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Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2019   12,560,990    
Beginning balance at Dec. 31, 2019 $ 55,659 $ 13 $ 220,248 $ (164,602)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Exercise of stock options (in shares)   47,549    
Exercise of stock options 13   13  
Issuance of stock under Employee Stock Purchase Plan (in shares)   11,649    
Issuance of stock under Employee Stock Purchase Plan 142   142  
Stock-based compensation 2,694   2,694  
Exercise of common stock warrants (in shares)   32,120    
Exercise of common stock warrants 18   18  
Net loss $ (16,687)     (16,687)
Ending balance (in shares) at Dec. 31, 2020 12,652,308 12,652,308    
Ending balance at Dec. 31, 2020 $ 41,839 $ 13 223,115 (181,289)
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Issuance of stock in public offering, net of issuance costs of $4,435 (in shares)   4,255,000    
Issuance of stock in public offering, net of issuance costs of $4,435 64,709 $ 4 64,705  
Retirement of common stock in exchange for common stock warrant (in shares)   (804,951)    
Retirement of common stock in exchange for common stock warrant (12,775) $ (1) (12,774)  
Issuance of common stock warrant in exchange for retirement of common stock $ 12,775   12,775  
Exercise of stock options (in shares) 11,950 11,950    
Exercise of stock options $ 89   89  
Issuance of stock under Employee Stock Purchase Plan (in shares)   32,968    
Issuance of stock under Employee Stock Purchase Plan 390   390  
Stock-based compensation $ 4,728   4,728  
Exercise of common stock warrants (in shares) 17,719 17,719    
Exercise of common stock warrants $ 32   32  
Net loss $ (26,851)     (26,851)
Ending balance (in shares) at Dec. 31, 2021 16,164,994 16,164,994    
Ending balance at Dec. 31, 2021 $ 84,936 $ 16 $ 293,060 $ (208,140)