they resell the securities may be treated as underwriting discounts and commissions under the
Securities Act. Only underwriters named in the prospectus supplement are underwriters of the securities offered in the prospectus supplement.
We may have agreements with underwriters, dealers and agents to indemnify them against certain civil liabilities, including certain liabilities
under the Securities Act, or to contribute with respect to payments that they may be required to make.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">We may authorize underwriters,
dealers or agents to solicit offers from certain institutions whereby the institution contractually agrees to purchase the securities
from us on a future date at a specific price. This type of contract may be made only with institutions that we specifically approve. Such
institutions could include banks, insurance companies, pension funds, investment companies and educational and charitable institutions.
The underwriters, dealers or agents will not be responsible for the validity or performance of these contracts.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Each series of securities
will be a new issue of securities. Our Common Stock is quoted on The Nasdaq Global Select Market. Unless otherwise specified in the applicable
prospectus supplement, our securities (other than our Common Stock) will not be listed on any exchange. It has not presently been established
whether the underwriters, if any, of the securities will make a market in the securities. If the underwriters make a market in the securities,
such market making may be discontinued at any time without notice.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Agents, dealers and underwriters
may be entitled to indemnification by us against certain civil liabilities, including liabilities under the Securities Act, or to contribution
with respect to payments which the agents, dealers or underwriters may be required to make in respect thereof. Agents, dealers or underwriters
may be customers of, engage in transactions with, or perform services for us and our subsidiaries in the ordinary course of business.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_019"></A>LEGAL MATTERS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The validity of the securities
offered by this prospectus has been passed upon for us by Dechert LLP. If legal matters in connection with offerings made pursuant to
this prospectus are passed upon by counsel for the underwriters, dealers or agents, if any, such counsel will be named in the prospectus
supplement relating to such offering.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_020"></A>EXPERTS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The audited consolidated financial
statements incorporated by reference in this prospectus and elsewhere in the registration statement have been so incorporated by reference
in reliance upon the report of Grant Thornton LLP, independent registered public accountants, upon the authority of said firm as experts
in accounting and auditing.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_021"></A>DISCLOSURE OF COMMISSION POSITION ON INDEMNIFICATION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Insofar as indemnification
for liabilities arising under the Securities Act, as amended, may be permitted to directors, officers, and controlling persons of the
registrant pursuant to the Company&rsquo;s constituent documents, or otherwise, the registrant has been advised that in the opinion of
the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event
that a claim for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a
director, officer, or controlling person in the successful defense of any action, suit, or proceeding) is asserted by such director, officer,
or controlling person connected with the securities being registered, we will, unless in the opinion of our counsel the matter has been
settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against
public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="XXX_001"></A>WHERE YOU CAN FIND MORE INFORMATION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">We are subject to the information
requirements of the Exchange Act. Accordingly, we file annual, quarterly and current reports, proxy statements as may be required and
other information with the SEC and filed a registration statement on Form&nbsp;S-3 under the Securities Act relating to the securities
offered by this prospectus. This prospectus, which forms part of the registration statement, does not contain all of the information included
in the registration statement. For further information, you should refer to the registration statement and its exhibits.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">You can also review our filings
by accessing the website maintained by the SEC at http://www.sec.gov. The site contains reports, proxy and information statements and
other information regarding issuers that file electronically with the SEC. In addition to the foregoing, we maintain a website at http://www.innovative-ss.com.
