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Consolidated Statements of Expenses (USD $)
In Thousands, except Share data, unless otherwise specified
 12 Months Ended 108 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2011
Expenses:      
Research and development expense $ 10,742 $ 6,046 $ 37,425
Research and development employee stock-based compensation expense 866 1,084 3,273
Research and development non-employee stock-based compensation expense (70) 743 5,993
Fair value of common stock issued in exchange for licensing rights     3,954
Total research and development expense 11,538 7,873 50,645
General and administrative expense 6,863 5,493 27,973
Fair value of common stock warrants issued for general and administrative expense 108 718 2,402
Fair value of common stock issued in exchange for general and administrative expenses 73   354
General and administrative employee stock-based compensation expense 2,205 2,541 9,590
Total general and administrative expense 9,249 8,752 40,319
Operating loss (20,787) (16,625) (90,964)
Other income/(expense):      
Interest income, net 30 5 658
Loss on warrant exchange (900)   (900)
Other income, net 10,172 4,627 13,937
Total other income, net 9,302 4,632 13,695
Loss on warrant exchange (900)   (900)
Other income, net 10,172 4,627 13,937
Loss before provision for income taxes (11,485) (11,993) (77,269)
Provision for income taxes       
Net loss $ (11,485) $ (11,993) $ (77,269)
Net loss per common share:      
Basic and diluted loss per share $ (0.32) $ (0.67) $ 0
Weighted average common shares outstanding: basic and diluted 36,334,413 17,883,381