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License Agreements (Additional Information) (Detail) (USD $) | 0 Months Ended | 1 Months Ended | 12 Months Ended |  |  | 0 Months Ended
--- | --- | --- | --- | --- | --- | ---
Apr. 13, 2011 | Mar. 30, 2013 | Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2013 Orexo [Member] | Mar. 31, 2013 Orexo [Member] | Dec. 31, 2013 M D Anderson Cancer Center [Member] | Jan. 13, 2014 Subsequent Event [Member] Mills Pharmaceuticals LLC [Member]
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |
Annual maintenance fee |  |  |  |  |  |  |  | $ 200,000 |
Milestone payment for Phase 3 |  |  |  |  |  |  |  | 200,000 |
Cash paid for acquisition of Abstral rights |  | 10,000,000 | 15,143,000 |  |  |  |  |  |
Remaining cash held of Abstral rights |  |  |  |  |  |  | 5,000,000 |  |
Estimated year of licensed patents expiration |  |  |  |  |  | 2019 |  |  |
Upfront cash payment |  |  |  |  |  |  |  |  | 2,000,000
One-time payment of share upon achievement of regulatory milestones | 5,000,000 |  |  |  |  |  |  |  | 4,000,000
Contingent payment upon FDA approval |  |  |  |  |  |  |  |  | $ 3,000,000

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