Our website content is made available for informational purposes only. It should neither be relied upon for investment purposes, nor is
it incorporated by reference into this prospectus. We make available at https://innovative-ss.com/investor-relations/investor-information/
copies of our Annual Reports on Form&nbsp;10-K, Quarterly Reports on Form&nbsp;10-Q and Current Reports on Form&nbsp;8-K and any amendments
to such document as soon as practicable after we electronically file such material with or furnish such documents to the SEC.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><A NAME="a_023"></A>DOCUMENTS INCORPORATED BY REFERENCE</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">The SEC allows us to &ldquo;incorporate
by reference&rdquo; into this prospectus certain information that we file with the SEC, which means that we can disclose important information
to you by referring you to other documents separately filed by us with the SEC that contain such information. The information we incorporate
by reference is considered to be part of this prospectus and information we later file with the SEC will automatically update and supersede
the information in this prospectus. The following documents filed by us with the SEC pursuant to Section&nbsp;13(a)&nbsp;of the Exchange
Act and any of our future filings under Sections 13(a), 13(c), 14 or 15(d)&nbsp;of the Exchange Act, except for information furnished
under Item 2.02 or 7.01 of Current Report on Form&nbsp;8-K, or exhibits related thereto, made before the termination of the offering are
incorporated by reference herein:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465921152604/issc-20210930x10k.htm" STYLE="-sec-extract: exhibit">our Annual Report on Form&nbsp;10 K for the fiscal year ended September&nbsp;30, 2021, filed with the SEC on December&nbsp;22, 2021</A></FONT></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(2)</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922020473/issc-20211231x10q.htm" STYLE="-sec-extract: exhibit">our Quarterly Report on Form&nbsp;10-Q for the quarter ended December&nbsp;31, 2021, filed with the SEC on February&nbsp;11, 2022;</A></FONT></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(3)</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922060309/issc-20220331x10q.htm" STYLE="-sec-extract: exhibit">our Quarterly Report on Form&nbsp;10-Q for the quarter ended March&nbsp;31, 2022, filed with the SEC on May&nbsp;13, 2022</A>;</FONT></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(4)</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922090046/issc-20220630x10q.htm" STYLE="-sec-extract: exhibit">our Quarterly Report on Form&nbsp;10-Q for the quarter ended June&nbsp;30, 2022, filed with the SEC on August&nbsp;12, 2022;</A></FONT></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(5)</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">our Current Reports on Form&nbsp;8-K filed with the SEC on </FONT><FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922004046/tm222925d1_8k.htm" STYLE="-sec-extract: exhibit">January&nbsp;13, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922004442/tm222925d2_8k.htm" STYLE="-sec-extract: exhibit">January&nbsp;14, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922009020/tm224390d1_8k.htm" STYLE="-sec-extract: exhibit">January&nbsp;28, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922032926/tm229003d1_8k.htm" STYLE="-sec-extract: exhibit">March&nbsp;11, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922046069/tm2212784d1_8k.htm" STYLE="-sec-extract: exhibit">April&nbsp;14, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922046121/tm2212784d2_8k.htm" STYLE="-sec-extract: exhibit">April&nbsp;15, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922054619/tm2214210d1_8k.htm" STYLE="-sec-extract: exhibit">May&nbsp;2, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922062334/tm2215946d1_8k.htm" STYLE="-sec-extract: exhibit">May&nbsp;18, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922068980/tm2217891d1_8k.htm" STYLE="-sec-extract: exhibit">June&nbsp;7, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922073520/tm2219152d1_8k.htm" STYLE="-sec-extract: exhibit">June&nbsp;22, 2022</A></FONT>, <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922079167/tm2220705d1_8k.htm" STYLE="-sec-extract: exhibit">July&nbsp;12, 2022</A></FONT> and <FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/836690/000110465922099272/tm2225633d1_8k.htm" STYLE="-sec-extract: exhibit">September&nbsp;12, 2022</A></FONT>; and</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 48px">&nbsp;</TD>
    <TD STYLE="width: 24px; font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(6)</FONT></TD>
    <TD STYLE="font-size: 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><FONT STYLE="color: #0000ee"><A HREF="https://www.sec.gov/Archives/edgar/data/836690/000103605000001339/0001036050-00-001339-0001.txt" STYLE="-sec-extract: exhibit">The description of our Common Stock contained in our Registration Statement on Form&nbsp;8-A, filed with the SEC on July&nbsp;26, 2000 to register such Common Stock under the Exchange Act.</A></FONT></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">In addition, all documents subsequently filed
by us pursuant to Section&nbsp;13(a), 13(c), 14 or 15(d)&nbsp;of the Exchange Act before the date the offering of securities hereunder
is terminated or complete are deemed to be incorporated by reference into, and to be a part of, this prospectus.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We will provide, without charge, to each person,
including any beneficial owner, to whom a prospectus is delivered, a copy of any or all of the reports or documents that have been incorporated
by reference in the prospectus contained in the registration statement but not delivered with the prospectus, other than an exhibit to
these filings unless we have specifically incorporated that exhibit by reference into the filing, upon written or oral request and at
no cost to the requester. Requests should be made by writing or telephoning us at the following address:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Chief Financial Officer</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>720 Pennsylvania Drive<BR>
Exton, Pennsylvania 19341<BR>
(610) 646-9800</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><IMG SRC="tm2326706d1_424b5img02.jpg" ALT=""></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Up
to $40,000,000 of Shares of Common Stock</B></P>



<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Prospectus Supplement</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><IMG SRC="tm2326706d1_424b5img03.jpg" ALT="">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>September&nbsp;22, 2023</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
