<SEC-DOCUMENT>0001420506-25-003518.txt : 20251203
<SEC-HEADER>0001420506-25-003518.hdr.sgml : 20251203
<ACCEPTANCE-DATETIME>20251203134124
ACCESSION NUMBER:		0001420506-25-003518
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251203
DATE AS OF CHANGE:		20251203

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			InfuSystem Holdings, Inc
		CENTRAL INDEX KEY:			0001337013
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				203341405
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-81749
		FILM NUMBER:		251545982

	BUSINESS ADDRESS:	
		STREET 1:		3851 WEST HAMLIN ROAD
		CITY:			ROCHESTER HILLS
		STATE:			MI
		ZIP:			48309
		BUSINESS PHONE:		(248) 291-1210

	MAIL ADDRESS:	
		STREET 1:		3851 WEST HAMLIN ROAD
		CITY:			ROCHESTER HILLS
		STATE:			MI
		ZIP:			48309

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HAPC, Inc.
		DATE OF NAME CHANGE:	20060425

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Healthcare Acquisition Partners Corp.
		DATE OF NAME CHANGE:	20050824

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Minerva Advisors LLC
		CENTRAL INDEX KEY:			0001541536
		ORGANIZATION NAME:           	
		EIN:				753088079

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G

	BUSINESS ADDRESS:	
		STREET 1:		50 MONUMENT ROAD
		STREET 2:		SUITE 201
		CITY:			BALA CYNWYD
		STATE:			PA
		ZIP:			19004
		BUSINESS PHONE:		(484) 434-2258

	MAIL ADDRESS:	
		STREET 1:		50 MONUMENT ROAD
		STREET 2:		SUITE 201
		CITY:			BALA CYNWYD
		STATE:			PA
		ZIP:			19004
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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<!-- Start Form -->
  <formData>
<!-- Issuer Cover Page-->
    <coverPageHeader>
      <securitiesClassTitle>Common Stock, $0.0001 Par Value</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>10/31/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001337013</issuerCik>
        <issuerName>InfuSystem Holdings, Inc.</issuerName>
        <issuerCusip>45685K102</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>3851 WEST HAMLIN ROAD</com:street1>
          <com:city>ROCHESTER HILLS</com:city>
          <com:stateOrCountry>MI</com:stateOrCountry>
          <com:zipCode>48309</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
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        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
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      <reportingPersonName>Minerva Advisors LLC</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>729317</soleVotingPower>
        <sharedVotingPower>296472</sharedVotingPower>
        <soleDispositivePower>729317</soleDispositivePower>
        <sharedDispositivePower>296472</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1025798</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>5.0</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>MINERVA GROUP LP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>729317</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>729317</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>729317</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>3.6</classPercent>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
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    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>MINERVA GP, LP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>729317</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>729317</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>729317</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>3.6</classPercent>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>MINERVA GP, INC.</reportingPersonName>
      <citizenshipOrOrganization>PA</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>729317</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>729317</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>729317</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>3.6</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>COHEN DAVID P</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>729317</soleVotingPower>
        <sharedVotingPower>296472</sharedVotingPower>
        <soleDispositivePower>729317</soleDispositivePower>
        <sharedDispositivePower>296472</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1025798</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>5.0</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
<!-- Items -->
    <items>
      <item1>
        <issuerName>InfuSystem Holdings, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>3851 WEST HAMLIN ROAD, ROCHESTER HILLS, MI, 48309</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Minerva Advisors LLC
Minerva Group, LP
Minerva GP, LP
Minerva GP, Inc.
David P. Cohen</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>50 Monument Road, Suite 201
Bala Cynwyd, PA 19004</principalBusinessOfficeOrResidenceAddress>
        <citizenship>David P. Cohen is a U.S. Citizen.
Minerva Advisors LLC, Minerva Group, LP, and Minerva GP, LP are organized under Delaware law.
Minerva GP, Inc. is organized under Pennsylvania law.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>Minerva Advisors LLC* - 1,025,798
Minerva Group, LP - 729,317
Minerva GP, LP* - 729,317
Minerva GP, Inc.* - 729,317
David P. Cohen* - 1,025,798

*Each of these reporting persons is deemed a beneficial owner of the 729,317 shares of the Issuer held by Minerva Group, LP. David P. Cohen is also deemed a beneficial owner of the 20,336,183 shares of the Issuer beneficially owned by Minerva Advisors LLC.</amountBeneficiallyOwned>
        <classPercent>Minerva Advisors LLC* - 5.0%
Minerva Group, LP - 3.6%
Minerva GP, LP* - 3.6%
Minerva GP, Inc.* - 3.6%
David P. Cohen* - 5.0%

*Each of these reporting persons is deemed a beneficial owner of the 3.6% of the shares of the Issuer held by Minerva Group, LP.  David P. Cohen is also deemed a beneficial owner of the 5.0% of the shares of the Issuer beneficially owned by Minerva Advisors LLC.

Based on a total of 20,336,183 shares of the Issuer's Common Stock outstanding as of October 31, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q for the period ended September 30, 2025.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>Minerva Advisors LLC* - 729,317
Minerva Group, LP - 729,317
Minerva GP, LP* - 729,317
Minerva GP, Inc.* - 729,317
David P. Cohen* - 729,317

*Each of these reporting persons is deemed a beneficial owner of the 729,317 shares of the Issuer held by Minerva Group, LP.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>Minerva Advisors LLC - 296,472
David P. Cohen** - 296,472

**David P. Cohen is deemed a beneficial owner of the 296,472 shares of the Issuer beneficially owned by Minerva Advisors LLC.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>Minerva Advisors LLC* - 729,317
Minerva Group, LP - 729,317
Minerva GP, LP* - 729,317
Minerva GP, Inc.* - 729,317
David P. Cohen* - 729,317

*Each of these reporting persons is deemed a beneficial owner of the 729,317 shares of the Issuer held by Minerva Group, LP.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>Minerva Advisors LLC - 296,472
David P. Cohen** - 296,472

**David P. Cohen is deemed a beneficial owner of the 296,472 shares of the Issuer beneficially owned by Minerva Advisors LLC.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
        <classOwnership5PercentOrLess>N</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
	<!-- Exhibit Information -->
	<!-- Signature -->
    <signatureInformation>
      <reportingPersonName>Minerva Advisors LLC</reportingPersonName>
      <signatureDetails>
        <signature>David P. Cohen</signature>
        <title>President</title>
        <date>12/03/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>MINERVA GROUP LP</reportingPersonName>
      <signatureDetails>
        <signature>David P. Cohen</signature>
        <title>Managing Partner</title>
        <date>12/03/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>MINERVA GP, LP</reportingPersonName>
      <signatureDetails>
        <signature>David P. Cohen</signature>
        <title>General Partner</title>
        <date>12/03/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>MINERVA GP, INC.</reportingPersonName>
      <signatureDetails>
        <signature>David P. Cohen</signature>
        <title>President</title>
        <date>12/03/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>COHEN DAVID P</reportingPersonName>
      <signatureDetails>
        <signature>David P. Cohen</signature>
        <title>Individual</title>
        <date>12/03/2025</date>
      </signatureDetails>
    </signatureInformation>
	</formData>
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