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Other Disclosures - Collaborations and Technology Licenses (Details)
€ in Millions, kr in Millions, $ in Millions
1 Months Ended 6 Months Ended 12 Months Ended
Jun. 10, 2020
USD ($)
item
Oct. 31, 2020
Jul. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Option
Jul. 31, 2018
USD ($)
item
Dec. 31, 2017
item
Jun. 30, 2021
USD ($)
item
Dec. 31, 2021
USD ($)
Option
item
Dec. 31, 2020
USD ($)
Dec. 31, 2012
Dec. 31, 2021
DKK (kr)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
DKK (kr)
Dec. 31, 2019
EUR (€)
Aug. 31, 2015
USD ($)
Collaborations and Technology Licenses                              
Investments accounted for using equity method | kr                     kr 371   kr 1,081    
Janssen                              
Collaborations and Technology Licenses                              
Royalty obligation expiration term after first sale of product               13 years              
Milestone payments receivable                       $ 191.0      
Upfront payment               $ 3.5              
Number of additional programs | item               10              
Initial payments received               $ 2.0              
Number of license exercised | item               14              
Number of license options remaining to be exercised | Option               0              
Novartis (Arzaerra/Ofatumumab)                              
Collaborations and Technology Licenses                              
Royalty percentage for non-cancer treatment               10.00%              
Lump sum payment received                 $ 30.0            
Seagen                              
Collaborations and Technology Licenses                              
Cost and profit sharing ratio   50                          
AbbVie                              
Collaborations and Technology Licenses                              
Number of additional candidates selected | item 4                            
Upfront payment $ 750.0   $ 750.0                        
Ratio of share of profits before income taxes 50                            
Number of performance obligations | item 4                            
Number of delivery license programs | item 3                            
Percentage of discover research and development cost responsible by the entity 100.00%                            
BioNTech                              
Collaborations and Technology Licenses                              
Number of additional candidates selected | item               2              
Upfront fee paid               $ 10.0              
Novo Nordisk A/S                              
Collaborations and Technology Licenses                              
Number of potential target pair combinations | item           5                  
Options to obtain commercial licenses | item           3                  
CureVac                              
Collaborations and Technology Licenses                              
Upfront fee payable       $ 10.0                      
Collaborative arrangement, Development, Regulatory and commercial milestone payment       $ 280.0                      
Options to obtain commercial licenses | Option       3                      
Option exercisable period       5 years                      
Investments accounted for using equity method                     318   kr 1,067 € 20  
Percentage of investment in common shares               35.00%              
Bolt                              
Collaborations and Technology Licenses                              
Investments accounted for using equity method             $ 15.0       kr 26        
Upfront fee paid             $ 10.0                
Threshold number of clinical candidates evaluated for development | item             3                
Co-developed development cost split ratio             50                
Milestone payments receivable             $ 285.0                
Immatics                              
Collaborations and Technology Licenses                              
Development regulatory and commercial milestone payments to be made         $ 550.0                    
Number of proprietary targets of license | item         3                    
Number of additional proprietary targets of license | item         2                    
Upfront fee paid         $ 54.0                    
Bottom of range [member] | Janssen                              
Collaborations and Technology Licenses                              
Tiered royalty percentage                   12.00%          
Bottom of range [member] | CureVac                              
Collaborations and Technology Licenses                              
Collaborative arrangement, Development, Regulatory and commercial milestone payment       $ 275.0                      
Top of range [member] | Janssen                              
Collaborations and Technology Licenses                              
Tiered royalty percentage                   20.00%          
Milestone payments receivable                       $ 175.0      
Top of range [member] | Novo Nordisk A/S                              
Collaborations and Technology Licenses                              
Collaborative arrangement, Development, Regulatory and commercial milestone payment                             $ 250.0
Top of range [member] | CureVac                              
Collaborations and Technology Licenses                              
Collaborative arrangement, Development, Regulatory and commercial milestone payment       $ 368.0                      
Development Regulatory and Sales Milestone | Top of range [member] | AbbVie                              
Collaborations and Technology Licenses                              
Receivables $ 3,150.0                            
Countries Outside United States and Japan | Bottom of range [member] | AbbVie                              
Collaborations and Technology Licenses                              
Royalty percent on sales 22.00%                            
Countries Outside United States and Japan | Top of range [member] | AbbVie                              
Collaborations and Technology Licenses                              
Royalty percent on sales 26.00%                            
Clinical Development and Commercial Success Across all Three Programs | Development Regulatory and Sales Milestone | AbbVie                              
Collaborations and Technology Licenses                              
Receivables $ 1,150.0                            
Success of all Four Next Generation Antibody Product Candidates Developed | Development Regulatory and Sales Milestone | AbbVie                              
Collaborations and Technology Licenses                              
Receivables $ 2,000.0